SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u3x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A  49
LEU A  27
SER A 143
ILE A 141
ARG A 140
 None
 1.19A 1ddsB-3u3xA:
undetectable		 1ddsB-3u3xA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.16A 1gtfJ-3u3xA:
undetectable
1gtfK-3u3xA:
undetectable		 1gtfJ-3u3xA:
12.50
1gtfK-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 6 GLY A 296
VAL A 284
ALA A 154
SER A 152
 None
 0.99A 1p6kA-3u3xA:
undetectable		 1p6kA-3u3xA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.85A 1p7lD-3u3xA:
undetectable		 1p7lD-3u3xA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.85A 1p7lC-3u3xA:
undetectable		 1p7lC-3u3xA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 9 SER A 279
GLY A 277
VAL A 170
GLU A 169
ILE A 275
 None
 1.24A 1pw7B-3u3xA:
undetectable		 1pw7B-3u3xA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.83A 1rg9B-3u3xA:
undetectable		 1rg9B-3u3xA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.84A 1rg9A-3u3xA:
undetectable		 1rg9A-3u3xA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.85A 1rg9D-3u3xA:
undetectable		 1rg9D-3u3xA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.85A 1rg9C-3u3xA:
undetectable		 1rg9C-3u3xA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A 272
HIS A 298
GLY A 292
PRO A 266
GLY A 269
 None
 1.43A 2y6rC-3u3xA:
3.9		 2y6rC-3u3xA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 5 VAL A 257
GLN A 351
PHE A 211
ARG A 193
 None
 1.37A 3bjwB-3u3xA:
undetectable		 3bjwB-3u3xA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A  32
GLY A  33
GLU A  58
ASP A  60
ALA A  80
 None
 0.95A 3fuuA-3u3xA:
5.2		 3fuuA-3u3xA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 GLY A  33
GLU A  58
ASP A  60
LEU A  63
ALA A  80
 None
 0.69A 3grvA-3u3xA:
4.5		 3grvA-3u3xA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 ARG A 272
HIS A 298
GLY A 292
PRO A 266
GLY A 269
 None
 1.39A 3v3nA-3u3xA:
4.2		 3v3nA-3u3xA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_C_T1CC401_1
(TETX2 PROTEIN)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 ARG A 272
HIS A 298
GLY A 292
PRO A 266
GLY A 269
 None
 1.50A 3v3oC-3u3xA:
undetectable		 3v3oC-3u3xA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 ARG A 272
HIS A 298
GLY A 292
PRO A 266
GLY A 269
 None
 1.49A 4a99B-3u3xA:
4.1		 4a99B-3u3xA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 PHE A  29
ILE A  39
PHE A  67
ALA A  72
LEU A  47
 None
 0.88A 4e1gA-3u3xA:
undetectable		 4e1gA-3u3xA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 PHE A  29
ILE A  39
PHE A  67
ALA A  72
LEU A  47
 None
 0.90A 4e1gB-3u3xA:
undetectable		 4e1gB-3u3xA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 ASP A 188
ASN A  35
GLU A  58
GLU A 100
 None
 1.23A 4fexB-3u3xA:
undetectable		 4fexB-3u3xA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 HIS A  38
ILE A 203
PHE A 190
GLY A 197
GLY A 198
 None
 1.31A 4fglA-3u3xA:
3.4
4fglB-3u3xA:
4.4		 4fglA-3u3xA:
24.47
4fglB-3u3xA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 8 ALA A 354
GLN A 239
ASP A 240
ILE A 199
ILE A 203
 None
 1.15A 4kttD-3u3xA:
undetectable		 4kttD-3u3xA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.95A 4ndnD-3u3xA:
undetectable		 4ndnD-3u3xA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A  39
GLY A  33
ALA A  95
GLU A  58
GLU A  66
 None
 1.33A 4xt8A-3u3xA:
undetectable		 4xt8A-3u3xA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5eevA-3u3xA:
undetectable
5eevB-3u3xA:
undetectable		 5eevA-3u3xA:
12.50
5eevB-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5eewA-3u3xA:
undetectable
5eewB-3u3xA:
undetectable		 5eewA-3u3xA:
12.50
5eewB-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5eexA-3u3xA:
undetectable
5eexB-3u3xA:
undetectable		 5eexA-3u3xA:
12.50
5eexB-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5eeyA-3u3xA:
undetectable
5eeyB-3u3xA:
undetectable		 5eeyA-3u3xA:
12.50
5eeyB-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5eezA-3u3xA:
undetectable
5eezB-3u3xA:
undetectable		 5eezA-3u3xA:
12.50
5eezB-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5ef0A-3u3xA:
undetectable
5ef0B-3u3xA:
undetectable		 5ef0A-3u3xA:
12.50
5ef0B-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5ef1A-3u3xA:
undetectable
5ef1B-3u3xA:
undetectable		 5ef1A-3u3xA:
12.50
5ef1B-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5ef2A-3u3xA:
undetectable
5ef2B-3u3xA:
undetectable		 5ef2A-3u3xA:
12.50
5ef2B-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 253
THR A 251
GLY A 277
HIS A 172
ILE A 167
 None
 1.13A 5ef3A-3u3xA:
undetectable
5ef3B-3u3xA:
undetectable		 5ef3A-3u3xA:
12.50
5ef3B-3u3xA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 PRO A 153
ILE A  39
SER A 313
 None
 0.68A 5fsaA-3u3xA:
undetectable		 5fsaA-3u3xA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A  49
LEU A  27
SER A 143
ILE A 141
ARG A 140
 None
 1.11A 5hi6A-3u3xA:
undetectable		 5hi6A-3u3xA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 SER A 279
GLY A 277
VAL A 170
GLU A 169
ILE A 275
 None
 1.11A 5i3cB-3u3xA:
undetectable		 5i3cB-3u3xA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 ILE A  92
ALA A 105
LEU A 104
ALA A  95
ILE A  39
 None
 0.99A 5mvmD-3u3xA:
undetectable
5mvmE-3u3xA:
undetectable		 5mvmD-3u3xA:
12.78
5mvmE-3u3xA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3u3x OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A 354
GLN A 239
ILE A 199
ILE A 203
 None
 0.84A 5t8sA-3u3xA:
undetectable		 5t8sA-3u3xA:
23.98