SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		5 / 12 ILE B 106
LEU B  69
LEU B 147
PHE B 111
LEU B 112
 None
 1.13A 1g5yB-3u3yB:
undetectable		 1g5yB-3u3yB:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		5 / 12 LEU B 121
LEU B  37
ALA B  38
LEU B  44
THR B 150
 None
 1.36A 2aa5B-3u3yB:
undetectable		 2aa5B-3u3yB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		3 / 3 TYR B 129
ASP B  18
ASP B 193
 None
 0.85A 3ou6B-3u3yB:
undetectable		 3ou6B-3u3yB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		3 / 3 HIS B 200
SER B  68
GLU B  33
 None
 0.88A 3s8pA-3u3yB:
undetectable		 3s8pA-3u3yB:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		3 / 3 PRO B 132
MET B 232
TYR B 129
 None
 0.97A 4qa0A-3u3yB:
undetectable		 4qa0A-3u3yB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		3 / 3 PRO B 132
MET B 232
TYR B 129
 None
 1.02A 4qa2B-3u3yB:
undetectable		 4qa2B-3u3yB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		5 / 11 ALA B 105
LEU B 108
GLU B 137
LEU B  34
LEU B  67
 None
 1.19A 4wg0G-3u3yB:
undetectable
4wg0H-3u3yB:
undetectable
4wg0I-3u3yB:
undetectable		 4wg0G-3u3yB:
5.88
4wg0H-3u3yB:
5.88
4wg0I-3u3yB:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		5 / 11 ALA B 105
LEU B 108
GLU B 137
LEU B  34
LEU B  67
 None
 1.13A 4wg0K-3u3yB:
undetectable
4wg0L-3u3yB:
undetectable
4wg0M-3u3yB:
undetectable		 4wg0K-3u3yB:
5.88
4wg0L-3u3yB:
5.88
4wg0M-3u3yB:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3u3y THREE PRIME REPAIR
EXONUCLEASE 1
(Mus
musculus) 		5 / 12 PRO B   7
VAL B 153
ALA B 158
VAL B 219
LEU B 162
 None
 1.27A 5igpA-3u3yB:
undetectable		 5igpA-3u3yB:
24.79