SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 11 HIS B 805
HIS B 809
SER A 659
LEU B 811
LEU B 783
 None
 1.27A 1dmyA-3u44B:
undetectable		 1dmyA-3u44B:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 7 VAL A 710
SER A 711
ASP B 357
LYS B 356
 None
 1.28A 1hwiC-3u44A:
undetectable		 1hwiC-3u44A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 7 VAL A 710
SER A 711
ASP B 357
LYS B 356
 None
 1.28A 1hwiD-3u44A:
undetectable		 1hwiD-3u44A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		6 / 11 GLY A 810
GLY A 808
GLU A 551
ILE A 881
ASP A 531
THR A 915
 None
 1.41A 1jg3A-3u44A:
2.4		 1jg3A-3u44A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 12 GLY A 829
LEU A 332
LEU A 216
THR A 832
LEU A 335
 None
 1.36A 1jipA-3u44A:
undetectable		 1jipA-3u44A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ARG A 865
ARG A 910
ARG A 445
 None
 1.11A 1l7fA-3u44A:
undetectable		 1l7fA-3u44A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ARG A 865
ARG A 910
ARG A 445
 None
 1.10A 1l7hA-3u44A:
undetectable		 1l7hA-3u44A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 6 LEU B 680
ASP B 611
GLU A  72
ARG B 617
 None
 1.08A 1mt1A-3u44B:
undetectable
1mt1F-3u44B:
undetectable		 1mt1A-3u44B:
3.77
1mt1F-3u44B:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 8 THR A 430
ASP A  25
GLU A 417
LYS A 457
 None
 1.16A 1mxgA-3u44A:
undetectable		 1mxgA-3u44A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 5 GLU A  72
ARG B 617
LEU B 680
ASP B 611
 None
 1.10A 1n13B-3u44A:
undetectable
1n13C-3u44A:
undetectable		 1n13B-3u44A:
6.90
1n13C-3u44A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 LEU B 334
TYR B 340
LEU B 665
PRO B 661
TYR B 666
 None
 1.45A 1p33A-3u44B:
3.4		 1p33A-3u44B:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 LEU B 334
TYR B 340
LEU B 665
PRO B 661
TYR B 666
 None
 1.50A 1p33B-3u44B:
undetectable		 1p33B-3u44B:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 GLU B1147
TRP B1155
LYS B1036
 None
 1.20A 1qu2A-3u44B:
undetectable		 1qu2A-3u44B:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis;
Bacillus
subtilis) 		3 / 3 TYR B 366
ARG A 741
GLN A 737
 None
 1.03A 1tw4A-3u44B:
undetectable		 1tw4A-3u44B:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 5 ASP B 185
GLU B 184
LEU B  87
LEU B 181
 None
 0.93A 1u18B-3u44B:
undetectable		 1u18B-3u44B:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 7 LEU B 632
LEU B 158
PHE B 130
MET B 126
 None
 0.91A 1wrlE-3u44B:
undetectable
1wrlF-3u44B:
undetectable		 1wrlE-3u44B:
5.57
1wrlF-3u44B:
5.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ASP A 825
GLU A 502
TYR A 911
 None
 0.84A 1wsvA-3u44A:
undetectable		 1wsvA-3u44A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ARG A 771
SER A 188
TYR A 187
 None
 0.47A 1x70A-3u44A:
undetectable		 1x70A-3u44A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis;
Bacillus
subtilis) 		3 / 3 LYS B 161
ASP B 626
ASP A  58
 None
 1.14A 2br4A-3u44B:
2.4		 2br4A-3u44B:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 9 TYR A 718
LEU A 758
LEU A 630
LEU A 627
ALA A 747
 None
 1.36A 2bxeA-3u44A:
undetectable		 2bxeA-3u44A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		6 / 10 TYR A 718
LEU A 758
LEU A 630
LEU A 627
ILE A 765
ALA A 747
 None
 1.38A 2bxeB-3u44A:
undetectable		 2bxeB-3u44A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 8 PHE A 919
ALA A 913
ARG A 914
LEU A 860
 None
 1.06A 2bxkA-3u44A:
undetectable		 2bxkA-3u44A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 6 LYS A1174
GLN A1119
ILE A1229
PHE A1223
 None
 0.93A 2jn3A-3u44A:
undetectable		 2jn3A-3u44A:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ARG B  84
VAL B  75
THR B  79
 None
 0.82A 2nmzA-3u44B:
undetectable		 2nmzA-3u44B:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 10 ILE B 654
LEU B 614
ASN B 610
ASN A 102
VAL B 667
 None
 1.26A 2nnhB-3u44B:
undetectable		 2nnhB-3u44B:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ARG B  84
VAL B  75
THR B  79
 None
 0.83A 2nnkA-3u44B:
undetectable		 2nnkA-3u44B:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 5 LEU A 809
ALA A 807
TRP A 594
LEU A 589
 None
 1.14A 2oaxA-3u44A:
undetectable		 2oaxA-3u44A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ARG A 590
SER A 591
TYR A 916
 None
 0.96A 2q2hA-3u44A:
undetectable
2q2hB-3u44A:
undetectable		 2q2hA-3u44A:
7.84
2q2hB-3u44A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 7 LEU B 680
ASP B 611
GLU A  72
ARG B 617
 None
 1.03A 2qqdA-3u44B:
undetectable
2qqdE-3u44B:
undetectable		 2qqdA-3u44B:
3.77
2qqdE-3u44B:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 11 ILE A 881
ALA A 552
LEU A 602
ILE A 585
PHE A 805
 None
 1.02A 2w9sA-3u44A:
undetectable		 2w9sA-3u44A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 11 ILE A 881
ALA A 552
LEU A 602
ILE A 585
PHE A 805
 None
 1.00A 2w9sB-3u44A:
undetectable		 2w9sB-3u44A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 10 ILE A 881
ALA A 552
LEU A 602
ILE A 585
PHE A 805
 None
 1.00A 2w9sC-3u44A:
undetectable		 2w9sC-3u44A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 TYR B 169
GLU B 173
THR B 188
 None
 0.96A 2y7hB-3u44B:
undetectable		 2y7hB-3u44B:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 11 LEU B 614
MET B 683
VAL B 613
GLY B 612
ALA B 609
 None
 1.15A 2yy8A-3u44B:
2.5
2yy8B-3u44B:
2.3		 2yy8A-3u44B:
10.89
2yy8B-3u44B:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 5 VAL B 482
THR B 512
THR B 477
ARG B 478
 None
 1.07A 3bjwA-3u44B:
undetectable		 3bjwA-3u44B:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 5 VAL B 482
THR B 512
THR B 477
ARG B 478
 None
 1.12A 3bjwC-3u44B:
undetectable		 3bjwC-3u44B:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 6 LEU A 691
TYR A 695
LEU A 698
LEU A 678
 None
 0.66A 3f33A-3u44A:
5.1		 3f33A-3u44A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 10 LEU A 642
VAL A 651
ALA A 673
ILE A 661
LEU A 687
 None
 1.23A 3fl9A-3u44A:
undetectable		 3fl9A-3u44A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ASP A 298
LEU A 301
GLN A 895
 None
 0.64A 3g4lA-3u44A:
undetectable		 3g4lA-3u44A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ALA A 923
ARG A 926
LYS A 939
 None
 1.11A 3kp5B-3u44A:
3.2		 3kp5B-3u44A:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 7 GLU B1082
VAL B1080
VAL B1047
ALA B1004
 None
 0.99A 3kp6B-3u44B:
undetectable		 3kp6B-3u44B:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ARG B  84
VAL B  75
THR B  79
 None
 0.87A 3nduD-3u44B:
undetectable		 3nduD-3u44B:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 11 THR A 488
ASN A 477
SER A 480
LEU A 871
LEU A 878
 None
 1.36A 3ndvA-3u44A:
undetectable
3ndvB-3u44A:
undetectable		 3ndvA-3u44A:
15.52
3ndvB-3u44A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 11 LEU A 871
LEU A 878
THR A 488
ASN A 477
SER A 480
 None
 1.36A 3ndvC-3u44A:
undetectable
3ndvD-3u44A:
undetectable		 3ndvC-3u44A:
15.52
3ndvD-3u44A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 TYR B 211
GLY B 209
ASP B 208
 None
 0.73A 3ou6C-3u44B:
undetectable		 3ou6C-3u44B:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 7 PHE B 363
VAL B 588
ILE B 347
TYR B 342
 None
 0.99A 3pglA-3u44B:
undetectable		 3pglA-3u44B:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB511_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 5 SER B 575
GLU B 550
LEU B 547
GLN B 546
 None
 0.88A 3pgyB-3u44B:
undetectable		 3pgyB-3u44B:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ARG B  84
VAL B  75
THR B  79
 None
 0.84A 3pwrA-3u44B:
undetectable		 3pwrA-3u44B:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 THR A 424
ASP A  25
GLU A 429
 None
 0.75A 3qowA-3u44A:
undetectable		 3qowA-3u44A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 10 PHE B 213
PHE B 218
PHE B  68
ILE B 231
PHE B 233
 None
 1.39A 3t3qB-3u44B:
undetectable		 3t3qB-3u44B:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ARG B  84
VAL B  75
THR B  79
 None
 0.86A 3tl9A-3u44B:
undetectable		 3tl9A-3u44B:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 PRO B 215
THR B 214
LEU B 187
 None
 0.64A 3ttrA-3u44B:
undetectable		 3ttrA-3u44B:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 PHE A 179
LYS A 820
SER A 821
 None
 1.11A 3tyeB-3u44A:
undetectable		 3tyeB-3u44A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 10 ARG B 261
GLY B 636
VAL B 637
GLU B 638
ILE B 635
 None
 1.32A 3uayA-3u44B:
undetectable		 3uayA-3u44B:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 8 LEU B1144
LYS B1116
TYR B 975
LEU B 978
TYR B1113
 None
 1.49A 3v81A-3u44B:
undetectable		 3v81A-3u44B:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 6 TYR A 187
GLN A 183
GLU A 863
LEU A 823
 None
 1.41A 4ax8A-3u44A:
undetectable		 4ax8A-3u44A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 ILE B1063
ASP B1052
LEU B1055
PHE B1032
HIS B 903
 None
 1.29A 4b9zA-3u44B:
undetectable		 4b9zA-3u44B:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 VAL B 544
THR B 512
PHE B 386
ILE B 387
SER B 390
 None
 1.46A 4c49D-3u44B:
undetectable		 4c49D-3u44B:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 6 PHE A 949
GLY A 921
PRO A 922
LEU A 491
 None
 1.02A 4dubA-3u44A:
undetectable		 4dubA-3u44A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 7 TYR B 432
LEU B 429
TRP B 443
ASN B 475
 None
 1.14A 4f8yC-3u44B:
undetectable
4f8yD-3u44B:
undetectable		 4f8yC-3u44B:
10.21
4f8yD-3u44B:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 7 ARG A 189
GLY A 353
ILE A 350
GLU A 195
 None
 1.12A 4g0vA-3u44A:
2.9		 4g0vA-3u44A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 LYS B 439
TYR B 400
ARG B 399
 None
 1.11A 4gc9A-3u44B:
undetectable		 4gc9A-3u44B:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 ARG B 253
GLY B 642
GLY B 643
LEU B 624
SER B 625
 None
 0.99A 4htfA-3u44B:
2.3		 4htfA-3u44B:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 ARG B 253
GLY B 642
GLY B 643
LEU B 624
SER B 625
 None
 1.00A 4htfB-3u44B:
3.1		 4htfB-3u44B:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 7 THR B  44
LEU B 187
GLN B 223
LEU B 224
 None
 0.87A 4ib4A-3u44B:
2.3		 4ib4A-3u44B:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 12 GLY A 138
GLY A 142
ALA A 359
ALA A 133
ASP A 370
 None
 1.11A 4kicA-3u44A:
2.1		 4kicA-3u44A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		5 / 12 GLY A 138
GLY A 142
ALA A 359
ALA A 133
ASP A 370
 None
 1.09A 4kicB-3u44A:
undetectable		 4kicB-3u44A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis;
Bacillus
subtilis) 		5 / 12 GLU B 705
THR B 701
GLU B 325
GLU B 703
LYS A 734
 None
 1.42A 4njhA-3u44B:
undetectable		 4njhA-3u44B:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 5 ILE B  19
ARG B 283
GLU B  50
VAL B  65
 None
 0.98A 4nkxD-3u44B:
undetectable		 4nkxD-3u44B:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 9 LEU B1144
LYS B1116
TYR B 975
LEU B 978
TYR B1113
 None
 1.41A 4q0bC-3u44B:
1.5		 4q0bC-3u44B:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 THR B 313
GLU B 330
ARG B 329
PHE B 605
LEU B 700
 None
 1.49A 4uinH-3u44B:
undetectable
4uinL-3u44B:
undetectable		 4uinH-3u44B:
10.95
4uinL-3u44B:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 7 PHE A 150
LEU A 149
THR A 169
VAL A 181
 None
 0.90A 4wnvD-3u44A:
undetectable		 4wnvD-3u44A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 LYS A 279
ARG A 280
HIS A 270
 None
 1.11A 4zbrA-3u44A:
undetectable		 4zbrA-3u44A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		4 / 6 TYR B 655
ARG B   9
GLY B   8
SER B  12
 None
 1.12A 5bphA-3u44B:
2.5		 5bphA-3u44B:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 THR B 236
THR B 255
PHE B 210
 None
 0.70A 5cxvA-3u44B:
undetectable		 5cxvA-3u44B:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis;
Bacillus
subtilis) 		3 / 3 ASP A 786
LEU B 732
ARG B 735
 None
 0.72A 5e8qA-3u44A:
undetectable		 5e8qA-3u44A:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 5 ILE A 920
PHE A 949
SER A 487
ALA A 923
 None
 1.19A 5msdA-3u44A:
2.3		 5msdA-3u44A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 8 LEU A1171
PHE A1111
LEU A1073
ILE A1071
 None
 0.94A 5mzjA-3u44A:
2.8		 5mzjA-3u44A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 HIS A 955
ASP A 531
HIS A 887
 None
 0.95A 5n1tW-3u44A:
undetectable		 5n1tW-3u44A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 4 GLU A 524
THR A 523
THR A 488
LEU A 880
 None
 1.35A 5v96A-3u44A:
undetectable		 5v96A-3u44A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 4 GLU A 524
THR A 523
THR A 488
LEU A 880
 None
 1.36A 5v96B-3u44A:
undetectable		 5v96B-3u44A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 4 GLU A 524
THR A 523
THR A 488
LEU A 880
 None
 1.37A 5v96C-3u44A:
undetectable		 5v96C-3u44A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		4 / 4 GLU A 524
THR A 523
THR A 488
LEU A 880
 None
 1.38A 5v96D-3u44A:
undetectable		 5v96D-3u44A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		5 / 12 SER B 897
LEU B 900
ILE B 837
ALA B 863
GLY B 827
 None
 1.07A 5veuA-3u44B:
undetectable		 5veuA-3u44B:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A
(Bacillus
subtilis) 		3 / 3 ARG A 926
PHE A 492
LEU A 905
 None
 0.77A 5x1bC-3u44A:
2.1		 5x1bC-3u44A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 GLU B 124
LEU B  96
ARG B  97
 None
 0.78A 6d8fA-3u44B:
undetectable		 6d8fA-3u44B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ASN B 610
PRO B 670
GLN B 316
 None
 0.94A 6jnhA-3u44B:
3.3		 6jnhA-3u44B:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B
(Bacillus
subtilis) 		3 / 3 ASN B 610
PRO B 670
GLN B 316
 None
 0.94A 6jogA-3u44B:
undetectable		 6jogA-3u44B:
9.11