SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u4k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3u4k FIMBRIA ADHESIN
PROTEIN
(Klebsiella
pneumoniae) 		5 / 11 SER A 104
LEU A 133
THR A 132
ILE A  99
ILE A 136
 None
 1.04A 1pkvA-3u4kA:
undetectable
1pkvB-3u4kA:
undetectable		 1pkvA-3u4kA:
20.22
1pkvB-3u4kA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3u4k FIMBRIA ADHESIN
PROTEIN
(Klebsiella
pneumoniae) 		5 / 11 ILE A 136
SER A 104
LEU A 133
THR A 132
ILE A  99
 None
 1.03A 1pkvA-3u4kA:
undetectable
1pkvB-3u4kA:
undetectable		 1pkvA-3u4kA:
20.22
1pkvB-3u4kA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3u4k FIMBRIA ADHESIN
PROTEIN
(Klebsiella
pneumoniae) 		5 / 11 SER A 175
GLY A 100
THR A 142
LEU A  84
ILE A 135
 None
 1.15A 4pghA-3u4kA:
undetectable		 4pghA-3u4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3u4k FIMBRIA ADHESIN
PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 SER A 175
GLY A 100
THR A 142
LEU A  84
ILE A 135
 None
 1.11A 4pghB-3u4kA:
undetectable		 4pghB-3u4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3u4k FIMBRIA ADHESIN
PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 SER A 175
GLY A 100
THR A 142
LEU A  84
ILE A 135
 None
 1.13A 4pghD-3u4kA:
undetectable		 4pghD-3u4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 3u4k FIMBRIA ADHESIN
PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 ILE A  96
PRO A  97
ILE A  99
 None
 0.40A 5hw8F-3u4kA:
undetectable		 5hw8F-3u4kA:
22.63