SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 8 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.52A 1os6A-3u4vA:
undetectable		 1os6A-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 7 TYR A 306
PHE A 266
PHE A 250
ILE A 308
 None
 1.23A 2zseA-3u4vA:
undetectable		 2zseA-3u4vA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 5 GLN A 292
PHE A 293
LEU A 299
PHE A 230
 None
 1.30A 3ablC-3u4vA:
undetectable
3ablJ-3u4vA:
undetectable		 3ablC-3u4vA:
16.35
3ablJ-3u4vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 8 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.55A 3selX-3u4vA:
undetectable		 3selX-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 6 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.63A 3sj1X-3u4vA:
undetectable		 3sj1X-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		3 / 3 GLN A 218
ASP A 256
GLN A 260
 None
 0.86A 4aztA-3u4vA:
undetectable		 4aztA-3u4vA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 7 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.57A 4hbfA-3u4vA:
undetectable		 4hbfA-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 7 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.53A 4hc3A-3u4vA:
undetectable		 4hc3A-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 6 GLN A 292
PHE A 293
LEU A 299
PHE A 230
 None
 1.14A 5z85P-3u4vA:
undetectable
5z85W-3u4vA:
undetectable		 5z85P-3u4vA:
16.35
5z85W-3u4vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 6 GLN A 292
PHE A 293
LEU A 299
PHE A 230
 None
 1.13A 5zcoP-3u4vA:
undetectable
5zcoW-3u4vA:
undetectable		 5zcoP-3u4vA:
16.35
5zcoW-3u4vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82
(Tetrahymena
thermophila) 		4 / 6 GLN A 292
PHE A 293
LEU A 299
PHE A 230
 None
 1.17A 6nmpC-3u4vA:
undetectable
6nmpJ-3u4vA:
undetectable		 6nmpC-3u4vA:
16.35
6nmpJ-3u4vA:
21.43