SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 8 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.89A 1v54C-3u58A:
undetectable
1v54J-3u58A:
undetectable		 1v54C-3u58A:
21.88
1v54J-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 8 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.89A 1v54P-3u58A:
undetectable
1v54W-3u58A:
undetectable		 1v54P-3u58A:
21.88
1v54W-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.87A 1v55C-3u58A:
undetectable
1v55J-3u58A:
undetectable		 1v55C-3u58A:
21.88
1v55J-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.88A 1v55P-3u58A:
undetectable
1v55W-3u58A:
undetectable		 1v55P-3u58A:
21.88
1v55W-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 8 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.85A 2dyrC-3u58A:
undetectable
2dyrJ-3u58A:
undetectable		 2dyrC-3u58A:
21.88
2dyrJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 8 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.88A 2dyrP-3u58A:
undetectable
2dyrW-3u58A:
undetectable		 2dyrP-3u58A:
21.88
2dyrW-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.85A 2dysC-3u58A:
undetectable
2dysJ-3u58A:
undetectable		 2dysC-3u58A:
21.88
2dysJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.82A 2dysP-3u58A:
undetectable
2dysW-3u58A:
undetectable		 2dysP-3u58A:
21.88
2dysW-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.88A 2eijC-3u58A:
undetectable
2eijJ-3u58A:
undetectable		 2eijC-3u58A:
21.88
2eijJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.88A 2eijP-3u58A:
undetectable
2eijW-3u58A:
undetectable		 2eijP-3u58A:
21.88
2eijW-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 8 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.88A 2eikP-3u58A:
undetectable
2eikW-3u58A:
undetectable		 2eikP-3u58A:
21.88
2eikW-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 8 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.87A 2eilC-3u58A:
undetectable
2eilJ-3u58A:
undetectable		 2eilC-3u58A:
21.88
2eilJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.82A 2eimC-3u58A:
undetectable
2eimJ-3u58A:
undetectable		 2eimC-3u58A:
21.88
2eimJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.90A 2einC-3u58A:
undetectable
2einJ-3u58A:
undetectable		 2einC-3u58A:
21.88
2einJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.89A 2zxwC-3u58A:
undetectable
2zxwJ-3u58A:
undetectable		 2zxwC-3u58A:
21.88
2zxwJ-3u58A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LEU A 392
ASP A 411
TRP A 439
SER A 467
 None
 1.13A 3dzgA-3u58A:
undetectable		 3dzgA-3u58A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LEU A 392
ASP A 411
TRP A 439
SER A 467
 None
 1.16A 3dzgB-3u58A:
undetectable		 3dzgB-3u58A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 6 LYS A 302
GLU A 289
GLY A 288
GLY A 287
 None
 0.87A 5a06D-3u58A:
undetectable		 5a06D-3u58A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 7 LYS A 457
LEU A 456
GLN A 455
LEU A 389
 None
 0.92A 5b3sP-3u58A:
undetectable		 5b3sP-3u58A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3u58 TETRAHYMENA TEB1 AB
(Tetrahymena
thermophila) 		4 / 6 GLN A 292
PHE A 293
LEU A 299
PHE A 230
 None
 1.34A 6nmpC-3u58A:
undetectable
6nmpJ-3u58A:
undetectable		 6nmpC-3u58A:
21.88
6nmpJ-3u58A:
18.13