SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3u5r UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 ASP E 177
ALA E 165
LYS E 171
THR E 174
 None
 1.41A 4w5qA-3u5rE:
undetectable		 4w5qA-3u5rE:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 3u5r UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 TYR E 123
GLU E  79
GLY E 122
LEU E 178
ALA E  65
 None
 0.96A 4wcxC-3u5rE:
undetectable		 4wcxC-3u5rE:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 3u5r UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 7 TYR E 127
TYR E 121
GLU E 117
PHE E 125
 None
 1.05A 5aclA-3u5rE:
undetectable		 5aclA-3u5rE:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3u5r UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		4 / 8 SER E 198
PHE E 148
VAL E  74
ILE E  98
 None
 1.14A 5vkqB-3u5rE:
undetectable
5vkqC-3u5rE:
undetectable		 5vkqB-3u5rE:
8.31
5vkqC-3u5rE:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 3u5r UNCHARACTERIZED
PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ILE E  32
GLY E 160
THR E  27
ALA E  65
VAL E  64
 None
 1.17A 5x66F-3u5rE:
undetectable		 5x66F-3u5rE:
22.26