SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
3u60 DNA POLYMERASE
ACCESSORY PROTEIN 62

(Escherichia
virus
T4)
4 / 4 THR A 146
LEU A 151
VAL A 154
LEU A 158
None
0.89A 1fbmB-3u60A:
undetectable
1fbmB-3u60A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
3u60 DNA POLYMERASE
ACCESSORY PROTEIN 62

(Escherichia
virus
T4)
4 / 6 SER A  19
GLU A  12
ASP A  30
ASP A  21
None
1.40A 4blvA-3u60A:
undetectable
4blvA-3u60A:
22.90