SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3u66 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		4 / 7 TYR A  14
GLN A 133
PHE A 162
VAL A 159
 None
 1.04A 3jwqC-3u66A:
undetectable		 3jwqC-3u66A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3u66 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 12 GLN A  22
LEU A  23
GLY A  16
GLU A  49
ALA A  46
 None
 1.05A 4pclA-3u66A:
undetectable		 4pclA-3u66A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3u66 PUTATIVE TYPE VI
SECRETION PROTEIN
(Escherichia
coli) 		5 / 6 ILE A 152
ALA A 154
LEU A 155
ILE A 111
TYR A 140
 None
 1.45A 5mvmB-3u66A:
3.5
5mvmC-3u66A:
3.5		 5mvmB-3u66A:
18.56
5mvmC-3u66A:
18.56