SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3u6r ANTIBODY 1:7 (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 7 GLY H 113
GLN H  38
ILE H 108
PRO H 105
 None
 1.08A 1rxcF-3u6rH:
undetectable		 1rxcF-3u6rH:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 3u6r ANTIBODY 1:7 (HEAVY
CHAIN)
ANTIBODY 1:7 (LIGHT
CHAIN)
(Homo
sapiens;
Homo
sapiens) 		4 / 8 ARG H 109
ILE H 108
ARG L 239
PRO H 105
 SO4  H 150 (-3.4A)
None
SO4  H 150 (-4.5A)
None
 1.00A 3fxrA-3u6rH:
undetectable		 3fxrA-3u6rH:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3u6r ANTIBODY 1:7 (LIGHT
CHAIN)
(Homo
sapiens) 		5 / 12 PHE L 210
GLY L 164
LEU L 226
GLU L 227
SER L 224
 None
 1.35A 3tbgA-3u6rL:
undetectable		 3tbgA-3u6rL:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3u6r ANTIBODY 1:7 (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 8 SER H  72
ILE H  73
TRP H  39
GLU H  85
 None
 1.25A 4cx7C-3u6rH:
undetectable
4cx7D-3u6rH:
undetectable		 4cx7C-3u6rH:
14.49
4cx7D-3u6rH:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3u6r ANTIBODY 1:7 (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 7 GLY H 113
GLN H  38
ILE H 108
PRO H 105
 None
 1.07A 4e1vB-3u6rH:
undetectable		 4e1vB-3u6rH:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 3u6r ANTIBODY 1:7 (HEAVY
CHAIN)
(Homo
sapiens) 		4 / 6 ARG H  34
ALA H  82
ASP H  77
SER H  72
 None
 1.12A 4ot2A-3u6rH:
undetectable		 4ot2A-3u6rH:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 3u6r ANTIBODY 1:7 (LIGHT
CHAIN)
(Homo
sapiens) 		4 / 8 THR L 222
SER L 211
THR L 220
SER L 213
 None
 1.01A 5l4eA-3u6rL:
undetectable
5l4eB-3u6rL:
undetectable
5l4eC-3u6rL:
undetectable
5l4eD-3u6rL:
undetectable
5l4eE-3u6rL:
undetectable		 5l4eA-3u6rL:
17.34
5l4eB-3u6rL:
17.34
5l4eC-3u6rL:
17.34
5l4eD-3u6rL:
17.34
5l4eE-3u6rL:
17.34