SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u7b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 SER A 142
VAL A 143
LEU A 104
TYR A 152
 None
 1.09A 1fduB-3u7bA:
2.3		 1fduB-3u7bA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 11 THR A  22
GLU A  29
HIS A  68
GLY A 286
GLU A  45
 None
 1.44A 1i7qA-3u7bA:
undetectable		 1i7qA-3u7bA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 10 THR A  22
GLU A  29
HIS A  68
GLY A 286
GLU A  45
 None
 1.42A 1i7qC-3u7bA:
undetectable		 1i7qC-3u7bA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 LEU A 246
ALA A   2
ALA A   8
VAL A 270
MET A   9
 None
 1.12A 1rbpA-3u7bA:
undetectable		 1rbpA-3u7bA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 6 TYR A 170
ASP A 240
THR A 124
GLU A  78
 None
 1.42A 2dttB-3u7bA:
undetectable
2dttC-3u7bA:
undetectable		 2dttB-3u7bA:
17.39
2dttC-3u7bA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 THR A 320
ILE A 269
LYS A  14
LEU A 246
LEU A 231
 None
 1.25A 3a50E-3u7bA:
undetectable		 3a50E-3u7bA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 11 THR A 320
ILE A 269
LYS A  14
LEU A 246
LEU A 231
 None
 1.19A 3a51A-3u7bA:
undetectable		 3a51A-3u7bA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 THR A 320
ILE A 269
LYS A  14
LEU A 246
LEU A 231
 None
 1.17A 3a51D-3u7bA:
undetectable		 3a51D-3u7bA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		3 / 3 TYR A 178
TYR A 243
ILE A 269
 EDO  A 402 (-3.7A)
None
None
 0.84A 3eteA-3u7bA:
undetectable
3eteB-3u7bA:
undetectable		 3eteA-3u7bA:
19.92
3eteB-3u7bA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		3 / 3 HIS A 125
ARG A  80
GLU A  78
 None
 0.96A 3qf1A-3u7bA:
undetectable		 3qf1A-3u7bA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 6 LEU A 246
VAL A 284
PHE A  17
VAL A 270
 None
 1.02A 3soaA-3u7bA:
undetectable		 3soaA-3u7bA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		3 / 3 TRP A 293
VAL A 284
TRP A 285
 None
 1.20A 3zq8C-3u7bA:
undetectable
3zq8D-3u7bA:
undetectable		 3zq8C-3u7bA:
3.99
3zq8D-3u7bA:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 9 ALA A 186
ASP A 173
GLY A 179
VAL A 241
ILE A 203
 None
 1.23A 4ll3B-3u7bA:
undetectable		 4ll3B-3u7bA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 GLY A 286
ILE A  32
GLY A  28
SER A 292
PHE A 311
 None
 1.01A 4obwC-3u7bA:
2.3		 4obwC-3u7bA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 11 GLY A 271
ALA A 263
LEU A 306
ILE A 324
MET A   9
 None
 1.16A 4xumB-3u7bA:
undetectable		 4xumB-3u7bA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 VAL A 276
GLY A 204
LEU A 205
THR A 244
 None
 0.98A 5sxqA-3u7bA:
undetectable		 5sxqA-3u7bA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 VAL A 276
GLY A 204
LEU A 205
THR A 244
 None
 0.96A 5sxtA-3u7bA:
undetectable		 5sxtA-3u7bA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 VAL A 276
GLY A 204
LEU A 205
THR A 244
 None
 0.95A 5sxtB-3u7bA:
undetectable		 5sxtB-3u7bA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3u7b ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 VAL A 276
GLY A 204
LEU A 205
THR A 244
 None
 0.95A 5syjB-3u7bA:
undetectable		 5syjB-3u7bA:
19.39