SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3u8v METAL-BINDING
PROTEIN SMBP
(Nitrosomonas
europaea) 		5 / 11 HIS A   3
ALA A  10
SER A  36
GLY A  55
ILE A  56
 None
 1.22A 2uxpB-3u8vA:
undetectable		 2uxpB-3u8vA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3u8v METAL-BINDING
PROTEIN SMBP
(Nitrosomonas
europaea) 		5 / 11 HIS A   3
HIS A   6
ALA A  10
GLY A  55
ILE A  56
 None
NI  A  94 (-3.2A)
None
None
None
 0.81A 2uxpB-3u8vA:
undetectable		 2uxpB-3u8vA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3u8v METAL-BINDING
PROTEIN SMBP
(Nitrosomonas
europaea) 		4 / 4 ALA A  14
ALA A  17
ALA A  78
ALA A  81
 None
 0.72A 6gtqA-3u8vA:
undetectable
6gtqB-3u8vA:
0.2		 6gtqA-3u8vA:
20.99
6gtqB-3u8vA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3u8v METAL-BINDING
PROTEIN SMBP
(Nitrosomonas
europaea) 		4 / 4 ALA A  78
ALA A  81
ALA A  14
ALA A  17
 None
 0.72A 6gtqA-3u8vA:
undetectable
6gtqB-3u8vA:
0.2		 6gtqA-3u8vA:
20.99
6gtqB-3u8vA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3u8v METAL-BINDING
PROTEIN SMBP
(Nitrosomonas
europaea) 		5 / 11 ALA A  14
ALA A  33
ALA A  17
GLY A  55
ALA A  81
 None
 0.92A 6hwdK-3u8vA:
undetectable
6hwdL-3u8vA:
undetectable		 6hwdK-3u8vA:
18.95
6hwdL-3u8vA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3u8v METAL-BINDING
PROTEIN SMBP
(Nitrosomonas
europaea) 		5 / 11 ALA A  14
ALA A  33
ALA A  17
GLY A  55
ALA A  81
 None
 0.92A 6hwdY-3u8vA:
undetectable
6hwdZ-3u8vA:
undetectable		 6hwdY-3u8vA:
18.95
6hwdZ-3u8vA:
17.31