SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u92'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 8 LEU A  39
GLY A 216
LEU A 242
TYR A  35
 None
 0.86A 1jlbA-3u92A:
undetectable		 1jlbA-3u92A:
20.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 12 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.85A 1lbcA-3u92A:
37.3
1lbcC-3u92A:
37.3		 1lbcA-3u92A:
52.09
1lbcC-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 9 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.73A 1lbcB-3u92A:
37.2		 1lbcB-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 12 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.69A 1lbcA-3u92A:
37.4
1lbcC-3u92A:
37.3		 1lbcA-3u92A:
52.09
1lbcC-3u92A:
52.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 12 THR A 179
GLY A 175
GLU A 174
VAL A 169
TYR A 114
 None
 1.30A 1n2xA-3u92A:
undetectable		 1n2xA-3u92A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 11 LEU A  47
GLY A  48
SER A  50
VAL A   8
LEU A  84
 None
 0.89A 2kawA-3u92A:
undetectable		 2kawA-3u92A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 11 SER A 102
LEU A  40
ILE A 229
ALA A 232
LEU A 242
 None
 1.10A 2v0mA-3u92A:
undetectable		 2v0mA-3u92A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 6 GLY A  62
GLY A 140
MET A 143
ASN A  71
 None
KAI  A 258 (-3.3A)
None
None
 0.97A 3e9rA-3u92A:
undetectable		 3e9rA-3u92A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 6 GLY A  62
GLY A 140
MET A 143
ASN A  71
 None
KAI  A 258 (-3.3A)
None
None
 0.96A 3e9rC-3u92A:
undetectable		 3e9rC-3u92A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 12 LEU A  47
LEU A  39
LEU A  40
LEU A  84
LEU A 236
 None
 1.09A 3erdA-3u92A:
undetectable		 3erdA-3u92A:
24.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 11 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.76A 3h6tA-3u92A:
37.4
3h6tC-3u92A:
37.3		 3h6tA-3u92A:
52.09
3h6tC-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_B_CYZB265_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 9 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.83A 3h6tB-3u92A:
37.3		 3h6tB-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 11 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.74A 3h6tA-3u92A:
37.4
3h6tC-3u92A:
37.3		 3h6tA-3u92A:
52.09
3h6tC-3u92A:
52.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 12 LEU A  47
LEU A  39
LEU A  40
LEU A  84
LEU A 236
 None
 1.07A 3hm1A-3u92A:
undetectable		 3hm1A-3u92A:
25.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 10 ILE A  91
PRO A 104
SER A 212
LYS A 213
GLY A 214
 None
 0.65A 3ik6B-3u92A:
37.5
3ik6E-3u92A:
37.1		 3ik6B-3u92A:
51.34
3ik6E-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 12 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.94A 3iltB-3u92A:
34.3
3iltE-3u92A:
33.8		 3iltB-3u92A:
51.34
3iltE-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 10 LYS A 103
PRO A 104
MET A 106
LEU A 242
LYS A 246
 None
None
None
None
ZN  A 259 (-3.5A)
 0.78A 3iltB-3u92A:
34.3
3iltE-3u92A:
33.8		 3iltB-3u92A:
51.34
3iltE-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 10 PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
ZN  A 259 (-3.5A)
 0.74A 3iltB-3u92A:
34.3
3iltE-3u92A:
33.8		 3iltB-3u92A:
51.34
3iltE-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 11 ILE A  91
PRO A 104
SER A 212
LYS A 213
GLY A 214
 None
 0.65A 3iluB-3u92A:
37.2
3iluE-3u92A:
37.5		 3iluB-3u92A:
51.34
3iluE-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		5 / 8 TYR A  35
PRO A 104
MET A 106
LEU A 242
LYS A 246
 None
None
None
None
ZN  A 259 (-3.5A)
 0.42A 3lsfH-3u92A:
36.8		 3lsfH-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 7 TYR A  35
MET A 106
LEU A 242
LYS A 246
 None
None
None
ZN  A 259 (-3.5A)
 0.37A 3lslA-3u92A:
36.9
3lslD-3u92A:
36.8		 3lslA-3u92A:
51.34
3lslD-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 8 ILE A  91
PRO A 104
SER A 212
GLY A 214
 None
 0.28A 3lslA-3u92A:
36.9
3lslD-3u92A:
36.7		 3lslA-3u92A:
51.34
3lslD-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 7 TYR A  35
MET A 106
LEU A 242
LYS A 246
 None
None
None
ZN  A 259 (-3.5A)
 0.43A 3lslA-3u92A:
36.9
3lslD-3u92A:
36.8		 3lslA-3u92A:
51.34
3lslD-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 8 ILE A  91
PRO A 104
SER A 212
GLY A 214
 None
 0.26A 3lslA-3u92A:
37.0
3lslD-3u92A:
36.7		 3lslA-3u92A:
51.34
3lslD-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 6 TYR A  35
MET A 106
LEU A 242
LYS A 246
 None
None
None
ZN  A 259 (-3.5A)
 0.48A 3lslG-3u92A:
36.6		 3lslG-3u92A:
51.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 9 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.82A 3tkdA-3u92A:
37.7		 3tkdA-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 5 ILE A  91
PRO A 104
LYS A 213
GLY A 214
 None
 0.31A 3tkdB-3u92A:
37.6		 3tkdB-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 5 ILE A  91
PRO A 104
LYS A 213
GLY A 214
 None
 0.30A 3tkdA-3u92A:
37.7		 3tkdA-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 5 PRO A 104
SER A 212
LYS A 213
GLY A 214
 None
 0.67A 3tkdA-3u92A:
37.7		 3tkdA-3u92A:
52.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKD_B_CYZB267_2
(GLUTAMATE RECEPTOR 2)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		6 / 9 LYS A 103
PRO A 104
MET A 106
LEU A 234
LEU A 242
LYS A 246
 None
None
None
None
None
ZN  A 259 (-3.5A)
 0.84A 3tkdB-3u92A:
37.7		 3tkdB-3u92A:
52.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 6 ASN A 172
GLU A 189
TYR A 195
GLU A  13
 KAI  A 258 (-3.1A)
KAI  A 258 (-2.5A)
None
KAI  A 258 (-3.1A)
 1.06A 4mi4A-3u92A:
undetectable		 4mi4A-3u92A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		4 / 7 ASN A 172
GLU A 189
TYR A 195
GLU A  13
 KAI  A 258 (-3.1A)
KAI  A 258 (-2.5A)
None
KAI  A 258 (-3.1A)
 1.07A 4mi4A-3u92A:
undetectable
4mi4C-3u92A:
undetectable		 4mi4A-3u92A:
22.92
4mi4C-3u92A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3u92 GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 3
(Rattus
norvegicus) 		3 / 3 SER A 122
ALA A 123
THR A 153
 None
 0.73A 5n0xB-3u92A:
undetectable		 5n0xB-3u92A:
23.47