SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 VAL A  64
LEU A  51
LEU A  27
LEU A  23
LEU A  32
 None
 1.05A 1mx1C-3u9gA:
undetectable		 1mx1C-3u9gA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 VAL A  64
LEU A  51
LEU A  27
LEU A  23
LEU A  32
 None
 1.06A 1mx1F-3u9gA:
undetectable		 1mx1F-3u9gA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 7 SER A 141
ARG A  71
LEU A  85
HIS A 124
 None
 1.14A 2f78A-3u9gA:
undetectable		 2f78A-3u9gA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 SER A 141
ARG A  71
LEU A  85
HIS A 124
 None
 1.12A 2f8dA-3u9gA:
undetectable		 2f8dA-3u9gA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A  82
CYH A  73
HIS A  86
 ZN  A 226 (-2.3A)
ZN  A 226 (-2.3A)
ZN  A 226 (-3.1A)
 0.87A 2iwkA-3u9gA:
undetectable		 2iwkA-3u9gA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A  96
CYH A 106
HIS A 110
 ZN  A 227 (-2.3A)
ZN  A 227 (-2.4A)
ZN  A 227 (-3.1A)
 0.77A 2iwkA-3u9gA:
undetectable		 2iwkA-3u9gA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A  82
CYH A  73
HIS A  86
 ZN  A 226 (-2.3A)
ZN  A 226 (-2.3A)
ZN  A 226 (-3.1A)
 0.86A 2iwkB-3u9gA:
undetectable		 2iwkB-3u9gA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A  96
CYH A 106
HIS A 110
 ZN  A 227 (-2.3A)
ZN  A 227 (-2.4A)
ZN  A 227 (-3.1A)
 0.76A 2iwkB-3u9gA:
undetectable		 2iwkB-3u9gA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A 182
CYH A 187
HIS A 191
 ZN  A 229 (-2.3A)
ZN  A 229 (-2.3A)
ZN  A 229 (-3.3A)
 0.88A 2iwkB-3u9gA:
undetectable		 2iwkB-3u9gA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 GLN A 160
GLY A 155
HIS A 172
CYH A 150
 None
None
ZN  A 228 (-3.3A)
ZN  A 228 (-2.3A)
 1.44A 3ai8B-3u9gA:
undetectable		 3ai8B-3u9gA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 VAL A  64
VAL A  65
THR A  22
ARG A  20
 None
 1.10A 3bjwA-3u9gA:
undetectable		 3bjwA-3u9gA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 VAL A  64
VAL A  65
THR A  22
ARG A  20
 None
 1.12A 3bjwC-3u9gA:
undetectable		 3bjwC-3u9gA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A  96
CYH A 106
HIS A 110
 ZN  A 227 (-2.3A)
ZN  A 227 (-2.4A)
ZN  A 227 (-3.1A)
 0.88A 3dtuB-3u9gA:
undetectable		 3dtuB-3u9gA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 CYH A  96
CYH A 106
HIS A 110
 ZN  A 227 (-2.3A)
ZN  A 227 (-2.4A)
ZN  A 227 (-3.1A)
 0.86A 3dtuD-3u9gA:
undetectable		 3dtuD-3u9gA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		5 / 9 PRO A 143
MET A 194
VAL A 198
LEU A 171
ILE A 173
 None
 1.47A 5iepA-3u9gA:
undetectable		 5iepA-3u9gA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 7 THR A  67
THR A  68
ASP A  47
LEU A 193
 None
 1.10A 5jq7B-3u9gA:
undetectable		 5jq7B-3u9gA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3u9g ZINC FINGER
CCCH-TYPE ANTIVIRAL
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 VAL A  64
LEU A  26
LEU A  27
LEU A  40
 None
 0.88A 6f6sA-3u9gA:
undetectable
6f6sB-3u9gA:
undetectable		 6f6sA-3u9gA:
17.03
6f6sB-3u9gA:
16.59