SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3u9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3001_1
(SERUM ALBUMIN)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 LEU A 178
ARG A 134
LEU A 141
HIS A  93
ALA A 129
 None
 1.32A 1hk1A-3u9lA:
undetectable		 1hk1A-3u9lA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3001_1
(SERUM ALBUMIN)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 LEU A 178
ARG A 134
LEU A 141
HIS A  93
ALA A 129
 None
 1.24A 1hk3A-3u9lA:
0.0		 1hk3A-3u9lA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 ASP A  60
LYS A   3
ARG A  87
 None
 0.76A 1ra8A-3u9lA:
undetectable		 1ra8A-3u9lA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 ALA A 245
VAL A 251
GLY A  16
ILE A   8
VAL A  90
 None
 1.22A 2uxpB-3u9lA:
undetectable		 2uxpB-3u9lA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 THR A  19
ILE A   8
GLY A  16
ILE A 144
 None
 0.85A 2y7wC-3u9lA:
undetectable		 2y7wC-3u9lA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 SER A 256
GLY A 257
GLY A 139
GLY A 182
 None
 0.64A 3bogB-3u9lA:
undetectable
3bogD-3u9lA:
undetectable		 3bogB-3u9lA:
undetectable
3bogD-3u9lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 ASN A  94
HIS A  93
VAL A 125
 None
 0.88A 3elzB-3u9lA:
undetectable		 3elzB-3u9lA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 ARG A 135
ASP A  75
GLN A  71
 None
 0.92A 4azsA-3u9lA:
5.4		 4azsA-3u9lA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 ARG A 262
ALA A 247
ASP A 246
ILE A   8
VAL A 265
 None
 1.12A 4l1aA-3u9lA:
undetectable		 4l1aA-3u9lA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 LYS A   4
ILE A   6
ILE A  92
 None
 0.72A 4y0qA-3u9lA:
undetectable		 4y0qA-3u9lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A  90
LEU A 140
VAL A 251
GLY A 253
LEU A  23
 None
 1.09A 5ikrA-3u9lA:
undetectable		 5ikrA-3u9lA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 5 GLY A  14
SER A  12
ARG A  35
GLY A  10
 None
 0.93A 5kprA-3u9lA:
undetectable		 5kprA-3u9lA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 GLY A 224
LYS A 229
ALA A 230
ASN A 220
 None
 0.91A 5mvsB-3u9lA:
5.4		 5mvsB-3u9lA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3u9l 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A  50
VAL A  30
ILE A   8
THR A  19
LEU A  18
 None
 1.29A 5tiwA-3u9lA:
undetectable		 5tiwA-3u9lA:
20.06