SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ua4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_B_DVAB8_0 (GRAMICIDIN A)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	3 / 3	TRP A 130 VAL A 89 TRP A 94	None	1.09A	1c4dA-3ua4A: undetectable 1c4dB-3ua4A: undetectable	1c4dA-3ua4A: 5.08 1c4dB-3ua4A: 5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J7K_A_ACTA701_0 (HOLLIDAY JUNCTION DNA HELICASE RUVB)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 4	GLY A 401 LEU A 400 GLY A 404 ARG A 405	None	0.85A	1j7kA-3ua4A: 2.6	1j7kA-3ua4A: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JTX_A_CVIA200_0 (HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	THR A 407 ILE A 495 ILE A 526 TYR A 447 ILE A 474	None	1.21A	1jtxA-3ua4A: undetectable	1jtxA-3ua4A: 13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MCN_P_DHIP1_0 (IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) PEPTIDE N-ACETYL-D-HIS-L-PRO -NH2)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	3 / 3	PHE A 520 TYR A 447 PRO A 493	None	1.12A	1mcnA-3ua4A: undetectable 1mcnB-3ua4A: undetectable 1mcnP-3ua4A: undetectable	1mcnA-3ua4A: 16.26 1mcnB-3ua4A: 16.26 1mcnP-3ua4A: 1.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MOG_A_RBFA200_1 (DODECIN)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	3 / 3	PHE A 235 TRP A 220 GLU A 261	None	0.88A	1mogA-3ua4A: undetectable	1mogA-3ua4A: 7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_A_THAA1_1 (LIVER CARBOXYLESTERASE I)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 11	LEU A 412 GLY A 415 GLY A 416 LEU A 459 MET A 462	None	1.13A	1mx1A-3ua4A: undetectable	1mx1A-3ua4A: 22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_F_FUAF704_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 11	THR A 525 PHE A 520 LEU A 413 VAL A 449 VAL A 517	None	1.21A	1q23F-3ua4A: undetectable	1q23F-3ua4A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_H_FUAH709_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	THR A 525 PHE A 520 LEU A 413 VAL A 449 VAL A 517	None	1.24A	1q23H-3ua4A: undetectable 1q23I-3ua4A: undetectable	1q23H-3ua4A: 14.77 1q23I-3ua4A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FCN_B_DVAB35_0 (UBIQUITIN)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 6	GLN A 723 GLU A 705 ILE A 722 PRO A 721	None	1.03A	2fcnA-3ua4A: undetectable 2fcnB-3ua4A: undetectable	2fcnA-3ua4A: 8.20 2fcnB-3ua4A: 8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_B_VIAB902_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	ILE A 689 VAL A 536 ALA A 643 ILE A 539 MET A 640	None	1.10A	2h42B-3ua4A: undetectable	2h42B-3ua4A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PIV_A_T3A933_1 (ANDROGEN RECEPTOR)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 9	ILE A 410 GLY A 401 GLU A 440 TYR A 431 GLU A 428	None	1.39A	2pivA-3ua4A: undetectable	2pivA-3ua4A: 15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD2_A_CHDA426_0 (FERROCHELATASE)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 4	LEU A 196 PRO A 197 LEU A 216 ARG A 257	None	1.46A	2qd2A-3ua4A: 2.7	2qd2A-3ua4A: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_0 (NON-STRUCTURAL PROTEIN 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	GLY A 421 GLU A 499 VAL A 517 THR A 518 ILE A 496	None	0.93A	2wa2B-3ua4A: 4.3	2wa2B-3ua4A: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_0 (NON-STRUCTURAL PROTEIN 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	GLY A 421 GLY A 414 VAL A 517 THR A 518 ILE A 496	None	0.91A	2wa2B-3ua4A: 4.3	2wa2B-3ua4A: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YK1_H_NCTH300_1 (FAB FRAGMENT, HEAVY CHAIN FAB FRAGMENT, LIGHT CHAIN)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 10	ILE A 274 GLY A 276 SER A 275 TYR A 321 ALA A 324	None	1.47A	2yk1H-3ua4A: 3.1 2yk1L-3ua4A: 2.5	2yk1H-3ua4A: 15.72 2yk1L-3ua4A: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	GLY A 416 PRO A 419 ASN A 452 ASP A 477 LEU A 500	None	1.22A	2zzmA-3ua4A: 7.8	2zzmA-3ua4A: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H0A_A_9RAA500_2 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	3 / 3	ILE A 629 PHE A 611 HIS A 707	None	0.58A	3h0aA-3ua4A: undetectable	3h0aA-3ua4A: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3003_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 6	ILE A 473 VAL A 471 LEU A 446 LEU A 412	None	0.84A	3kp6A-3ua4A: undetectable 3kp6B-3ua4A: undetectable	3kp6A-3ua4A: 13.01 3kp6B-3ua4A: 13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_1 (YAEB-LIKE PROTEIN RPA0152)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	LEU A 413 LEU A 521 PRO A 493 THR A 524 LEU A 514	None	1.33A	3okxB-3ua4A: undetectable	3okxB-3ua4A: 14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_I_CLMI221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 10	THR A 525 PHE A 520 LEU A 413 VAL A 449 VAL A 517	None	1.16A	3u9fI-3ua4A: undetectable	3u9fI-3ua4A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_J_CLMJ221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	THR A 525 PHE A 520 LEU A 413 VAL A 449 VAL A 517	None	1.16A	3u9fJ-3ua4A: undetectable 3u9fK-3ua4A: undetectable	3u9fJ-3ua4A: 14.77 3u9fK-3ua4A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB504_1 (HEMOLYTIC LECTIN CEL-III)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 5	GLU A 728 GLY A 564 TYR A 580 GLN A 578	None	1.45A	3w9tB-3ua4A: undetectable	3w9tB-3ua4A: 19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_D_W9TD506_1 (HEMOLYTIC LECTIN CEL-III)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 5	GLU A 728 GLY A 564 TYR A 580 GLN A 578	None	1.46A	3w9tD-3ua4A: undetectable	3w9tD-3ua4A: 19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6X_G_HCYG900_2 (GLUCOCORTICOID RECEPTOR)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	3 / 3	LEU A 425 MET A 462 TYR A 447	None	0.84A	4p6xG-3ua4A: undetectable	4p6xG-3ua4A: 16.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	8 / 12	GLY A 414 GLY A 416 ASN A 452 MET A 478 ARG A 479 GLU A 499 LEU A 500 CYH A 513	None	0.70A	4x61A-3ua4A: 19.6	4x61A-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	8 / 12	GLY A 414 GLY A 416 PRO A 419 ASN A 452 MET A 478 GLU A 499 LEU A 500 CYH A 513	None	0.73A	4x61A-3ua4A: 19.6	4x61A-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	7 / 12	GLY A 414 LYS A 451 ASN A 452 ARG A 479 GLU A 499 LEU A 500 CYH A 513	None	0.86A	4x61A-3ua4A: 19.6	4x61A-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	7 / 12	GLY A 414 PRO A 419 LYS A 451 ASN A 452 GLU A 499 LEU A 500 CYH A 513	None	0.91A	4x61A-3ua4A: 19.6	4x61A-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	GLY A 415 LYS A 451 ARG A 479 GLU A 499 CYH A 513	None	1.12A	4x61A-3ua4A: 19.6	4x61A-3ua4A: 34.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2Q_A_ACTA1728_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	3 / 3	ASN A 617 SER A 621 ARG A 625	None	0.89A	5b2qA-3ua4A: 4.6	5b2qA-3ua4A: 18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXE_A_ESTA1000_1 (ESTROGEN RECEPTOR)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 8	LEU A 514 GLU A 512 LEU A 509 ARG A 695	None	1.12A	5dxeA-3ua4A: undetectable	5dxeA-3ua4A: 16.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5EML_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	6 / 12	GLY A 415 LYS A 451 ARG A 479 GLU A 499 LEU A 500 CYH A 513	None	1.00A	5emlA-3ua4A: 38.3	5emlA-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5EML_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	6 / 12	GLY A 415 PRO A 419 LYS A 451 GLU A 499 LEU A 500 CYH A 513	None	1.35A	5emlA-3ua4A: 38.3	5emlA-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5EML_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	8 / 12	GLY A 416 LYS A 451 ASN A 452 MET A 478 ARG A 479 GLU A 499 LEU A 500 CYH A 513	None	0.79A	5emlA-3ua4A: 38.3	5emlA-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5EML_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	8 / 12	GLY A 416 PRO A 419 LYS A 451 ASN A 452 MET A 478 GLU A 499 LEU A 500 CYH A 513	None	0.78A	5emlA-3ua4A: 38.3	5emlA-3ua4A: 34.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5EML_A_SAMA701_1 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 6	TYR A 386 GLY A 414 GLU A 450 ASP A 477	None	0.60A	5emlA-3ua4A: 38.3	5emlA-3ua4A: 34.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I6X_A_8PRA705_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 10	ILE A 183 GLY A 232 PHE A 235 GLY A 228 VAL A 192	None	1.23A	5i6xA-3ua4A: undetectable	5i6xA-3ua4A: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I75_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	ILE A 183 GLY A 232 PHE A 235 GLY A 228 VAL A 192	None	1.13A	5i75A-3ua4A: undetectable	5i75A-3ua4A: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKT_B_TLFB601_0 (PROSTAGLANDIN G/H SYNTHASE 2)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	VAL A 408 VAL A 393 GLY A 395 ALA A 396 LEU A 400	None	1.28A	5iktB-3ua4A: undetectable	5iktB-3ua4A: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_B_PFLB410_1 (PROTON-GATED ION CHANNEL)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 9	PRO A 493 TYR A 411 ILE A 410 THR A 525 ILE A 526	None	1.43A	5mvnB-3ua4A: undetectable	5mvnB-3ua4A: 9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVN_D_PFLD410_1 (PROTON-GATED ION CHANNEL)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 10	PRO A 493 TYR A 411 ILE A 410 THR A 525 ILE A 526	None	1.46A	5mvnD-3ua4A: undetectable	5mvnD-3ua4A: 9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B3A_A_SAMA701_0 (APRA METHYLTRANSFERASE 1)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	6 / 12	GLY A 414 GLY A 416 ASN A 452 ALA A 455 ASP A 477 LEU A 500	None	0.88A	6b3aA-3ua4A: 10.6	6b3aA-3ua4A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B3B_A_SAMA701_0 (APRA METHYLTRANSFERASE 1)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	6 / 12	GLY A 414 GLY A 416 ASN A 452 ALA A 455 ASP A 477 LEU A 500	None	0.89A	6b3bA-3ua4A: 10.4	6b3bA-3ua4A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA607_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 4	GLY A 159 ARG A 417 ASN A 116 LEU A 158	None	1.46A	6b58A-3ua4A: 3.1	6b58A-3ua4A: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CBZ_A_ESTA601_1 (ESTROGEN RECEPTOR)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	4 / 8	LEU A 514 GLU A 512 LEU A 509 ARG A 695	None	1.11A	6cbzA-3ua4A: undetectable	6cbzA-3ua4A: 7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_B_GMJB301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	3ua4	PROTEIN ARGININE N-METHYLTRANSFERASE 5 (Caenorhabditis elegans)	5 / 12	LEU A 245 SER A 270 THR A 308 THR A 240 LEU A 239	None	1.38A	6djzB-3ua4A: undetectable	6djzB-3ua4A: 16.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_B_DVAB8_0","GRAMICIDIN A","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",3,"TRP A 130;VAL A  89;TRP A  94","None","1.09A","1c4dA-3ua4A:undetectable;1c4dB-3ua4A:undetectable","1c4dA-3ua4A:5.08;1c4dB-3ua4A:5.08"],["1J7K_A_ACTA701_0","HOLLIDAY JUNCTION DNA HELICASE RUVB","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"GLY A 401;LEU A 400;GLY A 404;ARG A 405","None","0.85A","1j7kA-3ua4A:2.6","1j7kA-3ua4A:18.75"],["1JTX_A_CVIA200_0","HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"THR A 407;ILE A 495;ILE A 526;TYR A 447;ILE A 474","None","1.21A","1jtxA-3ua4A:undetectable","1jtxA-3ua4A:13.56"],["1MCN_P_DHIP1_0","IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN);PEPTIDE N-ACETYL-D-HIS-L-PRO-NH2","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",3,"PHE A 520;TYR A 447;PRO A 493","None","1.12A","1mcnA-3ua4A:undetectable;1mcnB-3ua4A:undetectable;1mcnP-3ua4A:undetectable","1mcnA-3ua4A:16.26;1mcnB-3ua4A:16.26;1mcnP-3ua4A:1.85"],["1MOG_A_RBFA200_1","DODECIN","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",3,"PHE A 235;TRP A 220;GLU A 261","None","0.88A","1mogA-3ua4A:undetectable","1mogA-3ua4A:7.72"],["1MX1_A_THAA1_1","LIVER CARBOXYLESTERASE I","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"LEU A 412;GLY A 415;GLY A 416;LEU A 459;MET A 462","None","1.13A","1mx1A-3ua4A:undetectable","1mx1A-3ua4A:22.62"],["1Q23_F_FUAF704_1","CHLORAMPHENICOL ACETYLTRANSFERASE","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"THR A 525;PHE A 520;LEU A 413;VAL A 449;VAL A 517","None","1.21A","1q23F-3ua4A:undetectable","1q23F-3ua4A:14.77"],["1Q23_H_FUAH709_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"THR A 525;PHE A 520;LEU A 413;VAL A 449;VAL A 517","None","1.24A","1q23H-3ua4A:undetectable;1q23I-3ua4A:undetectable","1q23H-3ua4A:14.77;1q23I-3ua4A:14.77"],["2FCN_B_DVAB35_0","UBIQUITIN","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"GLN A 723;GLU A 705;ILE A 722;PRO A 721","None","1.03A","2fcnA-3ua4A:undetectable;2fcnB-3ua4A:undetectable","2fcnA-3ua4A:8.20;2fcnB-3ua4A:8.20"],["2H42_B_VIAB902_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"ILE A 689;VAL A 536;ALA A 643;ILE A 539;MET A 640","None","1.10A","2h42B-3ua4A:undetectable","2h42B-3ua4A:19.00"],["2PIV_A_T3A933_1","ANDROGEN RECEPTOR","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"ILE A 410;GLY A 401;GLU A 440;TYR A 431;GLU A 428","None","1.39A","2pivA-3ua4A:undetectable","2pivA-3ua4A:15.55"],["2QD2_A_CHDA426_0","FERROCHELATASE","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"LEU A 196;PRO A 197;LEU A 216;ARG A 257","None","1.46A","2qd2A-3ua4A:2.7","2qd2A-3ua4A:17.89"],["2WA2_B_SAMB1267_0","NON-STRUCTURAL PROTEIN 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"GLY A 421;GLU A 499;VAL A 517;THR A 518;ILE A 496","None","0.93A","2wa2B-3ua4A:4.3","2wa2B-3ua4A:17.48"],["2WA2_B_SAMB1267_0","NON-STRUCTURAL PROTEIN 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"GLY A 421;GLY A 414;VAL A 517;THR A 518;ILE A 496","None","0.91A","2wa2B-3ua4A:4.3","2wa2B-3ua4A:17.48"],["2YK1_H_NCTH300_1","FAB FRAGMENT, HEAVY CHAIN;FAB FRAGMENT, LIGHT CHAIN","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"ILE A 274;GLY A 276;SER A 275;TYR A 321;ALA A 324","None","1.47A","2yk1H-3ua4A:3.1;2yk1L-3ua4A:2.5","2yk1H-3ua4A:15.72;2yk1L-3ua4A:14.73"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"GLY A 416;PRO A 419;ASN A 452;ASP A 477;LEU A 500","None","1.22A","2zzmA-3ua4A:7.8","2zzmA-3ua4A:18.23"],["3H0A_A_9RAA500_2","RETINOIC ACID RECEPTOR RXR-ALPHA","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",3,"ILE A 629;PHE A 611;HIS A 707","None","0.58A","3h0aA-3ua4A:undetectable","3h0aA-3ua4A:16.81"],["3KP6_B_SALB3003_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"ILE A 473;VAL A 471;LEU A 446;LEU A 412","None","0.84A","3kp6A-3ua4A:undetectable;3kp6B-3ua4A:undetectable","3kp6A-3ua4A:13.01;3kp6B-3ua4A:13.01"],["3OKX_B_SAMB201_1","YAEB-LIKE PROTEIN RPA0152","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"LEU A 413;LEU A 521;PRO A 493;THR A 524;LEU A 514","None","1.33A","3okxB-3ua4A:undetectable","3okxB-3ua4A:14.17"],["3U9F_I_CLMI221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"THR A 525;PHE A 520;LEU A 413;VAL A 449;VAL A 517","None","1.16A","3u9fI-3ua4A:undetectable","3u9fI-3ua4A:14.77"],["3U9F_J_CLMJ221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"THR A 525;PHE A 520;LEU A 413;VAL A 449;VAL A 517","None","1.16A","3u9fJ-3ua4A:undetectable;3u9fK-3ua4A:undetectable","3u9fJ-3ua4A:14.77;3u9fK-3ua4A:14.77"],["3W9T_B_W9TB504_1","HEMOLYTIC LECTIN CEL-III","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"GLU A 728;GLY A 564;TYR A 580;GLN A 578","None","1.45A","3w9tB-3ua4A:undetectable","3w9tB-3ua4A:19.97"],["3W9T_D_W9TD506_1","HEMOLYTIC LECTIN CEL-III","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"GLU A 728;GLY A 564;TYR A 580;GLN A 578","None","1.46A","3w9tD-3ua4A:undetectable","3w9tD-3ua4A:19.97"],["4P6X_G_HCYG900_2","GLUCOCORTICOID RECEPTOR","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",3,"LEU A 425;MET A 462;TYR A 447","None","0.84A","4p6xG-3ua4A:undetectable","4p6xG-3ua4A:16.53"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",8,"GLY A 414;GLY A 416;ASN A 452;MET A 478;ARG A 479;GLU A 499;LEU A 500;CYH A 513","None","0.70A","4x61A-3ua4A:19.6","4x61A-3ua4A:34.04"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",8,"GLY A 414;GLY A 416;PRO A 419;ASN A 452;MET A 478;GLU A 499;LEU A 500;CYH A 513","None","0.73A","4x61A-3ua4A:19.6","4x61A-3ua4A:34.04"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",7,"GLY A 414;LYS A 451;ASN A 452;ARG A 479;GLU A 499;LEU A 500;CYH A 513","None","0.86A","4x61A-3ua4A:19.6","4x61A-3ua4A:34.04"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",7,"GLY A 414;PRO A 419;LYS A 451;ASN A 452;GLU A 499;LEU A 500;CYH A 513","None","0.91A","4x61A-3ua4A:19.6","4x61A-3ua4A:34.04"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"GLY A 415;LYS A 451;ARG A 479;GLU A 499;CYH A 513","None","1.12A","4x61A-3ua4A:19.6","4x61A-3ua4A:34.04"],["5B2Q_A_ACTA1728_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",3,"ASN A 617;SER A 621;ARG A 625","None","0.89A","5b2qA-3ua4A:4.6","5b2qA-3ua4A:18.24"],["5DXE_A_ESTA1000_1","ESTROGEN RECEPTOR","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"LEU A 514;GLU A 512;LEU A 509;ARG A 695","None","1.12A","5dxeA-3ua4A:undetectable","5dxeA-3ua4A:16.51"],["5EML_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",6,"GLY A 415;LYS A 451;ARG A 479;GLU A 499;LEU A 500;CYH A 513","None","1.00A","5emlA-3ua4A:38.3","5emlA-3ua4A:34.04"],["5EML_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",6,"GLY A 415;PRO A 419;LYS A 451;GLU A 499;LEU A 500;CYH A 513","None","1.35A","5emlA-3ua4A:38.3","5emlA-3ua4A:34.04"],["5EML_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",8,"GLY A 416;LYS A 451;ASN A 452;MET A 478;ARG A 479;GLU A 499;LEU A 500;CYH A 513","None","0.79A","5emlA-3ua4A:38.3","5emlA-3ua4A:34.04"],["5EML_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",8,"GLY A 416;PRO A 419;LYS A 451;ASN A 452;MET A 478;GLU A 499;LEU A 500;CYH A 513","None","0.78A","5emlA-3ua4A:38.3","5emlA-3ua4A:34.04"],["5EML_A_SAMA701_1","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"TYR A 386;GLY A 414;GLU A 450;ASP A 477","None","0.60A","5emlA-3ua4A:38.3","5emlA-3ua4A:34.04"],["5I6X_A_8PRA705_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"ILE A 183;GLY A 232;PHE A 235;GLY A 228;VAL A 192","None","1.23A","5i6xA-3ua4A:undetectable","5i6xA-3ua4A:20.56"],["5I75_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"ILE A 183;GLY A 232;PHE A 235;GLY A 228;VAL A 192","None","1.13A","5i75A-3ua4A:undetectable","5i75A-3ua4A:20.56"],["5IKT_B_TLFB601_0","PROSTAGLANDIN G\/H SYNTHASE 2","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"VAL A 408;VAL A 393;GLY A 395;ALA A 396;LEU A 400","None","1.28A","5iktB-3ua4A:undetectable","5iktB-3ua4A:21.77"],["5MVN_B_PFLB410_1","PROTON-GATED ION CHANNEL","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"PRO A 493;TYR A 411;ILE A 410;THR A 525;ILE A 526","None","1.43A","5mvnB-3ua4A:undetectable","5mvnB-3ua4A:9.55"],["5MVN_D_PFLD410_1","PROTON-GATED ION CHANNEL","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"PRO A 493;TYR A 411;ILE A 410;THR A 525;ILE A 526","None","1.46A","5mvnD-3ua4A:undetectable","5mvnD-3ua4A:9.55"],["6B3A_A_SAMA701_0","APRA METHYLTRANSFERASE 1","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",6,"GLY A 414;GLY A 416;ASN A 452;ALA A 455;ASP A 477;LEU A 500","None","0.88A","6b3aA-3ua4A:10.6","6b3aA-3ua4A:22.35"],["6B3B_A_SAMA701_0","APRA METHYLTRANSFERASE 1","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",6,"GLY A 414;GLY A 416;ASN A 452;ALA A 455;ASP A 477;LEU A 500","None","0.89A","6b3bA-3ua4A:10.4","6b3bA-3ua4A:22.35"],["6B58_A_ACTA607_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"GLY A 159;ARG A 417;ASN A 116;LEU A 158","None","1.46A","6b58A-3ua4A:3.1","6b58A-3ua4A:21.41"],["6CBZ_A_ESTA601_1","ESTROGEN RECEPTOR","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",4,"LEU A 514;GLU A 512;LEU A 509;ARG A 695","None","1.11A","6cbzA-3ua4A:undetectable","6cbzA-3ua4A:7.13"],["6DJZ_B_GMJB301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","3ua4","PROTEIN ARGININE N-METHYLTRANSFERASE 5","Caenorhabditis elegans",5,"LEU A 245;SER A 270;THR A 308;THR A 240;LEU A 239","None","1.38A","6djzB-3ua4A:undetectable","6djzB-3ua4A:16.21"]]