SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uaj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 ALA B  35
VAL B  15
TRP B  20
 None
 0.84A 1av2C-3uajB:
undetectable
1av2D-3uajB:
undetectable		 1av2C-3uajB:
6.42
1av2D-3uajB:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 PRO B  39
LEU B  41
VAL B 160
TYR B 178
GLY B 159
 None
 1.38A 1lwcA-3uajB:
undetectable		 1lwcA-3uajB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 ALA B  35
VAL B  15
TRP B  20
 None
 0.79A 1w5uC-3uajB:
undetectable
1w5uD-3uajB:
undetectable		 1w5uC-3uajB:
6.42
1w5uD-3uajB:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 PHE B 193
ARG B 167
ASN B 134
 None
 0.76A 1xzxX-3uajB:
undetectable		 1xzxX-3uajB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 TRP B  20
ALA B  35
VAL B  15
 None
 0.84A 2izqA-3uajB:
undetectable
2izqB-3uajB:
undetectable		 2izqA-3uajB:
6.42
2izqB-3uajB:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 HIS B  27
GLU B  26
HIS B 282
 None
 0.89A 3ba0A-3uajB:
undetectable		 3ba0A-3uajB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 ASN B 128
MET B 260
PHE B 213
 None
 0.88A 3g4lD-3uajB:
undetectable		 3g4lD-3uajB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		5 / 10 ILE B  61
SER B 122
GLY B 123
SER B  64
LEU B 218
 None
 0.97A 3ik6B-3uajB:
undetectable
3ik6E-3uajB:
undetectable		 3ik6B-3uajB:
19.26
3ik6E-3uajB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 ALA B  35
VAL B  15
TRP B  20
 None
 0.80A 3l8lA-3uajB:
undetectable
3l8lB-3uajB:
undetectable		 3l8lA-3uajB:
6.42
3l8lB-3uajB:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 ALA B  35
VAL B  15
TRP B  20
 None
 0.79A 3l8lC-3uajB:
undetectable
3l8lD-3uajB:
undetectable		 3l8lC-3uajB:
6.42
3l8lD-3uajB:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		4 / 4 GLU B 368
GLY B 318
HIS B 317
ARG B   9
 None
 1.42A 4r82A-3uajB:
undetectable
4r82B-3uajB:
undetectable		 4r82A-3uajB:
16.86
4r82B-3uajB:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		4 / 7 VAL B 270
THR B 205
LEU B 135
VAL B  53
 None
 0.90A 5e4dA-3uajB:
undetectable
5e4dB-3uajB:
undetectable		 5e4dA-3uajB:
20.05
5e4dB-3uajB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 PRO B  39
LEU B  41
VAL B 160
TYR B 178
GLY B 159
 None
 1.32A 5hbmA-3uajB:
undetectable		 5hbmA-3uajB:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		4 / 7 HIS B 209
ILE B 197
TYR B  59
GLN B 211
 None
 1.30A 5kkzM-3uajB:
2.3
5kkzO-3uajB:
undetectable		 5kkzM-3uajB:
17.54
5kkzO-3uajB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 3uaj ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 LYS B 110
VAL B  96
ASP B  98
 None
 0.70A 6fgdA-3uajB:
undetectable		 6fgdA-3uajB:
20.79