SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uam'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_C_SAMC300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3uam	CHITIN BINDING DOMAIN (Burkholderia pseudomallei)	5 / 12	GLY A 83 GLY A 48 GLY A 71 LEU A 46 GLU A 47	None	0.97A	2oxtC-3uamA: undetectable	2oxtC-3uamA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_A_ACTA1397_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	3uam	CHITIN BINDING DOMAIN (Burkholderia pseudomallei)	3 / 3	PRO A 161 GLY A 164 TYR A 159	None	0.74A	2vouA-3uamA: undetectable	2vouA-3uamA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_A_ROFA901_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3uam	CHITIN BINDING DOMAIN (Burkholderia pseudomallei)	3 / 3	ASP A 39 LEU A 38 GLN A 207	None	0.75A	3g4lA-3uamA: undetectable	3g4lA-3uamA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOD_A_HQEA1173_1 (FMN-BINDING PROTEIN)	3uam	CHITIN BINDING DOMAIN (Burkholderia pseudomallei)	4 / 7	ASP A 96 TRP A 101 ARG A 141 HIS A 100	None	1.23A	3zodA-3uamA: undetectable	3zodA-3uamA: 17.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OXT_C_SAMC300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3uam","CHITIN BINDING DOMAIN","Burkholderia pseudomallei",5,"GLY A  83;GLY A  48;GLY A  71;LEU A  46;GLU A  47","None","0.97A","2oxtC-3uamA:undetectable","2oxtC-3uamA:19.85"],["2VOU_A_ACTA1397_0","2,6-DIHYDROXYPYRIDINE HYDROXYLASE","3uam","CHITIN BINDING DOMAIN","Burkholderia pseudomallei",3,"PRO A 161;GLY A 164;TYR A 159","None","0.74A","2vouA-3uamA:undetectable","2vouA-3uamA:20.62"],["3G4L_A_ROFA901_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","3uam","CHITIN BINDING DOMAIN","Burkholderia pseudomallei",3,"ASP A  39;LEU A  38;GLN A 207","None","0.75A","3g4lA-3uamA:undetectable","3g4lA-3uamA:17.65"],["3ZOD_A_HQEA1173_1","FMN-BINDING PROTEIN","3uam","CHITIN BINDING DOMAIN","Burkholderia pseudomallei",4,"ASP A  96;TRP A 101;ARG A 141;HIS A 100","None","1.23A","3zodA-3uamA:undetectable","3zodA-3uamA:17.29"]]