SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		6 / 12 GLN A  60
ILE A 137
VAL A 219
LEU A  74
ILE A  63
MET A 111
 None
 1.27A 3gwxB-3uanA:
undetectable		 3gwxB-3uanA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		4 / 8 ILE A  62
TYR A 107
LEU A 104
PHE A  93
 None
 0.87A 3rqwI-3uanA:
undetectable
3rqwJ-3uanA:
undetectable		 3rqwI-3uanA:
20.94
3rqwJ-3uanA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		4 / 5 THR A  71
ILE A  63
LYS A 123
GLU A 122
 A3P  A 603 (-2.9A)
None
BDP  A   2 (-3.0A)
None
 1.27A 4ac9C-3uanA:
2.6		 4ac9C-3uanA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		4 / 5 THR A  71
ILE A  63
LYS A 123
GLU A 122
 A3P  A 603 (-2.9A)
None
BDP  A   2 (-3.0A)
None
 1.27A 4acaC-3uanA:
3.9		 4acaC-3uanA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		4 / 5 THR A  71
ILE A  63
LYS A 123
GLU A 122
 A3P  A 603 (-2.9A)
None
BDP  A   2 (-3.0A)
None
 1.38A 4acbC-3uanA:
4.0		 4acbC-3uanA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		5 / 12 VAL A 121
LEU A 239
LEU A  78
LEU A  74
THR A  71
 None
None
None
None
A3P  A 603 (-2.9A)
 0.99A 4k13A-3uanA:
undetectable		 4k13A-3uanA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		6 / 12 VAL A 235
ILE A  63
VAL A 121
LEU A 147
SER A  79
LEU A  75
 None
 1.39A 4m11B-3uanA:
undetectable		 4m11B-3uanA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		4 / 4 ALA A 126
VAL A  66
GLY A  70
THR A  71
 SGN  A   3 (-3.4A)
None
A3P  A 603 (-3.2A)
A3P  A 603 (-2.9A)
 1.08A 4ubeA-3uanA:
2.6		 4ubeA-3uanA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		4 / 5 TYR A 192
LEU A 165
PRO A 176
LEU A 158
 None
 1.43A 5eshA-3uanA:
undetectable		 5eshA-3uanA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		3 / 3 HIS A 290
ASP A 152
HIS A 311
 None
 0.75A 5n1tW-3uanA:
undetectable		 5n1tW-3uanA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		5 / 12 VAL A 235
GLU A 236
PHE A 250
ARG A  72
LEU A  80
 None
None
None
BDP  A   2 (-3.6A)
None
 1.19A 5nd2B-3uanA:
2.4		 5nd2B-3uanA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1
(Mus
musculus) 		5 / 12 VAL A 235
GLU A 236
PHE A 250
ARG A  72
LEU A  80
 None
None
None
BDP  A   2 (-3.6A)
None
 1.06A 5nd4B-3uanA:
undetectable		 5nd4B-3uanA:
21.29