SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uaq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 7 ASN A  65
THR A 181
GLY A 213
TYR A 206
 None
 1.01A 1bu5A-3uaqA:
undetectable		 1bu5A-3uaqA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		3 / 3 THR A 174
GLU A 320
ASP A 160
 None
 0.80A 1nt2A-3uaqA:
undetectable		 1nt2A-3uaqA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		3 / 3 ASP A 182
LEU A  82
HIS A 236
 None
 0.79A 1qknA-3uaqA:
undetectable		 1qknA-3uaqA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 10 PHE A 212
THR A 149
THR A 219
GLY A 153
VAL A 180
 None
 1.27A 2cp4A-3uaqA:
undetectable		 2cp4A-3uaqA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 7 ASN A 172
ASP A 341
THR A 252
GLY A 251
 None
 0.89A 2f6dA-3uaqA:
undetectable		 2f6dA-3uaqA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 5 PHE A 301
PHE A 179
HIS A 236
VAL A 268
 None
 1.09A 2lh6A-3uaqA:
undetectable		 2lh6A-3uaqA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_A_FOLA270_0
(PTERIDINE REDUCTASE)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 11 ARG A 187
PHE A 301
TYR A 271
VAL A 180
MET A 208
 None
 1.38A 3bmcA-3uaqA:
undetectable		 3bmcA-3uaqA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 12 ILE A  61
LEU A  82
PRO A 231
THR A 128
VAL A 180
 None
 1.02A 3dcjA-3uaqA:
undetectable
3dcjB-3uaqA:
undetectable		 3dcjA-3uaqA:
18.00
3dcjB-3uaqA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 12 GLY A 213
GLY A 211
ASP A 214
PHE A 200
ALA A 218
 None
 1.21A 3t7sA-3uaqA:
undetectable		 3t7sA-3uaqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 12 GLY A 213
GLY A 211
ASP A 214
PHE A 200
ALA A 218
 None
 1.25A 3t7sB-3uaqA:
undetectable		 3t7sB-3uaqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 12 GLY A 213
GLY A 211
ASP A 214
PHE A 200
ALA A 218
 None
 1.25A 3t7sD-3uaqA:
undetectable		 3t7sD-3uaqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 12 ALA A 222
GLY A 213
GLY A 211
ASP A 214
GLU A 188
 None
 1.02A 4lg1A-3uaqA:
undetectable		 4lg1A-3uaqA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		3 / 3 LYS A 289
ASN A 328
ASP A 272
 None
 0.79A 4o1eA-3uaqA:
undetectable		 4o1eA-3uaqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 6 GLY A 159
TYR A 157
ALA A 322
ARG A 281
 None
 1.25A 4yshB-3uaqA:
undetectable		 4yshB-3uaqA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		3 / 3 GLU A  78
HIS A  75
ASP A 214
 None
 0.73A 5c0oG-3uaqA:
undetectable		 5c0oG-3uaqA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 6 GLU A 320
ALA A 238
LEU A 253
TYR A 157
 None
 1.09A 5igiA-3uaqA:
undetectable		 5igiA-3uaqA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 8 ILE A 277
THR A 163
ALA A 318
LEU A 321
 None
 0.74A 5og9A-3uaqA:
undetectable		 5og9A-3uaqA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 6 ASN A 172
ALA A 171
ASP A 341
TYR A 173
 None
 1.03A 5umd2-3uaqA:
undetectable
5umdF-3uaqA:
undetectable		 5umd2-3uaqA:
11.44
5umdF-3uaqA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		4 / 6 PHE A 313
GLY A 315
THR A 163
ASN A 161
 None
 0.89A 5x24A-3uaqA:
undetectable		 5x24A-3uaqA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3uaq LBPB B-LOBE
(Moraxella
bovis) 		5 / 12 TYR A 156
LEU A  55
GLY A  56
VAL A 121
ASP A 160
 None
 1.11A 6bxlB-3uaqA:
undetectable		 6bxlB-3uaqA:
21.34