SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uar'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		5 / 11 LEU A  70
LEU A  73
ALA A  74
LEU A  82
LEU A  94
 None
 1.25A 1g50A-3uarA:
undetectable		 1g50A-3uarA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		5 / 10 LEU A  70
LEU A  73
ALA A  74
LEU A  82
LEU A  94
 None
 1.26A 1gwrA-3uarA:
undetectable		 1gwrA-3uarA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		5 / 12 LEU A  18
ALA A 195
GLU A 199
LEU A  12
LEU A  70
 None
 1.05A 1s9pA-3uarA:
undetectable		 1s9pA-3uarA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		3 / 3 GLU A  90
SER A 153
VAL A 154
 None
 0.75A 3eeoA-3uarA:
undetectable		 3eeoA-3uarA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		4 / 6 VAL A  17
ALA A  74
LEU A  94
LEU A  98
 None
 0.76A 4o0uA-3uarA:
undetectable		 4o0uA-3uarA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		4 / 6 VAL A 162
LEU A 159
CYH A 166
LEU A 133
 None
 1.25A 5hrqB-3uarA:
undetectable
5hrqI-3uarA:
undetectable
5hrqJ-3uarA:
undetectable		 5hrqB-3uarA:
11.04
5hrqI-3uarA:
6.88
5hrqJ-3uarA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		4 / 6 ALA A 155
LEU A 159
TYR A 182
SER A 153
 None
 1.15A 5phhA-3uarA:
undetectable		 5phhA-3uarA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		6 / 12 LEU A  70
LEU A  73
ALA A  74
LEU A  82
ILE A 101
LEU A  94
 None
 1.33A 5toaA-3uarA:
undetectable		 5toaA-3uarA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3uar GLUTATHIONE
S-TRANSFERASE
(Methylococcus
capsulatus) 		4 / 7 ILE A  69
LEU A  55
MET A   1
LEU A  57
 None
 0.83A 5u4sA-3uarA:
undetectable		 5u4sA-3uarA:
23.57