SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 7 ILE A 845
PRO A 839
PHE A 836
ALA A 864
 None
 1.10A 1oniG-3uatA:
undetectable
1oniI-3uatA:
undetectable		 1oniG-3uatA:
20.27
1oniI-3uatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 5 VAL A 734
ASN A 735
VAL A 891
ILE A 837
 None
 0.99A 1z2bC-3uatA:
undetectable		 1z2bC-3uatA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 12 LEU A 588
PHE A 608
GLN A 826
LEU A 583
VAL A 614
 None
 0.98A 2qd4A-3uatA:
undetectable		 2qd4A-3uatA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 12 LEU A 588
PHE A 608
GLN A 826
LEU A 583
VAL A 614
 None
 1.02A 2qd4B-3uatA:
undetectable		 2qd4B-3uatA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 5 LEU A 727
GLY A 728
PHE A 836
PHE A 875
 None
 1.17A 3smtA-3uatA:
undetectable		 3smtA-3uatA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 5 PHE A 871
PHE A 875
LEU A 825
PRO A 723
 None
 1.31A 4o8zA-3uatA:
undetectable		 4o8zA-3uatA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 7 ARG A 758
TYR A 796
GLU A 761
ASP A 766
 None
 0.96A 4zz8A-3uatA:
undetectable		 4zz8A-3uatA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 12 ALA A 587
ASP A 596
PRO A 641
SER A 709
GLU A 647
 None
 1.12A 5hfjD-3uatA:
undetectable		 5hfjD-3uatA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 12 ALA A 587
ASP A 596
PRO A 641
SER A 709
GLU A 647
 None
 1.14A 5hfjG-3uatA:
undetectable		 5hfjG-3uatA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 12 GLY A 603
GLY A 638
ASN A 605
ASP A 592
THR A 594
 None
 1.10A 5kpcB-3uatA:
undetectable		 5kpcB-3uatA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		5 / 10 ILE A 894
ILE A 833
VAL A 891
ASN A 735
ILE A 726
 None
 1.31A 5lg3F-3uatA:
undetectable		 5lg3F-3uatA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3uat DISKS LARGE HOMOLOG
1
(Rattus
norvegicus) 		4 / 7 ILE A 887
GLN A 890
VAL A 891
ILE A 726
 None
 0.75A 6cduF-3uatA:
undetectable
6cduG-3uatA:
undetectable		 6cduF-3uatA:
21.10
6cduG-3uatA:
21.10