SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uav'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		4 / 6 LYS A 135
LYS A 136
ASP A 139
ALA A 140
 None
 0.23A 1iwhA-3uavA:
undetectable		 1iwhA-3uavA:
24.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 10 ARG A  87
THR A  90
VAL A 178
GLU A 179
MET A 180
GLU A 181
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
 0.35A 1jdvA-3uavA:
34.7
1jdvD-3uavA:
18.0		 1jdvA-3uavA:
36.25
1jdvD-3uavA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 10 ARG A  87
THR A  90
VAL A 178
GLU A 179
MET A 180
GLU A 181
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
 0.36A 1jdvB-3uavA:
17.8
1jdvC-3uavA:
34.6		 1jdvB-3uavA:
36.25
1jdvC-3uavA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 10 ARG A  87
THR A  90
VAL A 178
GLU A 179
MET A 180
GLU A 181
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
 0.33A 1jdvA-3uavA:
34.7
1jdvD-3uavA:
18.0		 1jdvA-3uavA:
36.25
1jdvD-3uavA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 12 ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.54A 1jdvE-3uavA:
34.7
1jdvF-3uavA:
34.7		 1jdvE-3uavA:
36.25
1jdvF-3uavA:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8I_A_H4BA902_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		4 / 5 SER A  68
MET A  64
ARG A  24
ILE A  69
 None
None
SO4  A 236 (-2.6A)
None
 1.45A 1m8iA-3uavA:
0.0		 1m8iA-3uavA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
SO4  A 236 ( 4.4A)
None
 1.19A 1odiA-3uavA:
26.3		 1odiA-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.45A 1odiA-3uavA:
26.3		 1odiA-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
SO4  A 236 ( 4.4A)
None
 1.15A 1odiB-3uavA:
36.1		 1odiB-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.42A 1odiB-3uavA:
36.1		 1odiB-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
SO4  A 236 ( 4.4A)
None
 1.13A 1odiC-3uavA:
36.3		 1odiC-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.48A 1odiC-3uavA:
36.3		 1odiC-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
SO4  A 236 ( 4.4A)
None
 1.17A 1odiD-3uavA:
36.1		 1odiD-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.46A 1odiD-3uavA:
36.1		 1odiD-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
SO4  A 236 ( 4.4A)
None
 1.17A 1odiE-3uavA:
36.2		 1odiE-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 11 ARG A  87
THR A  90
MET A  64
GLU A 181
SER A 203
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
SO4  A 236 ( 4.4A)
None
 1.42A 1odiE-3uavA:
36.2		 1odiE-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.38A 1odiE-3uavA:
36.2		 1odiE-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  87
THR A  90
GLY A  92
GLU A 179
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
SO4  A 236 ( 4.4A)
None
 1.20A 1odiF-3uavA:
36.2		 1odiF-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.43A 1odiF-3uavA:
36.2		 1odiF-3uavA:
40.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
None
 0.54A 1pk7A-3uavA:
37.0		 1pk7A-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.58A 1pk7C-3uavA:
37.6		 1pk7C-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.50A 1pk9A-3uavA:
36.9		 1pk9A-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 9 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
None
 0.53A 1pk9B-3uavA:
37.4		 1pk9B-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.44A 1pk9C-3uavA:
36.5		 1pk9C-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.54A 1pk9C-3uavA:
36.5		 1pk9C-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
None
 1.37A 1pw7A-3uavA:
37.0		 1pw7A-3uavA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
None
 0.32A 1pw7A-3uavA:
37.0		 1pw7A-3uavA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 10 MET A  64
ARG A  87
GLY A  92
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
None
 0.48A 1pw7A-3uavA:
37.0		 1pw7A-3uavA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 9 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
SO4  A 236 ( 4.4A)
None
 1.34A 1pw7B-3uavA:
37.4		 1pw7B-3uavA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 9 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.48A 1pw7B-3uavA:
37.4		 1pw7B-3uavA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 9 MET A  64
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.49A 1pw7C-3uavA:
37.4		 1pw7C-3uavA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 9 MET A  64
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.61A 1pw7C-3uavA:
37.4		 1pw7C-3uavA:
55.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		4 / 5 LYS A  26
LEU A  46
ALA A  29
SER A  58
 None
 1.03A 1tt6B-3uavA:
undetectable		 1tt6B-3uavA:
23.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 GLY A  92
VAL A 178
GLU A 179
GLU A 181
ILE A 206
ARG A  24
 None
None
None
SO4  A 236 ( 4.4A)
None
SO4  A 236 (-2.6A)
 1.40A 1vhwA-3uavA:
37.7
1vhwD-3uavA:
37.8		 1vhwA-3uavA:
55.00
1vhwD-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.41A 1vhwA-3uavA:
37.7
1vhwD-3uavA:
37.8		 1vhwA-3uavA:
55.00
1vhwD-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.46A 1vhwA-3uavA:
37.7
1vhwD-3uavA:
37.8		 1vhwA-3uavA:
55.00
1vhwD-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 9 MET A  64
ARG A  87
GLY A  92
VAL A 178
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
 0.44A 1vhwB-3uavA:
37.8
1vhwF-3uavA:
37.7		 1vhwB-3uavA:
55.00
1vhwF-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 GLY A  92
VAL A 178
GLU A 179
GLU A 181
ILE A 206
ARG A  24
 None
None
None
SO4  A 236 ( 4.4A)
None
SO4  A 236 (-2.6A)
 1.44A 1vhwC-3uavA:
37.8
1vhwE-3uavA:
37.9		 1vhwC-3uavA:
55.00
1vhwE-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.48A 1vhwC-3uavA:
37.8
1vhwE-3uavA:
37.9		 1vhwC-3uavA:
55.00
1vhwE-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.46A 1vhwC-3uavA:
37.8
1vhwE-3uavA:
37.9		 1vhwC-3uavA:
55.00
1vhwE-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  24
GLY A  92
VAL A 178
GLU A 179
GLU A 181
ILE A 206
 SO4  A 236 (-2.6A)
None
None
None
SO4  A 236 ( 4.4A)
None
 1.42A 1vhwA-3uavA:
37.7
1vhwD-3uavA:
37.8		 1vhwA-3uavA:
55.00
1vhwD-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.45A 1vhwA-3uavA:
37.7
1vhwD-3uavA:
37.8		 1vhwA-3uavA:
55.00
1vhwD-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.45A 1vhwA-3uavA:
37.7
1vhwD-3uavA:
37.8		 1vhwA-3uavA:
55.00
1vhwD-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ARG A  24
GLY A  92
VAL A 178
GLU A 179
GLU A 181
ILE A 206
 SO4  A 236 (-2.6A)
None
None
None
SO4  A 236 ( 4.4A)
None
 1.40A 1vhwC-3uavA:
37.8
1vhwE-3uavA:
37.9		 1vhwC-3uavA:
55.00
1vhwE-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.41A 1vhwC-3uavA:
37.8
1vhwE-3uavA:
37.9		 1vhwC-3uavA:
55.00
1vhwE-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.46A 1vhwC-3uavA:
37.8
1vhwE-3uavA:
37.9		 1vhwC-3uavA:
55.00
1vhwE-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 10 ARG A  24
GLY A  92
VAL A 178
GLU A 179
GLU A 181
 SO4  A 236 (-2.6A)
None
None
None
SO4  A 236 ( 4.4A)
 1.32A 1vhwB-3uavA:
37.8
1vhwF-3uavA:
37.7		 1vhwB-3uavA:
55.00
1vhwF-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 10 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.45A 1vhwB-3uavA:
37.8
1vhwF-3uavA:
37.7		 1vhwB-3uavA:
55.00
1vhwF-3uavA:
55.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 10 ARG A  87
THR A  90
MET A  64
GLU A 181
SER A 203
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
SO4  A 236 ( 4.4A)
None
 1.49A 1z35A-3uavA:
37.4		 1z35A-3uavA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 10 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.56A 1z35A-3uavA:
37.4		 1z35A-3uavA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 9 ARG A  87
THR A  90
MET A  64
GLU A 181
SER A 203
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
SO4  A 236 ( 4.4A)
None
 1.49A 1z37A-3uavA:
37.4		 1z37A-3uavA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 9 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.53A 1z37A-3uavA:
37.4		 1z37A-3uavA:
47.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 11 GLY A  92
VAL A 178
GLU A 179
GLU A 181
ARG A  24
 None
None
None
SO4  A 236 ( 4.4A)
SO4  A 236 (-2.6A)
 1.50A 2ac7A-3uavA:
42.4
2ac7B-3uavA:
42.5		 2ac7A-3uavA:
100.00
2ac7B-3uavA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.22A 2ac7A-3uavA:
42.4
2ac7B-3uavA:
42.5		 2ac7A-3uavA:
100.00
2ac7B-3uavA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 11 ARG A  24
GLY A  92
VAL A 178
GLU A 179
GLU A 181
 SO4  A 236 (-2.6A)
None
None
None
SO4  A 236 ( 4.4A)
 1.49A 2ac7A-3uavA:
42.4
2ac7B-3uavA:
42.5		 2ac7A-3uavA:
100.00
2ac7B-3uavA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.22A 2ac7A-3uavA:
42.4
2ac7B-3uavA:
42.5		 2ac7A-3uavA:
100.00
2ac7B-3uavA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		4 / 6 LEU A  33
LEU A 229
PRO A  19
VAL A  88
 None
 1.13A 2dqyC-3uavA:
undetectable		 2dqyC-3uavA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 11 LEU A  17
ALA A 231
ALA A 232
VAL A  59
LEU A  33
 None
 1.32A 3bszE-3uavA:
undetectable		 3bszE-3uavA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 SO4  A 236 (-3.0A)
None
None
None
None
 0.43A 3kvrA-3uavA:
24.4		 3kvrA-3uavA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 10 THR A  90
GLY A  92
PHE A 159
GLU A 179
MET A 180
 SO4  A 236 (-3.0A)
None
None
None
None
 0.44A 3kvrB-3uavA:
24.4		 3kvrB-3uavA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 ILE A  69
ALA A 156
THR A 111
ALA A 109
ALA A 184
THR A 183
 None
 1.22A 3mdtB-3uavA:
undetectable		 3mdtB-3uavA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 LEU A  17
ALA A 231
GLY A 141
VAL A  88
ILE A  86
 None
 0.90A 3nu3A-3uavA:
undetectable		 3nu3A-3uavA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 LEU A  76
GLY A  47
GLY A  50
VAL A  82
ILE A  12
 None
 1.00A 3nu3A-3uavA:
undetectable		 3nu3A-3uavA:
19.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 9 MET A  64
ARG A  87
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
 0.48A 3u40A-3uavA:
36.0
3u40F-3uavA:
15.4		 3u40A-3uavA:
45.27
3u40F-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 10 MET A  64
ARG A  87
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
 0.47A 3u40B-3uavA:
17.9
3u40C-3uavA:
18.6		 3u40B-3uavA:
45.27
3u40C-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 ARG A  24
GLY A  92
VAL A 178
GLU A 179
GLU A 181
 SO4  A 236 (-2.6A)
None
None
None
SO4  A 236 ( 4.4A)
 1.39A 3u40B-3uavA:
17.9
3u40C-3uavA:
18.6		 3u40B-3uavA:
45.27
3u40C-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 12 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.40A 3u40B-3uavA:
17.9
3u40C-3uavA:
18.6		 3u40B-3uavA:
45.27
3u40C-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 11 GLY A  92
VAL A 178
GLU A 179
GLU A 181
ARG A  24
 None
None
None
SO4  A 236 ( 4.4A)
SO4  A 236 (-2.6A)
 1.43A 3u40D-3uavA:
36.2
3u40E-3uavA:
35.5		 3u40D-3uavA:
45.27
3u40E-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.38A 3u40D-3uavA:
36.2
3u40E-3uavA:
35.5		 3u40D-3uavA:
45.27
3u40E-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 ARG A  24
GLY A  92
VAL A 178
GLU A 179
GLU A 181
 SO4  A 236 (-2.6A)
None
None
None
SO4  A 236 ( 4.4A)
 1.38A 3u40D-3uavA:
36.2
3u40E-3uavA:
35.5		 3u40D-3uavA:
45.27
3u40E-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 12 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.44A 3u40D-3uavA:
36.2
3u40E-3uavA:
35.5		 3u40D-3uavA:
45.27
3u40E-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 10 MET A  64
ARG A  87
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
SO4  A 236 ( 4.4A)
 0.45A 3u40A-3uavA:
36.0
3u40F-3uavA:
15.4		 3u40A-3uavA:
45.27
3u40F-3uavA:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.37A 3uawA-3uavA:
43.0		 3uawA-3uavA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		10 / 11 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.35A 3uawA-3uavA:
43.0		 3uawA-3uavA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 10 ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A  94
 SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 1.41A 3uayA-3uavA:
43.8		 3uayA-3uavA:
99.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 10 MET A  64
ARG A  87
THR A  90
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
SO4  A 236 (-3.0A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.28A 3uayA-3uavA:
43.8		 3uayA-3uavA:
99.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.44A 4d9hA-3uavA:
39.1		 4d9hA-3uavA:
71.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 9 MET A  64
GLY A  92
VAL A 178
MET A 180
GLU A 181
 None
None
None
None
SO4  A 236 ( 4.4A)
 0.19A 4da6A-3uavA:
39.0		 4da6A-3uavA:
71.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 10 MET A  64
ARG A  87
GLY A  92
ALA A 156
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.52A 4da7A-3uavA:
39.2		 4da7A-3uavA:
71.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 11 MET A  64
ARG A  87
GLU A 179
MET A 180
GLU A 181
SER A 203
 None
SO4  A 236 (-2.7A)
None
None
SO4  A 236 ( 4.4A)
None
 0.65A 4danA-3uavA:
38.8		 4danA-3uavA:
71.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		7 / 11 MET A  64
ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.28A 4danA-3uavA:
38.8		 4danA-3uavA:
71.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 ARG A  87
GLU A 179
MET A 180
GLU A 181
SER A 203
 SO4  A 236 (-2.7A)
None
None
SO4  A 236 ( 4.4A)
None
 0.78A 4danA-3uavA:
38.8
4danB-3uavA:
38.8		 4danA-3uavA:
71.37
4danB-3uavA:
71.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		6 / 12 ARG A  87
GLY A  92
VAL A 178
GLU A 179
MET A 180
GLU A 181
 SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
 0.30A 4danA-3uavA:
38.8
4danB-3uavA:
38.8		 4danA-3uavA:
71.37
4danB-3uavA:
71.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 GLY A  65
GLU A 181
GLY A  63
GLY A  20
SER A  68
 None
SO4  A 236 ( 4.4A)
None
SO4  A 236 (-3.3A)
None
 1.00A 4uciA-3uavA:
undetectable		 4uciA-3uavA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 GLY A  65
GLU A 181
GLY A  63
GLY A  20
SER A  68
 None
SO4  A 236 ( 4.4A)
None
SO4  A 236 (-3.3A)
None
 1.01A 4uciB-3uavA:
undetectable		 4uciB-3uavA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 12 GLY A  65
GLU A 181
GLY A  63
GLY A  20
SER A  68
 None
SO4  A 236 ( 4.4A)
None
SO4  A 236 (-3.3A)
None
 0.93A 4uckA-3uavA:
undetectable		 4uckA-3uavA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		5 / 11 MET A 224
ALA A 231
LEU A 133
LEU A 134
LEU A  17
 None
 1.18A 5dxgB-3uavA:
undetectable		 5dxgB-3uavA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		4 / 7 ILE A  28
ILE A  86
ILE A 227
PHE A 221
 None
 0.81A 5fukA-3uavA:
undetectable
5fukB-3uavA:
undetectable		 5fukA-3uavA:
21.89
5fukB-3uavA:
21.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		8 / 9 MET A  64
ARG A  87
GLY A  92
ALA A 156
VAL A 178
MET A 180
GLU A 181
ILE A 206
 None
SO4  A 236 (-2.7A)
None
None
None
None
SO4  A 236 ( 4.4A)
None
 0.46A 5i3cA-3uavA:
38.0		 5i3cA-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 10 MET A  64
GLY A  92
ALA A 156
VAL A 178
GLU A 179
MET A 180
GLU A 181
ASP A 204
ILE A 206
 None
None
None
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.54A 5i3cB-3uavA:
37.8		 5i3cB-3uavA:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		9 / 11 MET A  64
GLY A  92
ALA A 156
VAL A 178
GLU A 179
MET A 180
GLU A 181
SER A 203
ILE A 206
 None
None
None
None
None
None
SO4  A 236 ( 4.4A)
None
None
 0.56A 5i3cC-3uavA:
37.8		 5i3cC-3uavA:
55.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3uav PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Bacillus
cereus) 		4 / 7 ILE A  16
GLN A  60
GLU A  75
VAL A  82
 None
None
GOL  A 238 (-4.8A)
None
 1.17A 6j20A-3uavA:
undetectable		 6j20A-3uavA:
17.00