SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ub9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3ub9 CHEMORECEPTOR TLPB
(Helicobacter
pylori) 		4 / 6 ASP A 114
VAL A 116
PHE A 113
THR A 183
 NHY  A 301 (-2.6A)
NHY  A 301 (-3.9A)
None
NHY  A 301 ( 4.3A)
 1.11A 2q6oB-3ub9A:
undetectable		 2q6oB-3ub9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ub9 CHEMORECEPTOR TLPB
(Helicobacter
pylori) 		4 / 5 GLY A 139
TYR A 169
SER A 170
GLU A 142
 None
 1.33A 4xueA-3ub9A:
undetectable		 4xueA-3ub9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3ub9 CHEMORECEPTOR TLPB
(Helicobacter
pylori) 		5 / 12 TYR A 169
PHE A 167
TYR A 150
PHE A  90
ILE A  65
 None
 1.22A 6aybA-3ub9A:
undetectable		 6aybA-3ub9A:
17.66