SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ubg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XPV_A_MIYA1209_1 (TETRACYCLINE REPRESSOR PROTEIN CLASS D)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	5 / 12	PHE A 714 HIS A 721 ARG A 745 THR A 696 ILE A 660	None	1.48A	2xpvA-3ubgA: undetectable	2xpvA-3ubgA: 23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_C_MTXC164_2 (DIHYDROFOLATE REDUCTASE)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	4 / 4	ILE A 673 ARG A 745 ILE A 671 THR A 728	None	1.09A	3ia4C-3ubgA: undetectable	3ia4C-3ubgA: 19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	5 / 9	TYR A 685 ILE A 699 ILE A 705 VAL A 727 ILE A 671	None	1.32A	3p4wA-3ubgA: undetectable	3p4wA-3ubgA: 24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTS_A_SAMA301_0 (DNA ADENINE METHYLASE)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	5 / 12	GLY A 625 ASP A 622 ILE A 578 ASN A 577 TYR A 542	None CA A 901 (-3.5A) None None None	1.17A	4rtsA-3ubgA: undetectable	4rtsA-3ubgA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_A_PFLA412_1 (PROTON-GATED ION CHANNEL)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	5 / 10	TYR A 685 ILE A 699 ILE A 705 VAL A 727 ILE A 671	None	1.28A	5mzrA-3ubgA: undetectable	5mzrA-3ubgA: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_C_PFLC409_1 (PROTON-GATED ION CHANNEL)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	5 / 10	TYR A 685 ILE A 699 ILE A 705 VAL A 727 ILE A 671	None	1.28A	5mzrC-3ubgA: undetectable	5mzrC-3ubgA: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_D_PFLD410_1 (PROTON-GATED ION CHANNEL)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	5 / 9	TYR A 685 ILE A 699 ILE A 705 VAL A 727 ILE A 671	None	1.26A	5mzrD-3ubgA: undetectable	5mzrD-3ubgA: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_B_SAMB501_1 (PEPTIDE N-METHYLTRANSFERASE)	3ubg	NEURAL-CADHERIN (Drosophila melanogaster)	4 / 4	GLY A 598 ALA A 569 MET A 550 THR A 635	None	1.45A	5n0sB-3ubgA: undetectable	5n0sB-3ubgA: 23.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XPV_A_MIYA1209_1","TETRACYCLINE REPRESSOR PROTEIN CLASS D","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",5,"PHE A 714;HIS A 721;ARG A 745;THR A 696;ILE A 660","None","1.48A","2xpvA-3ubgA:undetectable","2xpvA-3ubgA:23.22"],["3IA4_C_MTXC164_2","DIHYDROFOLATE REDUCTASE","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",4,"ILE A 673;ARG A 745;ILE A 671;THR A 728","None","1.09A","3ia4C-3ubgA:undetectable","3ia4C-3ubgA:19.61"],["3P4W_A_DSFA319_1","GLR4197 PROTEIN","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",5,"TYR A 685;ILE A 699;ILE A 705;VAL A 727;ILE A 671","None","1.32A","3p4wA-3ubgA:undetectable","3p4wA-3ubgA:24.51"],["4RTS_A_SAMA301_0","DNA ADENINE METHYLASE","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",5,"GLY A 625;ASP A 622;ILE A 578;ASN A 577;TYR A 542","None; CA A 901 (-3.5A);None;None;None","1.17A","4rtsA-3ubgA:undetectable","4rtsA-3ubgA:21.99"],["5MZR_A_PFLA412_1","PROTON-GATED ION CHANNEL","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",5,"TYR A 685;ILE A 699;ILE A 705;VAL A 727;ILE A 671","None","1.28A","5mzrA-3ubgA:undetectable","5mzrA-3ubgA:13.97"],["5MZR_C_PFLC409_1","PROTON-GATED ION CHANNEL","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",5,"TYR A 685;ILE A 699;ILE A 705;VAL A 727;ILE A 671","None","1.28A","5mzrC-3ubgA:undetectable","5mzrC-3ubgA:13.97"],["5MZR_D_PFLD410_1","PROTON-GATED ION CHANNEL","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",5,"TYR A 685;ILE A 699;ILE A 705;VAL A 727;ILE A 671","None","1.26A","5mzrD-3ubgA:undetectable","5mzrD-3ubgA:13.97"],["5N0S_B_SAMB501_1","PEPTIDE N-METHYLTRANSFERASE","3ubg","NEURAL-CADHERIN","Drosophila melanogaster",4,"GLY A 598;ALA A 569;MET A 550;THR A 635","None","1.45A","5n0sB-3ubgA:undetectable","5n0sB-3ubgA:23.96"]]