SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ubr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 ASP A  44
GLY A 164
GLU A  36
ARG A  38
TYR A 470
 None
 1.29A 1agmA-3ubrA:
undetectable		 1agmA-3ubrA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 ASP A  44
GLY A 164
GLU A  36
ARG A  38
TYR A 470
 None
 1.29A 1agmA-3ubrA:
undetectable		 1agmA-3ubrA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 10 ALA A 347
GLU A 346
LEU A 409
MET A 252
LEU A 364
 None
 1.43A 1qkuA-3ubrA:
undetectable		 1qkuA-3ubrA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 10 ALA A 347
GLU A 346
LEU A 409
MET A 252
LEU A 364
 None
 1.43A 1qkuB-3ubrA:
undetectable		 1qkuB-3ubrA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 10 ALA A 347
GLU A 346
LEU A 409
MET A 252
LEU A 364
 None
 1.43A 1qkuC-3ubrA:
undetectable		 1qkuC-3ubrA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		3 / 3 ASP A 404
THR A 250
PRO A 251
 None
 0.68A 2pynB-3ubrA:
undetectable		 2pynB-3ubrA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		3 / 3 ASP A 404
THR A 250
PRO A 251
 None
 0.67A 2q64B-3ubrA:
undetectable		 2q64B-3ubrA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		3 / 3 ASP A 404
THR A 250
PRO A 251
 None
 0.70A 2qakB-3ubrA:
undetectable		 2qakB-3ubrA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 9 LEU A  75
LEU A 247
ALA A  82
LEU A 437
ALA A 433
 None
 1.11A 2vcvD-3ubrA:
undetectable		 2vcvD-3ubrA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.06A 3eeyA-3ubrA:
undetectable		 3eeyA-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.08A 3eeyB-3ubrA:
undetectable		 3eeyB-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.09A 3eeyC-3ubrA:
undetectable		 3eeyC-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.11A 3eeyD-3ubrA:
undetectable		 3eeyD-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.08A 3eeyF-3ubrA:
undetectable		 3eeyF-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.09A 3eeyH-3ubrA:
undetectable		 3eeyH-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.09A 3eeyI-3ubrA:
undetectable		 3eeyI-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 THR A 154
GLY A 156
ASP A 126
GLY A  90
ASN A 153
 None
HEC  A 472 (-4.0A)
None
HEC  A 473 ( 4.4A)
None
 1.07A 3eeyJ-3ubrA:
undetectable		 3eeyJ-3ubrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_1
(METHYLTRANSFERASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 9 GLY A 266
GLU A 389
PRO A 388
ASN A 271
HIS A 268
 None
HEC  A 475 ( 4.5A)
None
HEC  A 475 (-3.7A)
HEC  A 474 ( 2.9A)
 1.31A 3ndiA-3ubrA:
0.0		 3ndiA-3ubrA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 VAL A  95
VAL A  98
ARG A  99
LYS A 143
 None
HEC  A 471 ( 4.7A)
None
None
 1.17A 3rv5A-3ubrA:
undetectable
3rv5B-3ubrA:
undetectable		 3rv5A-3ubrA:
13.85
3rv5B-3ubrA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		3 / 3 ASP A 404
THR A 250
PRO A 251
 None
 0.59A 3tkgD-3ubrA:
undetectable		 3tkgD-3ubrA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 8 TRP A 372
ARG A 373
LEU A 376
GLU A 390
 None
 1.29A 3zmdA-3ubrA:
undetectable
3zmdB-3ubrA:
undetectable		 3zmdA-3ubrA:
16.89
3zmdB-3ubrA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 10 SER A  32
ASP A 126
ARG A 169
GLU A  40
ASP A 159
 None
None
None
None
HEC  A 473 (-3.7A)
 1.47A 4fevA-3ubrA:
0.0		 4fevA-3ubrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 TYR A  79
TYR A 235
GLU A 205
GLN A 256
 None
None
CA  A 476 (-2.4A)
CA  A 476 (-3.2A)
 1.22A 4qztB-3ubrA:
undetectable		 4qztB-3ubrA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 TYR A 235
GLU A 205
LEU A 253
GLN A 256
 None
CA  A 476 (-2.4A)
None
CA  A 476 (-3.2A)
 0.88A 4qztB-3ubrA:
undetectable		 4qztB-3ubrA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 GLY A 105
ALA A 106
GLY A 113
PRO A 114
 None
 0.87A 4u9uA-3ubrA:
undetectable		 4u9uA-3ubrA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 GLY A 105
ALA A 106
GLY A 113
PRO A 114
 None
 0.88A 4u9uB-3ubrA:
undetectable		 4u9uB-3ubrA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		3 / 3 GLU A  40
LYS A  43
ASN A  39
 None
 0.61A 4y1dA-3ubrA:
undetectable
4y1dD-3ubrA:
undetectable		 4y1dA-3ubrA:
16.79
4y1dD-3ubrA:
2.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 LEU A  75
ALA A  77
ILE A 427
ALA A 433
ILE A 424
 None
 1.20A 5eypB-3ubrA:
undetectable		 5eypB-3ubrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		3 / 3 ARG A 466
THR A 152
ASP A 126
 None
 0.76A 5g5gA-3ubrA:
undetectable
5g5gB-3ubrA:
undetectable		 5g5gA-3ubrA:
19.95
5g5gB-3ubrA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		6 / 12 LEU A  75
LEU A 437
ALA A  77
ILE A 427
ALA A 433
ILE A 424
 None
 1.48A 5nm5B-3ubrA:
undetectable		 5nm5B-3ubrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 ASP A  44
GLY A 164
GLU A  36
ARG A  38
TYR A 470
 None
 1.17A 6fhwA-3ubrA:
undetectable		 6fhwA-3ubrA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		5 / 12 ASP A  44
GLY A 164
GLU A  36
ARG A  38
TYR A 470
 None
 1.17A 6fhwB-3ubrA:
undetectable		 6fhwB-3ubrA:
10.26