SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uc0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3uc0 ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 160
GLY A 159
LEU A 181
 None
None
None
GOL  A 337 ( 3.8A)
None
 1.35A 1lwcA-3uc0A:
undetectable		 1lwcA-3uc0A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3uc0 ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 160
TYR A 178
GLY A 159
 None
None
None
GOL  A 337 ( 4.8A)
GOL  A 337 ( 3.8A)
 1.39A 1lwcA-3uc0A:
undetectable		 1lwcA-3uc0A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3uc0 ENVELOPE PROTEIN
(Dengue
virus) 		5 / 9 LEU A  25
VAL A  31
THR A  33
VAL A  21
ASP A  22
 None
 1.38A 2l8mA-3uc0A:
undetectable		 2l8mA-3uc0A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3uc0 ENVELOPE PROTEIN
(Dengue
virus) 		3 / 3 PRO A 166
GLY A 134
TYR A 137
 None
 0.69A 2vouA-3uc0A:
undetectable		 2vouA-3uc0A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HTH_B_PRLB201_0
(EBRA REPRESSOR)		 3uc0 ENVELOPE PROTEIN
HEAVY CHAIN,
MONOCLONAL ANTIBODY
5H2
(Dengue
virus;
Pan
troglodytes) 		5 / 9 VAL A 139
LEU A 181
TYR H  33
TYR H  50
LEU A 175
 None
 1.37A 3hthB-3uc0A:
undetectable		 3hthB-3uc0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3uc0 ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 160
GLY A 159
LEU A 181
 None
None
None
GOL  A 337 ( 3.8A)
None
 1.34A 5hbmA-3uc0A:
undetectable		 5hbmA-3uc0A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3uc0 ENVELOPE PROTEIN
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 160
TYR A 178
GLY A 159
 None
None
None
GOL  A 337 ( 4.8A)
GOL  A 337 ( 3.8A)
 1.36A 5hbmA-3uc0A:
undetectable		 5hbmA-3uc0A:
15.58