SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 1.01A 1fbyA-3uc2A:
undetectable		 1fbyA-3uc2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 1.01A 1fbyB-3uc2A:
undetectable		 1fbyB-3uc2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 0.97A 1fm6A-3uc2A:
undetectable		 1fm6A-3uc2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 1.03A 1xdkA-3uc2A:
undetectable		 1xdkA-3uc2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 1.03A 1xdkE-3uc2A:
undetectable		 1xdkE-3uc2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 0.96A 1xiuA-3uc2A:
undetectable		 1xiuA-3uc2A:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 10 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 0.95A 3falC-3uc2A:
undetectable		 3falC-3uc2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 11 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 0.97A 3fc6A-3uc2A:
undetectable		 3fc6A-3uc2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		4 / 8 LYS A  84
ASP A  80
LEU A 113
SER A  77
 None
 0.94A 3lm8A-3uc2A:
undetectable
3lm8C-3uc2A:
undetectable		 3lm8A-3uc2A:
20.81
3lm8C-3uc2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 11 PRO A  63
ASN A 101
LEU A 102
VAL A  48
ALA A  47
 None
 1.35A 3n23C-3uc2A:
undetectable		 3n23C-3uc2A:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 110
GLU A 111
THR A 112
 None
 0.76A 3v4tA-3uc2A:
undetectable		 3v4tA-3uc2A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 0.93A 5uanA-3uc2A:
undetectable		 5uanA-3uc2A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3uc2 HYPOTHETICAL PROTEIN
WITH
IMMUNOGLOBULIN-LIKE
FOLD
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  59
ALA A 103
GLN A 104
PHE A 105
LEU A  88
 None
 0.99A 6a5yD-3uc2A:
undetectable		 6a5yD-3uc2A:
24.47