SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 116
LEU A 101
VAL A  68
ALA A 108
ALA A 107
 None
 1.14A 1n5xA-3uc9A:
undetectable		 1n5xA-3uc9A:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 116
LEU A 101
VAL A  68
ALA A 108
ALA A 107
 None
 1.14A 1n5xB-3uc9A:
undetectable		 1n5xB-3uc9A:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ABZ_A_T1CA1209_1
(TETRACYCLINE
REPRESSOR CLASS D)		 3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 176
ASN A 111
PHE A 113
GLN A   7
LEU A  79
 None
 1.50A 4abzA-3uc9A:
0.0		 4abzA-3uc9A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 176
ASN A 111
PHE A 113
GLN A   7
LEU A  79
 None
 1.49A 4ac0A-3uc9A:
undetectable		 4ac0A-3uc9A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6
(Saccharomyces
cerevisiae) 		3 / 3 TRP A  45
GLN A 184
THR A  44
 None
 0.92A 4m2xA-3uc9A:
undetectable		 4m2xA-3uc9A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 166
LEU A  21
HIS A  18
ILE A  92
 None
 1.02A 4ok1A-3uc9A:
undetectable		 4ok1A-3uc9A:
18.94