SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ucg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3ucg POLYADENYLATE-BINDIN
G PROTEIN 2
(Homo
sapiens) 		4 / 7 ALA A 183
ASP A 180
GLY A 182
PHE A 237
 None
 0.74A 2c49B-3ucgA:
undetectable		 2c49B-3ucgA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ucg POLYADENYLATE-BINDIN
G PROTEIN 2
(Homo
sapiens) 		4 / 7 VAL A 201
PHE A 192
HIS A 191
GLU A 187
 None
 1.08A 5ad9A-3ucgA:
undetectable
5ad9B-3ucgA:
undetectable		 5ad9A-3ucgA:
11.85
5ad9B-3ucgA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 3ucg POLYADENYLATE-BINDIN
G PROTEIN 2
(Homo
sapiens) 		3 / 3 ARG A 240
ARG A 238
ASP A 180
 EDO  A 301 ( 3.6A)
None
None
 0.94A 6d8pA-3ucgA:
2.4		 6d8pA-3ucgA:
8.46