SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ucq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		6 / 12 TYR A 140
ASP A 284
ALA A 285
HIS A 395
ASP A 396
ARG A 524
 GOL  A 720 (-4.0A)
GOL  A 720 (-3.0A)
None
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
None
 0.63A 1dedA-3ucqA:
23.6		 1dedA-3ucqA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		6 / 12 TYR A 140
ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
 GOL  A 720 (-4.0A)
GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
 0.86A 1dedB-3ucqA:
27.8		 1dedB-3ucqA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 TYR A 140
ARG A 282
ASP A 284
ALA A 285
HIS A 395
ASP A 396
ARG A 524
 GOL  A 720 (-4.0A)
GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
None
 0.66A 1dedB-3ucqA:
27.8		 1dedB-3ucqA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 MET A 155
LEU A 158
SER A 159
 None
 0.69A 1ee2A-3ucqA:
0.7		 1ee2A-3ucqA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 GLY A 427
GLN A 428
ALA A 365
LEU A 364
PHE A 433
 None
 1.12A 1gs4A-3ucqA:
undetectable		 1gs4A-3ucqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 THR A 386
SER A 385
TYR A 352
LEU A 494
 None
None
GOL  A 721 (-3.6A)
None
 1.12A 1ibgL-3ucqA:
undetectable		 1ibgL-3ucqA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 6 ARG A 520
GLY A 138
ASP A 137
TYR A  97
 GOL  A 720 ( 3.1A)
GOL  A 710 (-3.7A)
GOL  A 720 (-2.6A)
GOL  A 710 (-4.4A)
 1.22A 1kf6M-3ucqA:
undetectable
1kf6N-3ucqA:
undetectable		 1kf6M-3ucqA:
24.01
1kf6N-3ucqA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 HIS A 180
ALA A 285
GLU A 326
ILE A 328
ASP A 396
 GOL  A 720 (-3.8A)
None
TRS  A 700 (-4.2A)
None
TRS  A 700 (-3.1A)
 0.64A 1kxhA-3ucqA:
18.4		 1kxhA-3ucqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		8 / 12 TYR A 140
HIS A 180
PHE A 248
ARG A 282
ASP A 284
GLU A 326
HIS A 395
ASP A 396
 GOL  A 720 (-4.0A)
GOL  A 720 (-3.8A)
GOL  A 720 (-4.2A)
GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
 1.04A 1mxdA-3ucqA:
24.0		 1mxdA-3ucqA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 LEU A 628
LEU A 604
ALA A 579
VAL A 633
LEU A 641
 None
 0.93A 1rbpA-3ucqA:
undetectable		 1rbpA-3ucqA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 PRO A  69
ILE A 270
GLY A 277
VAL A 280
ALA A 320
 None
 1.13A 1sg9C-3ucqA:
4.4		 1sg9C-3ucqA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 GLY A 194
ASP A 233
ASP A 195
ALA A 191
ALA A 188
 None
GOL  A 716 (-3.6A)
None
None
None
 1.09A 2br4F-3ucqA:
undetectable		 2br4F-3ucqA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 GLY A 237
PHE A 205
GLY A 242
GLY A 241
PHE A 214
 None
None
None
None
GOL  A 719 (-4.4A)
 0.98A 2dpmA-3ucqA:
undetectable		 2dpmA-3ucqA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 ARG A 149
GLU A 133
ALA A 141
ALA A 182
 GOL  A 710 (-3.0A)
None
None
None
 1.01A 2ejfA-3ucqA:
undetectable		 2ejfA-3ucqA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.71A 3aicA-3ucqA:
2.2		 3aicA-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.70A 3aicB-3ucqA:
4.7		 3aicB-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		8 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
TYR A 140
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
GOL  A 720 (-4.0A)
 0.67A 3aicC-3ucqA:
6.0		 3aicC-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.73A 3aicD-3ucqA:
6.0		 3aicD-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.72A 3aicE-3ucqA:
6.0		 3aicE-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.70A 3aicF-3ucqA:
5.8		 3aicF-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.67A 3aicG-3ucqA:
5.5		 3aicG-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		6 / 12 ARG A 282
ASP A 284
GLU A 326
HIS A 395
ASP A 396
GLN A 252
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 ( 4.4A)
 1.07A 3aicG-3ucqA:
5.5		 3aicG-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		7 / 12 ARG A 282
ASP A 284
ALA A 285
GLU A 326
HIS A 395
ASP A 396
ASP A 137
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
None
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
 0.74A 3aicH-3ucqA:
6.1		 3aicH-3ucqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 4 LEU A 504
ARG A 478
LEU A 479
ALA A 463
 None
 0.88A 3b9mA-3ucqA:
3.0		 3b9mA-3ucqA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 6 SER A 422
TYR A 425
LEU A 421
LEU A 457
 None
 1.02A 3f33A-3ucqA:
undetectable		 3f33A-3ucqA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 4 LEU A 531
ALA A 502
VAL A 546
PRO A 542
 None
 1.21A 3gv1B-3ucqA:
undetectable		 3gv1B-3ucqA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 GLN A  13
VAL A  60
LEU A 264
PHE A  27
ALA A 313
 None
 1.14A 3kk6A-3ucqA:
undetectable		 3kk6A-3ucqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 ALA A 285
ARG A 282
LYS A 324
 None
GOL  A 721 (-3.4A)
None
 1.06A 3kp5B-3ucqA:
undetectable		 3kp5B-3ucqA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 ARG A 393
ASP A 518
GLN A 252
 None
GOL  A 711 ( 3.7A)
GOL  A 720 ( 4.4A)
 0.91A 3lcvB-3ucqA:
undetectable		 3lcvB-3ucqA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 HIS A 395
ASP A 396
ASP A 137
LEU A 178
GLU A 326
 GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
GOL  A 720 (-2.6A)
None
TRS  A 700 (-4.2A)
 1.43A 3lmyA-3ucqA:
11.2		 3lmyA-3ucqA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 VAL A 492
VAL A 173
SER A 171
 None
 0.70A 3n8xB-3ucqA:
undetectable		 3n8xB-3ucqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 6 GLU A 110
TRP A 529
ARG A 111
GLY A 107
 None
 1.30A 3oxvA-3ucqA:
undetectable		 3oxvA-3ucqA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 LEU A 112
ALA A  96
VAL A 120
LEU A 165
GLY A 498
 None
 0.77A 4dc3A-3ucqA:
undetectable		 4dc3A-3ucqA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 6 LEU A 310
ILE A 316
MET A  61
TRP A  39
 None
 1.00A 4do3B-3ucqA:
undetectable		 4do3B-3ucqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 TYR A 638
ARG A 367
SER A 598
 None
 0.84A 4dr2I-3ucqA:
undetectable
4dr2J-3ucqA:
1.0		 4dr2I-3ucqA:
12.30
4dr2J-3ucqA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 5 ARG A 393
ILE A 450
TRP A 400
GLY A 399
 None
 1.39A 4e7cC-3ucqA:
undetectable		 4e7cC-3ucqA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 5 TYR A  46
LEU A  42
LEU A 264
ARG A  56
 None
 1.22A 4em2A-3ucqA:
0.8		 4em2A-3ucqA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 TYR A 638
ARG A 367
SER A 598
 None
 0.82A 4lf7I-3ucqA:
undetectable
4lf7J-3ucqA:
undetectable		 4lf7I-3ucqA:
12.30
4lf7J-3ucqA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 TYR A 638
ARG A 367
SER A 598
 None
 0.82A 4lf8I-3ucqA:
undetectable
4lf8J-3ucqA:
undetectable		 4lf8I-3ucqA:
12.30
4lf8J-3ucqA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 9 ALA A 458
ALA A 454
SER A 453
ALA A 502
ALA A 475
 None
 1.30A 4twdA-3ucqA:
undetectable
4twdB-3ucqA:
undetectable
4twdC-3ucqA:
undetectable
4twdD-3ucqA:
undetectable
4twdE-3ucqA:
undetectable		 4twdA-3ucqA:
19.17
4twdB-3ucqA:
19.17
4twdC-3ucqA:
19.17
4twdD-3ucqA:
19.17
4twdE-3ucqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 THR A 387
GLY A 490
ARG A 557
ALA A 565
 None
 0.90A 4txnA-3ucqA:
undetectable		 4txnA-3ucqA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 THR A 387
GLY A 490
ARG A 557
ALA A 565
 None
 0.91A 4txnB-3ucqA:
undetectable		 4txnB-3ucqA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 THR A 387
GLY A 490
ARG A 557
ALA A 565
 None
 0.96A 4txnC-3ucqA:
undetectable		 4txnC-3ucqA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 THR A 387
GLY A 490
ARG A 557
ALA A 565
 None
 0.92A 4txnD-3ucqA:
undetectable		 4txnD-3ucqA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		6 / 9 LEU A 635
ALA A 579
LEU A 604
LEU A 609
LEU A 643
LEU A 641
 None
 1.25A 4z91F-3ucqA:
0.4
4z91G-3ucqA:
undetectable
4z91H-3ucqA:
undetectable
4z91I-3ucqA:
undetectable
4z91J-3ucqA:
undetectable		 4z91F-3ucqA:
18.65
4z91G-3ucqA:
18.65
4z91H-3ucqA:
18.65
4z91I-3ucqA:
18.65
4z91J-3ucqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 GLY A 389
GLY A 491
GLY A 490
ALA A 325
LEU A 334
 None
 0.93A 5c0oF-3ucqA:
undetectable		 5c0oF-3ucqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 ARG A 282
ASP A 284
GLU A 326
HIS A 395
ASP A 396
 GOL  A 721 (-3.4A)
GOL  A 720 (-3.0A)
TRS  A 700 (-4.2A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
 0.29A 5csyB-3ucqA:
18.4		 5csyB-3ucqA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 PRO A 227
ILE A 221
GLN A 440
PHE A 248
ASN A 249
 None
TRS  A 700 (-4.4A)
GOL  A 712 ( 3.6A)
GOL  A 720 (-4.2A)
GOL  A 711 (-3.6A)
 1.03A 5hgcA-3ucqA:
undetectable		 5hgcA-3ucqA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 LEU A 174
THR A 104
ASP A 151
LEU A 273
 None
 0.74A 5jq7B-3ucqA:
undetectable		 5jq7B-3ucqA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 ASP A 175
ARG A 282
ASP A 137
 None
GOL  A 721 (-3.4A)
GOL  A 720 (-2.6A)
 0.85A 5zvgA-3ucqA:
undetectable		 5zvgA-3ucqA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		3 / 3 ASP A 175
ARG A 282
ASP A 137
 None
GOL  A 721 (-3.4A)
GOL  A 720 (-2.6A)
 0.89A 5zvgB-3ucqA:
undetectable		 5zvgB-3ucqA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 TYR A 140
HIS A 180
ASP A 284
HIS A 395
ASP A 396
 GOL  A 720 (-4.0A)
GOL  A 720 (-3.8A)
GOL  A 720 (-3.0A)
GOL  A 721 (-4.6A)
TRS  A 700 (-3.1A)
 0.51A 6ag0A-3ucqA:
20.6		 6ag0A-3ucqA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 ASP A 284
HIS A 124
LEU A 123
ARG A 100
GLY A 139
 GOL  A 720 (-3.0A)
None
None
GOL  A 710 (-4.0A)
GOL  A 710 ( 4.1A)
 1.03A 6b0lB-3ucqA:
undetectable		 6b0lB-3ucqA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 6 LEU A 334
ASP A 284
GLN A 252
GLU A 326
 None
GOL  A 720 (-3.0A)
GOL  A 720 ( 4.4A)
TRS  A 700 (-4.2A)
 1.34A 6djzC-3ucqA:
3.0		 6djzC-3ucqA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		5 / 12 ALA A 532
TYR A 114
TRP A 529
GLY A 103
TYR A  94
 GOL  A 715 ( 4.0A)
GOL  A 715 (-4.6A)
None
None
None
 1.47A 6fhwB-3ucqA:
undetectable		 6fhwB-3ucqA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 ASP A 518
ARG A 524
GLN A 252
TYR A 140
 GOL  A 711 ( 3.7A)
None
GOL  A 720 ( 4.4A)
GOL  A 720 (-4.0A)
 1.38A 6g31G-3ucqA:
undetectable		 6g31G-3ucqA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 7 ILE A 170
LEU A 112
LEU A 161
LEU A 172
 None
 0.69A 6g9bA-3ucqA:
undetectable
6g9bB-3ucqA:
0.5		 6g9bA-3ucqA:
7.50
6g9bB-3ucqA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3ucq AMYLOSUCRASE
(Deinococcus
geothermalis) 		4 / 5 LEU A 582
TYR A 595
ILE A 398
GLY A 488
 None
 0.91A 6hd6A-3ucqA:
undetectable		 6hd6A-3ucqA:
8.94