SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ucx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ASP A  64
ILE A  65
THR A  66
LEU A 115
 None
 0.73A 1hmyA-3ucxA:
6.4		 1hmyA-3ucxA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 ARG A 224
ALA A 218
SER A 220
TYR A 213
 None
None
None
1PE  A 262 ( 3.9A)
 1.11A 1j36A-3ucxA:
0.0		 1j36A-3ucxA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 ARG A 224
ALA A 218
SER A 220
TYR A 213
 None
None
None
1PE  A 262 ( 3.9A)
 1.11A 1j36B-3ucxA:
0.5		 1j36B-3ucxA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  59
ALA A  37
HIS A  73
ASP A  76
 None
 1.34A 2dpzA-3ucxA:
undetectable		 2dpzA-3ucxA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  16
PRO A  17
ILE A  65
THR A  66
LEU A 115
 CL  A 261 (-3.2A)
CL  A 261 ( 4.7A)
None
None
None
 1.06A 4n48A-3ucxA:
6.9		 4n48A-3ucxA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  16
PRO A  17
ILE A  65
THR A  66
LEU A 115
 CL  A 261 (-3.2A)
CL  A 261 ( 4.7A)
None
None
None
 1.01A 4n49A-3ucxA:
7.3		 4n49A-3ucxA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ucx SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  20
VAL A  51
THR A  52
ALA A  37
LEU A  36
 CL  A 261 (-3.8A)
None
None
None
None
 1.04A 5kocA-3ucxA:
5.4		 5kocA-3ucxA:
20.40