SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ud2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 5 GLU C 968
ARG C1210
LEU C1069
ASP C1003
 None
 0.88A 1n13B-3ud2C:
undetectable
1n13C-3ud2C:
undetectable		 1n13B-3ud2C:
13.19
1n13C-3ud2C:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 6 GLU C 968
ARG C1210
LEU C1069
ASP C1003
 None
 0.95A 1n13H-3ud2C:
undetectable
1n13K-3ud2C:
undetectable		 1n13H-3ud2C:
13.19
1n13K-3ud2C:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 7 LEU C1069
ASP C1003
GLU C 968
ARG C1210
 None
 0.90A 1n13G-3ud2C:
undetectable
1n13J-3ud2C:
undetectable		 1n13G-3ud2C:
9.82
1n13J-3ud2C:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 7 LEU C1069
ASP C1003
GLU C 968
ARG C1210
 None
 0.91A 1n13I-3ud2C:
undetectable
1n13L-3ud2C:
undetectable		 1n13I-3ud2C:
9.82
1n13L-3ud2C:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		3 / 3 PHE C1203
ARG C1143
ASN C1206
 None
 0.95A 1xzxX-3ud2C:
undetectable		 1xzxX-3ud2C:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 5 ILE C 993
SER C 929
ARG C 927
LEU C 934
 None
 1.04A 1y0xX-3ud2C:
undetectable		 1y0xX-3ud2C:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		5 / 12 ILE C1188
THR C1192
LEU C1172
CYH C1174
VAL C1176
 None
 1.20A 2qo5A-3ud2C:
undetectable		 2qo5A-3ud2C:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		5 / 12 ALA C 945
PRO C 946
THR C1057
ILE C 938
PHE C 985
 None
 1.30A 2v95A-3ud2C:
undetectable		 2v95A-3ud2C:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 5 THR C1191
ILE C1188
GLU C1186
PHE C1211
 None
 1.38A 4ac9C-3ud2C:
undetectable		 4ac9C-3ud2C:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 5 THR C1191
ILE C1188
GLU C1186
PHE C1211
 None
 1.37A 4acbC-3ud2C:
undetectable		 4acbC-3ud2C:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3ud2 ANKYRIN-1
(Homo
sapiens) 		5 / 12 ALA C1107
GLN C1111
ILE C1131
GLY C1179
ASP C1181
 None
 1.27A 4iilA-3ud2C:
undetectable		 4iilA-3ud2C:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 7 LEU C1121
VAL C1118
PRO C1114
GLU C1232
 None
 1.05A 4lb2A-3ud2C:
undetectable		 4lb2A-3ud2C:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		5 / 12 THR C1219
ALA C1222
LEU C1173
LEU C1213
GLY C1190
 None
 1.08A 4xi3C-3ud2C:
undetectable		 4xi3C-3ud2C:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 8 ILE C 949
CYH C 951
ARG C 952
LEU C1061
 None
 0.82A 4xtaB-3ud2C:
undetectable		 4xtaB-3ud2C:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		4 / 6 ARG C1010
PHE C1063
ILE C1055
THR C1056
 None
 1.14A 5vceA-3ud2C:
undetectable		 5vceA-3ud2C:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3ud2 ANKYRIN-1
(Homo
sapiens) 		3 / 3 ALA C1220
PHE C1225
GLN C1125
 None
 0.77A 6eceA-3ud2C:
undetectable		 6eceA-3ud2C:
23.45