SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3udu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 6 PRO A 109
PHE A 307
LEU A 303
SER A 306
 None
 1.17A 1sbrA-3uduA:
undetectable
1sbrB-3uduA:
undetectable		 1sbrA-3uduA:
18.46
1sbrB-3uduA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		3 / 3 ASP A  68
PHE A 101
ASN A  40
 None
 0.84A 1sg9B-3uduA:
2.1		 1sg9B-3uduA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 LEU A 324
SER A 321
ILE A 293
LEU A 260
ASP A 132
 None
 1.24A 3ko0A-3uduA:
0.6
3ko0B-3uduA:
0.6
3ko0C-3uduA:
undetectable
3ko0D-3uduA:
undetectable		 3ko0A-3uduA:
16.22
3ko0B-3uduA:
16.22
3ko0C-3uduA:
16.22
3ko0D-3uduA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ASP A 132
LEU A 324
SER A 321
ILE A 293
LEU A 260
 None
 1.25A 3ko0G-3uduA:
undetectable
3ko0H-3uduA:
0.6
3ko0I-3uduA:
0.6
3ko0J-3uduA:
0.6		 3ko0G-3uduA:
16.22
3ko0H-3uduA:
16.22
3ko0I-3uduA:
16.22
3ko0J-3uduA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 11 ASP A 132
LEU A 260
LEU A 324
SER A 321
ILE A 293
 None
 1.22A 3ko0A-3uduA:
0.6
3ko0B-3uduA:
0.6
3ko0I-3uduA:
0.7
3ko0J-3uduA:
0.6		 3ko0A-3uduA:
16.22
3ko0B-3uduA:
16.22
3ko0I-3uduA:
16.22
3ko0J-3uduA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 LEU A 324
SER A 321
ILE A 293
LEU A 260
ASP A 132
 None
 1.19A 3ko0K-3uduA:
undetectable
3ko0L-3uduA:
undetectable
3ko0S-3uduA:
undetectable
3ko0T-3uduA:
0.6		 3ko0K-3uduA:
16.22
3ko0L-3uduA:
16.22
3ko0S-3uduA:
16.22
3ko0T-3uduA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 LEU A 324
SER A 321
ILE A 293
LEU A 260
ASP A 132
 None
 1.22A 3ko0M-3uduA:
undetectable
3ko0N-3uduA:
undetectable
3ko0O-3uduA:
undetectable
3ko0P-3uduA:
undetectable		 3ko0M-3uduA:
16.22
3ko0N-3uduA:
16.22
3ko0O-3uduA:
16.22
3ko0P-3uduA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ASP A 132
LEU A 260
LEU A 324
SER A 321
ILE A 293
 None
 1.21A 3ko0M-3uduA:
undetectable
3ko0N-3uduA:
undetectable
3ko0O-3uduA:
undetectable
3ko0P-3uduA:
undetectable		 3ko0M-3uduA:
16.22
3ko0N-3uduA:
16.22
3ko0O-3uduA:
16.22
3ko0P-3uduA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 ALA A 299
MET A  19
LEU A  39
LYS A   5
ILE A  70
 None
 1.14A 3ql3A-3uduA:
undetectable		 3ql3A-3uduA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 PRO A 276
GLY A 278
GLY A 279
LEU A 107
LEU A 139
 None
 0.99A 4fp9A-3uduA:
undetectable		 4fp9A-3uduA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 PRO A 276
GLY A 278
GLY A 279
LEU A 107
LEU A 139
 None
 0.99A 4fp9C-3uduA:
undetectable		 4fp9C-3uduA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 PRO A 276
GLY A 278
GLY A 279
LEU A 107
LEU A 139
 None
 0.99A 4fp9D-3uduA:
undetectable		 4fp9D-3uduA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 PRO A 276
GLY A 278
GLY A 279
LEU A 107
LEU A 139
 None
 0.99A 4fp9F-3uduA:
undetectable		 4fp9F-3uduA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 12 PRO A 276
GLY A 278
GLY A 279
LEU A 107
LEU A 139
 None
 0.99A 4fzvA-3uduA:
undetectable		 4fzvA-3uduA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 8 ASP A 315
ASN A 318
ALA A 319
GLU A 354
 None
 0.90A 4zbqA-3uduA:
undetectable		 4zbqA-3uduA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		5 / 10 ALA A  42
LEU A   9
ALA A  10
SER A  93
LEU A  56
 None
 1.17A 4zbrA-3uduA:
undetectable		 4zbrA-3uduA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 5 TYR A 144
ILE A 143
LEU A 247
GLY A 244
 None
 0.93A 5kmdC-3uduA:
undetectable
5kmdD-3uduA:
undetectable		 5kmdC-3uduA:
22.99
5kmdD-3uduA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3udu 3-ISOPROPYLMALATE
DEHYDROGENASE
(Campylobacter
jejuni) 		4 / 7 ASP A 315
ASN A 318
ALA A 319
GLU A 354
 None
 0.77A 6ci6A-3uduA:
undetectable		 6ci6A-3uduA:
14.50