SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ue6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		5 / 11 ASN A 312
SER A 207
LEU A 208
ALA A 211
LEU A 212
 None
 1.17A 1hwkB-3ue6A:
undetectable		 1hwkB-3ue6A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		5 / 11 ASN A 312
SER A 207
LEU A 208
ALA A 211
LEU A 212
 None
 1.18A 1hwkA-3ue6A:
undetectable		 1hwkA-3ue6A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		5 / 11 ASN A 312
SER A 207
LEU A 208
ALA A 211
LEU A 212
 None
 1.16A 1hwkD-3ue6A:
undetectable		 1hwkD-3ue6A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		5 / 11 ASN A 312
SER A 207
LEU A 208
ALA A 211
LEU A 212
 None
 1.16A 1hwkC-3ue6A:
undetectable		 1hwkC-3ue6A:
16.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		8 / 12 VAL A 220
ASN A 229
ASN A 253
ARG A 255
GLN A 258
ASN A 286
ASN A 296
GLN A 317
 None
FMN  A 500 (-3.9A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.43A 4kukA-3ue6A:
19.3		 4kukA-3ue6A:
35.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		7 / 12 VAL A 220
ASN A 253
CYH A 254
ARG A 255
GLN A 258
ASN A 296
GLN A 317
 None
FMN  A 500 (-3.1A)
FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.72A 4kukA-3ue6A:
19.3		 4kukA-3ue6A:
35.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		8 / 12 VAL A 220
ASN A 229
ASN A 253
ARG A 255
GLN A 258
ASN A 286
ASN A 296
GLN A 317
 None
FMN  A 500 (-3.9A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.57A 4kuoA-3ue6A:
19.5		 4kuoA-3ue6A:
35.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		8 / 12 VAL A 220
ASN A 229
ASN A 253
CYH A 254
ARG A 255
GLN A 258
ASN A 296
GLN A 317
 None
FMN  A 500 (-3.9A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.80A 4kuoA-3ue6A:
19.5		 4kuoA-3ue6A:
35.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		7 / 12 ARG A 255
GLN A 258
ILE A 274
ASN A 286
ASN A 296
GLY A 315
GLN A 317
 FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.79A 4r38A-3ue6A:
18.9		 4r38A-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		6 / 12 CYH A 254
ARG A 255
GLN A 258
ILE A 274
GLY A 315
GLN A 317
 FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.94A 4r38A-3ue6A:
18.9		 4r38A-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		8 / 12 ASN A 253
ARG A 255
GLN A 258
ILE A 274
ASN A 286
ASN A 296
GLY A 315
GLN A 317
 FMN  A 500 (-3.1A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.76A 4r38B-3ue6A:
19.0		 4r38B-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		7 / 12 ASN A 253
CYH A 254
ARG A 255
GLN A 258
ILE A 274
GLY A 315
GLN A 317
 FMN  A 500 (-3.1A)
FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.92A 4r38B-3ue6A:
19.0		 4r38B-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		7 / 12 ARG A 255
GLN A 258
ILE A 274
ASN A 286
ASN A 296
GLY A 315
GLN A 317
 FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.78A 4r38C-3ue6A:
18.9		 4r38C-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		6 / 12 CYH A 254
ARG A 255
GLN A 258
ILE A 274
GLY A 315
GLN A 317
 FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.93A 4r38C-3ue6A:
18.9		 4r38C-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		7 / 12 ARG A 255
GLN A 258
ILE A 274
ASN A 286
ASN A 296
GLY A 315
GLN A 317
 FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.77A 4r38D-3ue6A:
18.9		 4r38D-3ue6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		6 / 12 CYH A 254
ARG A 255
GLN A 258
ILE A 274
GLY A 315
GLN A 317
 FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.95A 4r38D-3ue6A:
18.9		 4r38D-3ue6A:
34.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		7 / 12 CYH A 254
ARG A 255
GLN A 258
ILE A 274
ASN A 286
ASN A 296
GLN A 317
 FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.82A 4r3aA-3ue6A:
15.1		 4r3aA-3ue6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		6 / 12 ARG A 255
ILE A 274
ASN A 286
ASN A 296
GLY A 315
GLN A 317
 FMN  A 500 (-3.6A)
FMN  A 500 (-4.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.57A 4r3aB-3ue6A:
15.1		 4r3aB-3ue6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		6 / 12 CYH A 254
ARG A 255
ILE A 274
ASN A 296
GLY A 315
GLN A 317
 FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-4.9A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
 0.85A 4r3aB-3ue6A:
15.1		 4r3aB-3ue6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		4 / 6 SER A 245
LEU A 246
ASP A 247
LEU A 239
 None
 0.73A 4wozA-3ue6A:
undetectable
4wozB-3ue6A:
undetectable		 4wozA-3ue6A:
20.13
4wozB-3ue6A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3ue6 AUREOCHROME1
(Vaucheria
frigida) 		4 / 6 ARG A 304
ALA A 224
THR A 222
ALA A 301
 None
None
FMN  A 500 (-3.4A)
None
 1.13A 6ma6A-3ue6A:
undetectable		 6ma6A-3ue6A:
18.90