SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ue9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 7 PHE A  43
ILE A 143
TYR A 147
GLY A  81
 None
 0.94A 11gsA-3ue9A:
undetectable		 11gsA-3ue9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 ARG A 104
LEU A  89
LEU A  84
VAL A 158
ALA A 212
 None
 1.24A 1gseA-3ue9A:
undetectable		 1gseA-3ue9A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 ASP A 294
LEU A 375
ASP A 329
THR A 244
GLY A 284
 None
 1.13A 1ia0B-3ue9A:
undetectable		 1ia0B-3ue9A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 11 ASN A 340
GLY A 274
THR A 276
GLY A  22
GLN A  20
 None
 1.34A 1jr1A-3ue9A:
undetectable		 1jr1A-3ue9A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 6 GLY A 341
ILE A 339
VAL A  17
SER A 336
 None
 1.10A 1rs7B-3ue9A:
undetectable		 1rs7B-3ue9A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 LEU A 117
HIS A 178
ILE A 123
 None
 0.59A 1s9pB-3ue9A:
undetectable		 1s9pB-3ue9A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 ASP A 294
LEU A 375
ASP A 329
THR A 244
GLY A 284
 None
 1.13A 1tubB-3ue9A:
undetectable		 1tubB-3ue9A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 LEU A  33
GLU A 231
GLY A 232
ASP A 239
ALA A 257
 None
 1.33A 2bm9B-3ue9A:
undetectable		 2bm9B-3ue9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 11 PHE A  43
VAL A  15
ILE A 272
LEU A 269
ILE A 339
 None
 1.10A 2dg9A-3ue9A:
undetectable		 2dg9A-3ue9A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 6 ARG A  42
GLY A 232
PHE A  43
THR A 236
 None
 1.01A 2m2oB-3ue9A:
undetectable		 2m2oB-3ue9A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 323
GLU A 314
SER A 336
 None
 0.81A 2xctD-3ue9A:
undetectable		 2xctD-3ue9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 8 SER A 336
ILE A 275
ASN A 340
VAL A 342
 None
 0.72A 3dcjB-3ue9A:
undetectable		 3dcjB-3ue9A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 11 ALA A 255
GLY A 274
LEU A 269
VAL A  14
ARG A  12
 None
 0.86A 3dcmX-3ue9A:
2.4		 3dcmX-3ue9A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  79
GLY A  81
GLY A  45
ASP A 213
VAL A 214
 None
 1.05A 3gczA-3ue9A:
undetectable		 3gczA-3ue9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  18
VAL A 422
SER A 336
ALA A 332
ALA A 331
 None
 0.95A 3keeB-3ue9A:
undetectable		 3keeB-3ue9A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  18
VAL A 422
SER A 336
ALA A 332
ALA A 331
 None
 0.96A 3keeC-3ue9A:
undetectable		 3keeC-3ue9A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 LEU A  62
ILE A  69
GLU A  92
LEU A  96
SER A  85
 None
 1.12A 3ko0A-3ue9A:
undetectable
3ko0B-3ue9A:
undetectable
3ko0C-3ue9A:
undetectable
3ko0D-3ue9A:
undetectable		 3ko0A-3ue9A:
13.17
3ko0B-3ue9A:
13.17
3ko0C-3ue9A:
13.17
3ko0D-3ue9A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 SER A  85
LEU A  62
ILE A  69
GLU A  92
LEU A  96
 None
 1.11A 3ko0G-3ue9A:
undetectable
3ko0H-3ue9A:
undetectable
3ko0I-3ue9A:
undetectable
3ko0J-3ue9A:
undetectable		 3ko0G-3ue9A:
13.17
3ko0H-3ue9A:
13.17
3ko0I-3ue9A:
13.17
3ko0J-3ue9A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 LEU A  62
ILE A  69
GLU A  92
LEU A  96
SER A  85
 None
 0.93A 3ko0K-3ue9A:
undetectable
3ko0L-3ue9A:
undetectable
3ko0S-3ue9A:
undetectable
3ko0T-3ue9A:
undetectable		 3ko0K-3ue9A:
13.17
3ko0L-3ue9A:
13.17
3ko0S-3ue9A:
13.17
3ko0T-3ue9A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 4 ASP A 296
ASP A 294
GLY A 284
THR A 281
 None
 1.06A 3tl9B-3ue9A:
undetectable		 3tl9B-3ue9A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 5 ASP A  31
SER A  67
GLY A  68
ASP A  35
 None
 1.24A 3w9tB-3ue9A:
undetectable		 3w9tB-3ue9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 5 ASP A  31
SER A  67
GLY A  68
ASP A  35
 None
 1.24A 3w9tC-3ue9A:
undetectable		 3w9tC-3ue9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 5 ASP A  31
SER A  67
GLY A  68
ASP A  35
 None
 1.25A 3w9tD-3ue9A:
undetectable		 3w9tD-3ue9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 5 GLY A 341
ILE A 339
VAL A  17
SER A 336
 None
 1.21A 4d33A-3ue9A:
undetectable		 4d33A-3ue9A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 6 GLY A 341
ILE A 339
VAL A  17
SER A 336
 None
 1.03A 4kcnA-3ue9A:
undetectable		 4kcnA-3ue9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 LEU A 117
PRO A 118
ARG A 172
 None
 0.75A 4klrB-3ue9A:
undetectable		 4klrB-3ue9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 7 VAL A  40
ALA A  37
PHE A 446
TYR A 271
 None
 1.00A 4lb2A-3ue9A:
undetectable		 4lb2A-3ue9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 5 PHE A  43
PHE A 230
LEU A  33
PRO A 445
 None
 1.42A 4o8zA-3ue9A:
undetectable		 4o8zA-3ue9A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 6 ILE A 143
GLN A 234
ILE A 240
ASP A 239
 None
 1.22A 4z4dA-3ue9A:
undetectable		 4z4dA-3ue9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 LEU A 333
ALA A 332
LEU A 361
MET A 347
LEU A 237
 None
 1.20A 4zn7A-3ue9A:
undetectable		 4zn7A-3ue9A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  79
GLY A  81
GLY A  45
ASP A 213
VAL A 214
 None
 1.04A 5ehiC-3ue9A:
undetectable		 5ehiC-3ue9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 8 TYR A 415
THR A 348
TYR A 279
TRP A 395
 None
 1.49A 5kxiD-3ue9A:
undetectable
5kxiE-3ue9A:
undetectable		 5kxiD-3ue9A:
21.43
5kxiE-3ue9A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		5 / 12 GLY A  81
ILE A 109
VAL A 158
ILE A 116
ILE A  78
 None
 0.88A 5t8hB-3ue9A:
undetectable		 5t8hB-3ue9A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 226
ARG A 217
ARG A 106
 None
 0.88A 5vcgA-3ue9A:
undetectable		 5vcgA-3ue9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 5 LEU A 353
LYS A 349
LEU A 308
GLU A 314
 None
 1.22A 5weaA-3ue9A:
1.7		 5weaA-3ue9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		4 / 6 ILE A 143
GLN A 234
ILE A 240
ASP A 239
 None
 1.21A 6cbdA-3ue9A:
1.9		 6cbdA-3ue9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3ue9 ADENYLOSUCCINATE
SYNTHETASE
(Burkholderia
thailandensis) 		3 / 3 HIS A 178
ASN A 174
LEU A 171
 None
 0.83A 6f7lB-3ue9A:
undetectable		 6f7lB-3ue9A:
23.06