SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uet'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 10 VAL A 169
TRP A 188
LEU A 156
TYR A 152
TYR A 192
 None
 1.33A 1pbcA-3uetA:
undetectable		 1pbcA-3uetA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 8 ARG A 115
HIS A 124
SER A 120
ARG A 122
 None
 1.36A 1u1jA-3uetA:
7.0		 1u1jA-3uetA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 8 ARG A 234
SER A 205
ARG A  22
VAL A 211
 None
 1.19A 1u1jA-3uetA:
7.0		 1u1jA-3uetA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WB9_A_CYSA301_0
(GLUTATHIONE
TRANSFERASE SIGMA
CLASS)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 5 TYR A 192
GLY A 208
ARG A 234
TYR A 278
 None
 1.01A 2wb9A-3uetA:
undetectable		 2wb9A-3uetA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.21A 2zj0D-3uetA:
undetectable		 2zj0D-3uetA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 5 SER A 227
ARG A 212
PRO A 230
VAL A 275
 None
 1.34A 3sufC-3uetA:
undetectable		 3sufC-3uetA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 8 GLU A 419
SER A 464
ARG A 445
VAL A 461
 None
 1.28A 4d32A-3uetA:
undetectable
4d32B-3uetA:
undetectable		 4d32A-3uetA:
21.99
4d32B-3uetA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 6 ARG A 346
GLY A 344
GLU A 349
GLN A 338
 None
 1.31A 4g0vB-3uetA:
undetectable		 4g0vB-3uetA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 7 PRO A 326
SER A 327
VAL A  64
TRP A  67
 None
 1.35A 4kmmA-3uetA:
undetectable		 4kmmA-3uetA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 11 LEU A 373
ALA A 473
LEU A 395
VAL A 461
LEU A 421
 None
 1.10A 4p65C-3uetA:
undetectable
4p65D-3uetA:
undetectable
4p65J-3uetA:
undetectable
4p65L-3uetA:
undetectable		 4p65C-3uetA:
4.32
4p65D-3uetA:
4.06
4p65J-3uetA:
4.06
4p65L-3uetA:
4.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 11 LEU A 395
VAL A 461
LEU A 421
LEU A 373
ALA A 473
 None
 1.10A 4p65B-3uetA:
undetectable
4p65D-3uetA:
undetectable
4p65G-3uetA:
undetectable
4p65H-3uetA:
undetectable		 4p65B-3uetA:
4.06
4p65D-3uetA:
4.06
4p65G-3uetA:
4.32
4p65H-3uetA:
4.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 SER A 319
GLU A  30
ASP A 379
ILE A 412
SER A 227
 None
 1.25A 4uroA-3uetA:
undetectable		 4uroA-3uetA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 8 GLU A 419
SER A 464
ARG A 445
VAL A 461
 None
 1.22A 4v3yA-3uetA:
undetectable
4v3yB-3uetA:
undetectable		 4v3yA-3uetA:
21.99
4v3yB-3uetA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		3 / 3 VAL A  79
ALA A  77
PHE A 167
 None
 0.93A 4w5nA-3uetA:
2.7		 4w5nA-3uetA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		3 / 3 ASN A  16
ALA A  15
ARG A 417
 None
 0.78A 5cvtB-3uetA:
2.6		 5cvtB-3uetA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.27A 5hm8A-3uetA:
2.1		 5hm8A-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.27A 5hm8B-3uetA:
2.1		 5hm8B-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.28A 5hm8C-3uetA:
2.1		 5hm8C-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.28A 5hm8D-3uetA:
2.1		 5hm8D-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.28A 5hm8E-3uetA:
undetectable		 5hm8E-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.28A 5hm8F-3uetA:
undetectable		 5hm8F-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.28A 5hm8G-3uetA:
undetectable		 5hm8G-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.28A 5hm8H-3uetA:
2.2		 5hm8H-3uetA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 ILE A  80
GLY A 129
TYR A  32
GLU A 237
ILE A 204
 None
None
None
GAL  A 504 (-3.5A)
None
 1.19A 5igvA-3uetA:
undetectable		 5igvA-3uetA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 GLY A 342
ARG A 444
GLY A 315
GLY A  75
GLY A  74
 None
 0.77A 5koxA-3uetA:
undetectable		 5koxA-3uetA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 8 ILE A 286
LEU A 322
MET A  31
LEU A 320
 None
 1.04A 5u4sB-3uetA:
undetectable		 5u4sB-3uetA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 8 SER A 464
ARG A 445
VAL A 461
GLU A 419
 None
 1.23A 5uo7A-3uetA:
undetectable
5uo7B-3uetA:
undetectable		 5uo7A-3uetA:
22.08
5uo7B-3uetA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 LEU A 311
GLY A 315
LEU A 395
ARG A 444
ILE A 408
 None
 1.24A 6bxmA-3uetA:
undetectable		 6bxmA-3uetA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_A_NCTA405_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		4 / 6 TYR A 148
THR A 138
CYH A  90
THR A  97
 None
 1.39A 6cnkA-3uetA:
0.0
6cnkB-3uetA:
undetectable		 6cnkA-3uetA:
11.33
6cnkB-3uetA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_1
(-)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.23A 6f3mB-3uetA:
undetectable		 6f3mB-3uetA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)		 3uet ALPHA-1,3/4-FUCOSIDA
SE
(Bifidobacterium
longum) 		5 / 12 THR A  82
ASP A  87
HIS A  99
LEU A  91
PHE A 291
 None
 1.24A 6f3mD-3uetA:
undetectable		 6f3mD-3uetA:
22.11