SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
3uf5 MACROPHAGE
COLONY-STIMULATING
FACTOR 1

(Mus
musculus)
3 / 3 LEU A 111
PRO A 110
LEU A 114
None
0.54A 2po7B-3uf5A:
undetectable
2po7B-3uf5A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)
3uf5 MACROPHAGE
COLONY-STIMULATING
FACTOR 1

(Mus
musculus)
3 / 3 LEU A 111
PRO A 110
LEU A 114
None
0.51A 3hcrA-3uf5A:
undetectable
3hcrA-3uf5A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)
3uf5 MACROPHAGE
COLONY-STIMULATING
FACTOR 1

(Mus
musculus)
4 / 5 LEU A 111
PRO A 110
LEU A 114
ILE A  23
None
1.02A 4klrA-3uf5A:
undetectable
4klrA-3uf5A:
17.96