SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uf6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 ALA A  75
HIS A 100
ALA A  21
THR A  65
ILE A  92
 None
 1.23A 1gtnB-3uf6A:
undetectable
1gtnC-3uf6A:
undetectable		 1gtnB-3uf6A:
15.97
1gtnC-3uf6A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 ALA A  75
HIS A 100
ALA A  21
THR A  65
ILE A  92
 None
 1.24A 1gtnH-3uf6A:
0.1
1gtnI-3uf6A:
undetectable		 1gtnH-3uf6A:
15.97
1gtnI-3uf6A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 153
HIS A 191
ILE A 230
ILE A 148
ALA A 147
 None
 1.02A 2bxcA-3uf6A:
undetectable		 2bxcA-3uf6A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 129
ILE A 230
ALA A 167
ALA A 226
LEU A 240
 None
 1.23A 2japA-3uf6A:
6.8		 2japA-3uf6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 129
ILE A 230
ALA A 167
ALA A 226
LEU A 240
 None
 1.25A 2japB-3uf6A:
5.3		 2japB-3uf6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 129
ILE A 230
ALA A 167
ALA A 226
LEU A 240
 None
 1.23A 2japC-3uf6A:
6.9		 2japC-3uf6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 129
ILE A 230
ALA A 167
ALA A 226
LEU A 240
 None
 1.24A 2japD-3uf6A:
6.8		 2japD-3uf6A:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 6 LEU A 285
MET A 136
MET A  98
LEU A 114
 None
COD  A 289 (-4.7A)
None
None
 1.32A 2oz7A-3uf6A:
undetectable		 2oz7A-3uf6A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 SER A 199
LEU A 204
ILE A 208
SER A 222
GLY A 224
 None
 1.10A 3ijxB-3uf6A:
undetectable
3ijxD-3uf6A:
undetectable		 3ijxB-3uf6A:
21.22
3ijxD-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 ILE A 208
SER A 222
GLY A 224
SER A 199
LEU A 204
 None
 1.11A 3ik6B-3uf6A:
undetectable
3ik6E-3uf6A:
undetectable		 3ik6B-3uf6A:
21.22
3ik6E-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 SER A 199
LEU A 204
ILE A 208
SER A 222
GLY A 224
 None
 1.11A 3ik6B-3uf6A:
undetectable
3ik6E-3uf6A:
undetectable		 3ik6B-3uf6A:
21.22
3ik6E-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 SER A 199
LEU A 204
ILE A 208
SER A 222
GLY A 224
 None
 1.12A 3iluB-3uf6A:
undetectable
3iluE-3uf6A:
undetectable		 3iluB-3uf6A:
21.22
3iluE-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 11 ILE A 208
SER A 222
GLY A 224
SER A 199
LEU A 204
 None
 1.10A 3iluB-3uf6A:
undetectable
3iluE-3uf6A:
undetectable		 3iluB-3uf6A:
21.22
3iluE-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASP A 270
ASN A 269
SER A 254
 COD  A 289 ( 3.8A)
COD  A 289 ( 4.4A)
COD  A 289 (-3.5A)
 0.96A 3lslA-3uf6A:
2.2
3lslD-3uf6A:
undetectable		 3lslA-3uf6A:
21.22
3lslD-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		3 / 3 SER A 254
ASP A 270
ASN A 269
 COD  A 289 (-3.5A)
COD  A 289 ( 3.8A)
COD  A 289 ( 4.4A)
 0.98A 3lslA-3uf6A:
2.2
3lslD-3uf6A:
undetectable		 3lslA-3uf6A:
21.22
3lslD-3uf6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 10 ALA A 226
LEU A 229
ILE A 131
ALA A 118
VAL A 245
 None
 1.38A 3r9cA-3uf6A:
undetectable		 3r9cA-3uf6A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 5 PHE A 192
ALA A 152
THR A 132
LEU A 168
 None
 1.13A 3t3zC-3uf6A:
undetectable		 3t3zC-3uf6A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 5 LYS A 275
LEU A 276
GLU A  30
LEU A  34
 None
 1.36A 4k4yA-3uf6A:
undetectable		 4k4yA-3uf6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 4 LYS A 275
LEU A 276
GLU A  30
LEU A  34
 None
 1.38A 4k4yE-3uf6A:
undetectable		 4k4yE-3uf6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 5 LYS A 275
LEU A 276
GLU A  30
LEU A  34
 None
 1.36A 4k4yI-3uf6A:
undetectable		 4k4yI-3uf6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 196
ILE A 119
LEU A 281
GLY A 160
ILE A 161
 None
 1.16A 4o1eA-3uf6A:
undetectable		 4o1eA-3uf6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLU A 174
VAL A 175
PRO A 201
SER A 222
GLY A 224
 None
 1.22A 4olfA-3uf6A:
3.8		 4olfA-3uf6A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 6 TRP A  62
LEU A  36
PHE A  43
VAL A  88
 None
 1.08A 4udaA-3uf6A:
undetectable		 4udaA-3uf6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE A 196
SER A 222
LEU A 229
ILE A 228
 None
 0.88A 4xtaB-3uf6A:
undetectable		 4xtaB-3uf6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		3 / 3 THR A 282
HIS A 100
LEU A 108
 None
 0.77A 5axdA-3uf6A:
undetectable		 5axdA-3uf6A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 6 TYR A 241
ILE A 122
VAL A 245
ALA A 250
 COD  A 289 (-4.1A)
None
None
None
 0.78A 5cu6A-3uf6A:
undetectable		 5cu6A-3uf6A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 7 TYR A 241
ILE A 122
VAL A 245
ALA A 250
 COD  A 289 (-4.1A)
None
None
None
 0.78A 5osrA-3uf6A:
undetectable		 5osrA-3uf6A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3uf6 LMO1369 PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLN A 186
VAL A 175
GLU A 173
ALA A 223
 None
 1.13A 6djzB-3uf6A:
undetectable		 6djzB-3uf6A:
23.15