SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ufb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 TYR A 124
ARG A 136
GLN A  77
None
0.94A 1tw4A-3ufbA:
undetectable
1tw4A-3ufbA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
5 / 12 LEU A 121
ILE A 164
ILE A  96
LEU A 101
ARG A 158
None
1.17A 1tw4B-3ufbA:
undetectable
1tw4B-3ufbA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
5 / 11 VAL A 360
ILE A 341
LEU A 338
LEU A 386
LEU A 380
None
1.21A 2a15A-3ufbA:
undetectable
2a15A-3ufbA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 8 THR A 201
GLY A 227
ALA A 225
VAL A 361
None
0.85A 2a1hA-3ufbA:
undetectable
2a1hB-3ufbA:
undetectable
2a1hA-3ufbA:
20.58
2a1hB-3ufbA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
5 / 12 GLY A 260
GLY A 227
ALA A 225
PHE A 236
PRO A 282
None
1.09A 2dpmA-3ufbA:
7.8
2dpmA-3ufbA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 7 MET A 342
LEU A 482
PRO A 310
VAL A 362
None
1.36A 2hrcA-3ufbA:
undetectable
2hrcA-3ufbA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
5 / 10 ILE A 105
LEU A 157
ASN A 153
ASN A 106
ILE A 152
None
1.20A 2nnhB-3ufbA:
undetectable
2nnhB-3ufbA:
21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
7 / 12 ALA A 225
GLY A 227
GLY A 230
SER A 289
ASN A 309
PRO A 311
PHE A 337
None
0.50A 2okcA-3ufbA:
34.2
2okcA-3ufbA:
31.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
7 / 12 ALA A 225
GLY A 227
GLY A 230
SER A 289
ASN A 309
PRO A 311
PHE A 337
None
0.46A 2okcB-3ufbA:
34.1
2okcB-3ufbA:
31.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
10 / 12 THR A 201
ALA A 225
GLY A 227
THR A 228
GLY A 230
ASN A 288
LEU A 290
ASN A 309
PRO A 311
PHE A 337
None
0.73A 2y7hB-3ufbA:
28.1
2y7hB-3ufbA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
7 / 12 THR A 201
ALA A 225
THR A 228
GLY A 229
ASN A 309
PRO A 311
PHE A 337
None
0.98A 2y7hB-3ufbA:
28.1
2y7hB-3ufbA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
9 / 12 THR A 201
ALA A 225
GLY A 227
THR A 228
GLY A 230
LEU A 290
ASN A 309
PRO A 311
PHE A 337
None
0.66A 2y7hC-3ufbA:
29.2
2y7hC-3ufbA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
7 / 12 THR A 201
ALA A 225
THR A 228
GLY A 229
ASN A 309
PRO A 311
PHE A 337
None
0.98A 2y7hC-3ufbA:
29.2
2y7hC-3ufbA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 6 MET A 335
SER A 373
PRO A 363
GLY A 365
None
1.41A 2y7pA-3ufbA:
undetectable
2y7pA-3ufbA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 ARG A 150
ASP A  36
ASP A  44
None
0.72A 3jayA-3ufbA:
7.4
3jayA-3ufbA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 ARG A 150
ASP A  36
ASP A  44
None
0.75A 3jb2A-3ufbA:
7.2
3jb2A-3ufbA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 ARG A 150
ASP A  36
ASP A  44
None
0.84A 3jb3A-3ufbA:
5.9
3jb3A-3ufbA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 8 SER A 172
HIS A 176
GLU A  68
GLU A  72
None
0.89A 3sg9B-3ufbA:
undetectable
3sg9B-3ufbA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 PRO A 415
THR A 416
LEU A 380
None
0.66A 3ttrA-3ufbA:
undetectable
3ttrA-3ufbA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 ARG A 291
PHE A 292
PRO A 293
None
0.38A 3zoaB-3ufbA:
undetectable
3zoaB-3ufbA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 6 GLY A 405
VAL A 361
PRO A 363
GLY A 313
None
0.80A 4dxuA-3ufbA:
undetectable
4dxuA-3ufbA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 7 GLY A 405
VAL A 361
PRO A 363
GLY A 313
None
0.78A 4forA-3ufbA:
undetectable
4forA-3ufbA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
5 / 12 ILE A 389
VAL A 205
LEU A 392
PRO A 393
VAL A 396
None
1.00A 4gc9A-3ufbA:
11.3
4gc9A-3ufbA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 ARG A 412
GLU A 379
ARG A 302
None
0.97A 4mwvA-3ufbA:
undetectable
4mwvA-3ufbA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 5 SER A 179
ARG A 136
GLY A 278
GLU A 280
None
1.17A 5cdqA-3ufbA:
undetectable
5cdqB-3ufbA:
undetectable
5cdqC-3ufbA:
undetectable
5cdqA-3ufbA:
22.98
5cdqB-3ufbA:
17.44
5cdqC-3ufbA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 5 SER A 179
ARG A 136
GLY A 278
GLU A 280
None
1.18A 5cdqR-3ufbA:
undetectable
5cdqS-3ufbA:
undetectable
5cdqT-3ufbA:
undetectable
5cdqR-3ufbA:
22.98
5cdqS-3ufbA:
17.44
5cdqT-3ufbA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
3 / 3 THR A 201
ASP A 223
GLU A 261
None
0.76A 5fa8A-3ufbA:
11.7
5fa8A-3ufbA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
5 / 12 PHE A 169
LEU A  61
ASN A 273
THR A  17
GLU A 237
None
1.47A 5v1tA-3ufbA:
undetectable
5v1tA-3ufbA:
23.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
6 / 12 ALA A 225
GLY A 227
THR A 228
GLY A 229
LEU A 290
PHE A 337
None
0.86A 5ybbA-3ufbA:
36.9
5ybbA-3ufbA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
6 / 12 ALA A 225
GLY A 227
THR A 228
GLY A 230
PRO A 266
ASN A 309
None
1.01A 5ybbA-3ufbA:
36.9
5ybbA-3ufbA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
6 / 12 ALA A 225
GLY A 227
THR A 228
LEU A 290
ASN A 309
PHE A 337
None
0.70A 5ybbA-3ufbA:
36.9
5ybbA-3ufbA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_B_SAMB601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
7 / 12 THR A 201
ASP A 223
THR A 228
LEU A 290
ASN A 309
PRO A 311
PHE A 337
None
0.66A 5ybbB-3ufbA:
36.3
5ybbB-3ufbA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_B_SAMB601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
6 / 12 THR A 201
ASP A 223
THR A 228
PRO A 266
ASN A 309
PRO A 311
None
0.81A 5ybbB-3ufbA:
36.3
5ybbB-3ufbA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 7 ALA A 225
GLY A 227
GLY A 229
ASN A 288
None
0.67A 5ybbB-3ufbA:
36.3
5ybbB-3ufbA:
39.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3ufb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT

(Vibrio
vulnificus)
4 / 7 ALA A 225
GLY A 227
GLY A 229
GLU A 261
None
0.69A 5ybbB-3ufbA:
36.3
5ybbB-3ufbA:
39.67