SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ufc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 GLU X  95
ILE X  28
LEU X  43
GLY X  93
ILE X  94
 None
 1.25A 2e7fA-3ufcX:
undetectable		 2e7fA-3ufcX:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 GLU X  95
ILE X  28
LEU X  43
GLY X  93
ILE X  94
 None
 1.22A 2e7fB-3ufcX:
undetectable		 2e7fB-3ufcX:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 GLU X  95
ILE X  28
LEU X  43
GLY X  93
ILE X  94
 None
 1.25A 2ogyA-3ufcX:
undetectable		 2ogyA-3ufcX:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 GLU X  95
ILE X  28
LEU X  43
GLY X  93
ILE X  94
 None
 1.24A 2ogyB-3ufcX:
undetectable		 2ogyB-3ufcX:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 GLY X 223
LEU X 129
SER X 130
SER X  80
LEU X 115
 None
 1.37A 3bxoA-3ufcX:
undetectable		 3bxoA-3ufcX:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 ILE X  55
ASN X  13
VAL X 105
GLY X 106
 None
 0.67A 3em0B-3ufcX:
undetectable		 3em0B-3ufcX:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 9 GLN X  27
GLU X  99
LEU X   7
LEU X  77
ILE X  55
 None
 1.37A 3nbqA-3ufcX:
undetectable		 3nbqA-3ufcX:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 GLY X 103
ILE X  16
LEU X  24
GLU X  23
 None
 0.80A 4mwzB-3ufcX:
undetectable		 4mwzB-3ufcX:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 9 LEU X 193
GLY X 231
GLY X 225
ILE X 132
ILE X 200
 None
 0.93A 4rvjD-3ufcX:
undetectable		 4rvjD-3ufcX:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 VAL X 109
PRO X  98
PHE X  52
ILE X  28
GLN X  27
 None
 1.35A 5hgcA-3ufcX:
undetectable		 5hgcA-3ufcX:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ILE X  16
PRO X  17
ILE X  68
 None
 0.45A 5hw8F-3ufcX:
undetectable		 5hw8F-3ufcX:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 10 ASN X 124
PHE X 126
ALA X 216
GLY X 219
ILE X 132
 None
 1.11A 6bniA-3ufcX:
undetectable		 6bniA-3ufcX:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 10 ASN X 124
PHE X 126
ALA X 216
GLY X 219
ILE X 132
 None
 1.07A 6bniB-3ufcX:
undetectable		 6bniB-3ufcX:
14.29