SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ufg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 ARG A 261
ASP A  61
ASN A  67
 None
ATP  A 288 (-3.7A)
None
 0.68A 1nbhA-3ufgA:
undetectable		 1nbhA-3ufgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 ARG A 261
ASP A  61
ASN A  67
 None
ATP  A 288 (-3.7A)
None
 0.65A 1nbhD-3ufgA:
undetectable		 1nbhD-3ufgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		5 / 12 LEU A  43
LEU A  40
ALA A  37
TYR A 237
LEU A 120
 None
 1.09A 1s9pA-3ufgA:
undetectable		 1s9pA-3ufgA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		5 / 12 LEU A  43
LEU A  40
ALA A  37
TYR A 237
LEU A 120
 None
 1.10A 1s9pD-3ufgA:
undetectable		 1s9pD-3ufgA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 7 THR A  33
THR A  38
SER A  42
VAL A 150
 ATP  A 288 (-3.7A)
None
None
None
 1.10A 1tv8A-3ufgA:
undetectable		 1tv8A-3ufgA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 7 THR A  33
THR A  38
SER A  42
VAL A 150
 ATP  A 288 (-3.7A)
None
None
None
 1.18A 1tv8B-3ufgA:
undetectable		 1tv8B-3ufgA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 8 THR A  33
THR A  38
SER A  42
VAL A 150
 ATP  A 288 (-3.7A)
None
None
None
 1.14A 2fb2A-3ufgA:
undetectable		 2fb2A-3ufgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 7 THR A  33
THR A  38
SER A  42
VAL A 150
 ATP  A 288 (-3.7A)
None
None
None
 1.17A 2fb2B-3ufgA:
undetectable		 2fb2B-3ufgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 6 LEU A  93
SER A  95
LEU A  99
LEU A 103
 None
 1.04A 3f33A-3ufgA:
undetectable		 3f33A-3ufgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 ARG A  58
ASP A 251
ASP A  61
 ATP  A 288 (-2.9A)
None
ATP  A 288 (-3.7A)
 0.80A 3jayA-3ufgA:
undetectable		 3jayA-3ufgA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		5 / 11 ALA A 243
ASN A 274
LEU A 271
ILE A 227
THR A 246
 None
 1.20A 3jw5A-3ufgA:
undetectable		 3jw5A-3ufgA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 8 PHE A  34
GLY A  30
ILE A 268
CYH A 240
 None
 0.93A 3ko0O-3ufgA:
undetectable
3ko0Q-3ufgA:
undetectable		 3ko0O-3ufgA:
15.08
3ko0Q-3ufgA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 8 TYR A  25
LEU A  40
TYR A 237
TYR A  52
 None
 1.25A 3po7A-3ufgA:
undetectable		 3po7A-3ufgA:
18.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		8 / 8 ALA A  31
GLY A  32
THR A  33
ARG A  58
GLN A  76
GLN A  78
GLU A 156
THR A 158
 ATP  A 288 (-3.7A)
None
ATP  A 288 (-3.7A)
ATP  A 288 (-2.9A)
ATP  A 288 ( 4.3A)
ATP  A 288 ( 4.6A)
ATP  A 288 (-3.8A)
ATP  A 288 ( 3.9A)
 0.30A 3rglA-3ufgA:
47.1		 3rglA-3ufgA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 8 LEU A 161
TRP A 179
TYR A 189
PRO A  55
 None
 0.90A 4j7uD-3ufgA:
undetectable		 4j7uD-3ufgA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 7 GLU A 229
ILE A 227
LEU A  40
ILE A 278
 None
 0.93A 4xumA-3ufgA:
undetectable		 4xumA-3ufgA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 8 VAL A 145
LEU A 283
GLY A  44
SER A  42
 None
 0.66A 5f1aA-3ufgA:
undetectable		 5f1aA-3ufgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 7 VAL A 145
LEU A 283
GLY A  44
SER A  42
 None
 0.74A 5f1aB-3ufgA:
undetectable		 5f1aB-3ufgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		4 / 5 LEU A  40
CYH A 275
CYH A 224
LEU A 271
 None
 1.33A 5mafA-3ufgA:
undetectable		 5mafA-3ufgA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 HIS A 245
ASN A 248
ALA A 252
 None
 0.32A 5n4tB-3ufgA:
undetectable		 5n4tB-3ufgA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 VAL A  53
TYR A  75
GLN A  76
 None
None
ATP  A 288 ( 4.3A)
 0.57A 5qgkA-3ufgA:
undetectable		 5qgkA-3ufgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 VAL A  53
TYR A  75
GLN A  76
 None
None
ATP  A 288 ( 4.3A)
 0.56A 5qgrA-3ufgA:
undetectable		 5qgrA-3ufgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT
(Campylobacter
jejuni) 		3 / 3 VAL A  53
TYR A  75
GLN A  76
 None
None
ATP  A 288 ( 4.3A)
 0.58A 5qgtA-3ufgA:
undetectable		 5qgtA-3ufgA:
20.53