SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ufi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3ufi HYPOTHETICAL PROTEIN
BACOVA_04980
(Bacteroides
ovatus) 		4 / 4 LEU A 232
PRO A 286
ILE A 249
LEU A 250
 None
 1.10A 1ya4C-3ufiA:
undetectable		 1ya4C-3ufiA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3ufi HYPOTHETICAL PROTEIN
BACOVA_04980
(Bacteroides
ovatus) 		4 / 7 VAL A  69
TYR A  91
GLY A  42
VAL A 174
 None
 0.90A 2y05A-3ufiA:
undetectable
2y05B-3ufiA:
undetectable		 2y05A-3ufiA:
24.10
2y05B-3ufiA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3ufi HYPOTHETICAL PROTEIN
BACOVA_04980
(Bacteroides
ovatus) 		4 / 7 ALA A 165
ALA A 163
VAL A 168
ILE A 111
 None
 0.76A 3a2qA-3ufiA:
undetectable		 3a2qA-3ufiA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3ufi HYPOTHETICAL PROTEIN
BACOVA_04980
(Bacteroides
ovatus) 		4 / 6 LYS A  37
ILE A 111
VAL A  71
LEU A 121
 MLY  A  36 (-3.0A)
None
None
None
 1.08A 4em2A-3ufiA:
undetectable		 4em2A-3ufiA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3ufi HYPOTHETICAL PROTEIN
BACOVA_04980
(Bacteroides
ovatus) 		3 / 3 GLN A 155
THR A 151
THR A 152
 MLY  A 184 ( 4.3A)
MLY  A 154 ( 4.3A)
CL  A 328 (-4.3A)
 0.75A 4fu9A-3ufiA:
undetectable		 4fu9A-3ufiA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3ufi HYPOTHETICAL PROTEIN
BACOVA_04980
(Bacteroides
ovatus) 		3 / 3 GLN A 155
THR A 151
THR A 152
 MLY  A 184 ( 4.3A)
MLY  A 154 ( 4.3A)
CL  A 328 (-4.3A)
 0.75A 4fufA-3ufiA:
undetectable		 4fufA-3ufiA:
23.20