SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ufk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 11 ALA A  55
LEU A 209
LEU A  95
SER A 163
ALA A  92
 None
 1.05A 1h9zA-3ufkA:
undetectable		 1h9zA-3ufkA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 11 ALA A  55
LEU A 209
LEU A  95
SER A 163
ALA A  92
 None
 0.99A 1ha2A-3ufkA:
undetectable		 1ha2A-3ufkA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		3 / 3 PHE A 234
TYR A 199
PRO A 230
 None
 1.03A 1mcnA-3ufkA:
4.2
1mcnB-3ufkA:
4.2
1mcnP-3ufkA:
undetectable		 1mcnA-3ufkA:
14.32
1mcnB-3ufkA:
14.32
1mcnP-3ufkA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_B_CIOB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 HIS A 755
ILE A 724
MET A 723
PHE A 720
PHE A 663
 HEC  A 909 (-3.1A)
HEC  A 909 ( 3.8A)
HEC  A 908 ( 3.7A)
HEC  A 909 (-4.4A)
HEC  A 908 ( 4.0A)
 1.26A 1xlxB-3ufkA:
undetectable		 1xlxB-3ufkA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 6 ARG A 732
SER A 733
ARG A 736
GLU A 715
 HEC  A 908 (-3.8A)
None
HEC  A 907 ( 3.2A)
None
 1.11A 2c8aC-3ufkA:
undetectable		 2c8aC-3ufkA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 7 ARG A 471
GLU A 473
ALA A 600
ALA A 611
 NTA  A 923 (-4.0A)
None
None
None
 1.03A 2ejfA-3ufkA:
undetectable		 2ejfA-3ufkA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 7 SER A 349
ALA A 333
ALA A 334
ALA A 331
GLN A 341
 None
 1.05A 3a2qA-3ufkA:
undetectable		 3a2qA-3ufkA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 7 GLY A 303
HIS A 460
CYH A 386
HIS A 365
 HEC  A 903 (-3.4A)
HEC  A 904 ( 3.1A)
HEC  A 904 (-1.8A)
HEC  A 903 ( 3.1A)
 1.21A 3ai8A-3ufkA:
undetectable		 3ai8A-3ufkA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 6 PHE A 511
TYR A 565
HIS A 503
VAL A 508
 None
 1.17A 3lb3A-3ufkA:
undetectable		 3lb3A-3ufkA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 6 PHE A 511
TYR A 565
HIS A 503
VAL A 508
 None
 1.15A 3lb3B-3ufkA:
undetectable		 3lb3B-3ufkA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWP_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 ARG A 536
GLY A 535
ASN A 539
CYH A 702
HIS A 709
 HEC  A 907 (-3.8A)
None
None
HEC  A 908 (-2.0A)
HEC  A 907 ( 3.1A)
 1.32A 3qwpA-3ufkA:
undetectable		 3qwpA-3ufkA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 7 VAL A  60
ILE A 207
ARG A 206
ILE A  97
 None
 0.87A 4lv9A-3ufkA:
undetectable		 4lv9A-3ufkA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 8 THR A 817
GLY A 806
GLY A 807
VAL A 808
 None
None
HEC  A 911 ( 4.0A)
None
 0.75A 4qvvK-3ufkA:
undetectable
4qvvL-3ufkA:
undetectable		 4qvvK-3ufkA:
12.90
4qvvL-3ufkA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 5 ILE A 430
VAL A 433
PHE A 439
CYH A 386
 HEC  A 904 ( 3.9A)
HEC  A 904 ( 3.9A)
HEC  A 905 (-4.5A)
HEC  A 904 (-1.8A)
 1.23A 4rzvA-3ufkA:
undetectable		 4rzvA-3ufkA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 5 ILE A 648
VAL A 647
CYH A 751
HIS A 728
 HEC  A 906 ( 3.8A)
HEC  A 909 (-4.6A)
HEC  A 909 (-1.9A)
HEC  A 906 ( 3.1A)
 1.01A 4rzvA-3ufkA:
undetectable		 4rzvA-3ufkA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		3 / 3 ALA A  98
TRP A 113
VAL A 114
 None
 0.31A 4w9nC-3ufkA:
undetectable		 4w9nC-3ufkA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 6 ASP A  59
PRO A  80
THR A  74
VAL A  72
 None
 1.00A 4yoaA-3ufkA:
undetectable		 4yoaA-3ufkA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 ALA A 423
PRO A 425
GLY A 429
GLY A 432
ALA A 387
 None
 1.00A 5c0oG-3ufkA:
undetectable		 5c0oG-3ufkA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		4 / 7 THR A 296
ASP A 293
GLY A 321
TYR A 324
 None
CA  A 912 ( 3.1A)
None
HEC  A 902 ( 4.2A)
 0.90A 5hwaA-3ufkA:
undetectable		 5hwaA-3ufkA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		3 / 3 GLY A 274
GLY A 275
GLN A 212
 None
 0.47A 5imsA-3ufkA:
undetectable		 5imsA-3ufkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 ALA A 308
GLY A 312
ALA A 304
LEU A 384
ALA A 315
 None
 1.29A 5jglB-3ufkA:
undetectable		 5jglB-3ufkA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 SER A 698
GLY A 628
GLY A 594
THR A 467
ALA A 693
 None
 1.15A 5kpcB-3ufkA:
undetectable		 5kpcB-3ufkA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 GLY A 520
GLY A 588
GLY A 590
ASP A 484
VAL A 485
 None
 0.97A 5njvD-3ufkA:
undetectable		 5njvD-3ufkA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3ufk UNDA
(Shewanella
sp.
HRCR_06) 		5 / 12 LEU A 478
ASN A 630
GLY A 628
VAL A 627
LEU A 545
 None
 1.14A 5uc1B-3ufkA:
undetectable		 5uc1B-3ufkA:
7.48