SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ugg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 8 GLY A  90
THR A  61
GLY A  58
ASP A  53
 None
None
NAG  A 547 ( 3.9A)
NAG  A 547 (-3.6A)
 0.80A 1aegA-3uggA:
undetectable		 1aegA-3uggA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		5 / 8 ASP A 214
TYR A 283
ARG A 325
TYR A 278
THR A 288
 None
 1.38A 1ceaA-3uggA:
undetectable
1ceaB-3uggA:
undetectable		 1ceaA-3uggA:
10.38
1ceaB-3uggA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 7 ASP A 214
TYR A 283
ARG A 325
TYR A 278
 None
 1.44A 1ceaB-3uggA:
undetectable		 1ceaB-3uggA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 7 ASP A 214
TYR A 283
ARG A 325
TYR A 278
 None
 1.38A 1cebB-3uggA:
undetectable		 1cebB-3uggA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 8 PHE A 448
ASP A 279
ILE A 500
THR A 501
 None
 0.87A 1hmyA-3uggA:
undetectable		 1hmyA-3uggA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 ASP A 307
VAL A 461
SER A 462
GLN A  18
 None
 1.49A 1n2xB-3uggA:
undetectable		 1n2xB-3uggA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		5 / 10 GLY A 149
VAL A 150
TYR A 186
LEU A 196
ALA A 146
 None
 0.89A 1pbcA-3uggA:
undetectable		 1pbcA-3uggA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		5 / 12 GLN A 464
PHE A 468
ARG A 325
SER A 502
LEU A 306
 None
 1.38A 1ynnC-3uggA:
undetectable		 1ynnC-3uggA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 TRP A 302
LYS A 240
PRO A  34
 None
 1.49A 2dqyB-3uggA:
undetectable		 2dqyB-3uggA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 THR A 153
ASP A 244
SER A 242
 None
DQR  A 800 (-3.6A)
None
 0.81A 2nxeA-3uggA:
undetectable		 2nxeA-3uggA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		5 / 12 PHE A  47
GLY A  94
ALA A 122
ASP A  33
PRO A  37
 None
None
None
DQR  A 800 (-3.0A)
None
 1.11A 2zulA-3uggA:
undetectable		 2zulA-3uggA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 THR A 507
SER A 459
LYS A 463
 None
 1.05A 3aocC-3uggA:
undetectable		 3aocC-3uggA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAM_B_LLLB500_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		5 / 11 ASP A 249
CYH A 212
ASP A 157
SER A  93
ASP A  33
 None
None
DQR  A 800 (-3.1A)
DQR  A 800 (-3.0A)
DQR  A 800 (-3.0A)
 1.21A 3hamB-3uggA:
0.0		 3hamB-3uggA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 PHE A 478
TYR A 435
ILE A 378
LEU A 531
 None
 1.36A 3sueC-3uggA:
0.8		 3sueC-3uggA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 TRP A  30
VAL A  91
TRP A  57
 None
None
DQR  A 800 ( 3.9A)
 1.18A 3zq8C-3uggA:
undetectable
3zq8D-3uggA:
undetectable		 3zq8C-3uggA:
4.17
3zq8D-3uggA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		5 / 12 ASP A 312
SER A 308
TRP A  10
THR A 507
ALA A 458
 None
 1.46A 4dajB-3uggA:
undetectable		 4dajB-3uggA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 SER A 286
TYR A 278
PRO A  37
 None
 0.91A 4lbgA-3uggA:
undetectable		 4lbgA-3uggA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 SER A 286
TYR A 283
PRO A  37
 None
 0.92A 4lbgA-3uggA:
undetectable		 4lbgA-3uggA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 ASP A 451
ASN A 521
SER A 421
 None
NAG  A 553 (-1.8A)
None
 0.84A 4obwA-3uggA:
undetectable		 4obwA-3uggA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 ASP A 485
LEU A 483
ARG A 325
THR A  20
 None
 1.48A 4p3qA-3uggA:
undetectable		 4p3qA-3uggA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 4 ALA A 146
VAL A 116
GLY A 110
THR A 109
 None
 1.15A 4ubeA-3uggA:
undetectable		 4ubeA-3uggA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 ALA A 122
TRP A 135
VAL A 136
 None
 0.27A 4w9nC-3uggA:
undetectable		 4w9nC-3uggA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 THR A 207
HIS A 237
LEU A 201
 None
 0.82A 5axdA-3uggA:
undetectable		 5axdA-3uggA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 8 THR A 109
LEU A 119
ILE A 173
LEU A 144
 None
 0.81A 5g48A-3uggA:
undetectable		 5g48A-3uggA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 8 THR A 109
LEU A 119
ILE A 173
PRO A 147
 None
 0.89A 5g48A-3uggA:
undetectable		 5g48A-3uggA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		3 / 3 ASN A 336
TYR A 251
CYH A 499
 None
 1.03A 5lsuB-3uggA:
undetectable		 5lsuB-3uggA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 4 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.34A 5n0rA-3uggA:
undetectable		 5n0rA-3uggA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 4 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.34A 5n0sA-3uggA:
undetectable		 5n0sA-3uggA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.31A 5n0tA-3uggA:
undetectable		 5n0tA-3uggA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 4 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.35A 5n0wA-3uggA:
undetectable		 5n0wA-3uggA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.38A 5n0wB-3uggA:
undetectable		 5n0wB-3uggA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 4 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.38A 5n0xA-3uggA:
undetectable		 5n0xA-3uggA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 SER A 459
ALA A 458
GLN A  18
THR A 507
 None
 1.38A 5n4iA-3uggA:
undetectable		 5n4iA-3uggA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 7 SER A 455
THR A 430
VAL A 432
ILE A 488
 None
 1.23A 5vkqC-3uggA:
undetectable
5vkqD-3uggA:
undetectable		 5vkqC-3uggA:
15.42
5vkqD-3uggA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 8 PRO A 142
THR A 109
TYR A  86
PRO A 147
 None
 1.35A 5x2sI-3uggA:
undetectable
5x2sJ-3uggA:
undetectable
5x2sK-3uggA:
undetectable		 5x2sI-3uggA:
11.72
5x2sJ-3uggA:
15.16
5x2sK-3uggA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE
(Pachysandra
terminalis) 		4 / 5 LEU A 516
VAL A 370
GLU A 535
LEU A 376
 None
 0.83A 5xooB-3uggA:
undetectable		 5xooB-3uggA:
11.43