SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ugm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 4 LEU A 866
SER A 910
LEU A 891
LEU A 902
 None
 0.84A 1yajA-3ugmA:
undetectable		 1yajA-3ugmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 VAL A 363
SER A 333
VAL A 329
SER A 367
 None
 1.05A 2j9cA-3ugmA:
undetectable
2j9cB-3ugmA:
undetectable
2j9cC-3ugmA:
undetectable		 2j9cA-3ugmA:
7.05
2j9cB-3ugmA:
7.05
2j9cC-3ugmA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 VAL A 668
SER A 638
VAL A 634
SER A 672
 None
 1.18A 2j9cA-3ugmA:
undetectable
2j9cB-3ugmA:
undetectable
2j9cC-3ugmA:
undetectable		 2j9cA-3ugmA:
7.05
2j9cB-3ugmA:
7.05
2j9cC-3ugmA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 VAL A 736
SER A 706
VAL A 702
SER A 740
 None
 1.11A 2j9cA-3ugmA:
undetectable
2j9cB-3ugmA:
undetectable
2j9cC-3ugmA:
undetectable		 2j9cA-3ugmA:
7.05
2j9cB-3ugmA:
7.05
2j9cC-3ugmA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 628
ALA A 635
ILE A 602
GLY A 642
LEU A 622
 None
 1.01A 2o4nA-3ugmA:
undetectable		 2o4nA-3ugmA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 612
GLN A 582
THR A 580
HIS A 592
 None
 1.03A 2zj0B-3ugmA:
undetectable		 2zj0B-3ugmA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 612
GLN A 583
THR A 580
HIS A 592
 None
 1.14A 2zj0B-3ugmA:
undetectable		 2zj0B-3ugmA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 884
GLN A 854
THR A 852
HIS A 864
 None
 1.17A 2zj0B-3ugmA:
undetectable		 2zj0B-3ugmA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 477
GLN A 447
THR A 445
HIS A 457
 None
 1.01A 3ce6B-3ugmA:
undetectable		 3ce6B-3ugmA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 714
GLN A 684
THR A 682
HIS A 694
 None
 1.11A 3ce6B-3ugmA:
undetectable		 3ce6B-3ugmA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 884
GLN A 854
THR A 852
HIS A 864
 None
 1.15A 3ce6B-3ugmA:
undetectable		 3ce6B-3ugmA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 612
GLN A 583
THR A 580
HIS A 592
 None
 1.18A 3ce6D-3ugmA:
undetectable		 3ce6D-3ugmA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 884
GLN A 854
THR A 852
HIS A 864
 None
 1.13A 3ce6D-3ugmA:
undetectable		 3ce6D-3ugmA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 4 ARG A 414
ASP A 437
GLY A 370
THR A 377
 None
 1.44A 3k4vB-3ugmA:
undetectable		 3k4vB-3ugmA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 4 ARG A 719
ASP A 742
GLY A 675
THR A 682
 None
 1.47A 3k4vB-3ugmA:
undetectable		 3k4vB-3ugmA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 612
GLN A 583
THR A 580
HIS A 592
 None
 1.20A 3n58C-3ugmA:
undetectable		 3n58C-3ugmA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 5 LEU A 884
GLN A 854
THR A 852
HIS A 864
 None
 1.08A 3n58C-3ugmA:
undetectable		 3n58C-3ugmA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 748
LEU A 730
GLY A 778
ALA A 773
SER A 774
 None
 1.05A 3n8xB-3ugmA:
undetectable		 3n8xB-3ugmA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 748
LEU A 730
GLY A 778
ALA A 773
SER A 774
 None
 1.08A 3n8zA-3ugmA:
undetectable		 3n8zA-3ugmA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 748
LEU A 730
GLY A 778
ALA A 773
SER A 774
 None
 1.06A 3nt1A-3ugmA:
undetectable		 3nt1A-3ugmA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 714
LEU A 696
GLY A 744
ALA A 739
SER A 740
 None
 1.10A 3nt1B-3ugmA:
undetectable		 3nt1B-3ugmA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 748
LEU A 730
GLY A 778
ALA A 773
SER A 774
 None
 1.05A 3nt1B-3ugmA:
undetectable		 3nt1B-3ugmA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 986
LEU A 968
GLY A1015
ALA A1011
SER A1012
 None
 1.24A 3pghA-3ugmA:
undetectable		 3pghA-3ugmA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 4 LYS A 711
GLN A 746
ILE A 738
LEU A 721
 None
 1.48A 3qt0A-3ugmA:
undetectable		 3qt0A-3ugmA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 9 LEU A 968
ALA A 975
ILE A 942
GLY A 982
LEU A 962
 None
 1.09A 3u7sA-3ugmA:
undetectable		 3u7sA-3ugmA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		4 / 6 ALA A 883
ALA A 849
LEU A 884
THR A 852
 None
 0.90A 4dtzA-3ugmA:
undetectable		 4dtzA-3ugmA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 9 GLY A 525
HIS A 524
VAL A 566
VAL A 547
LEU A 544
 None
 1.10A 4qd3A-3ugmA:
undetectable		 4qd3A-3ugmA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 12 LEU A 487
HIS A 491
VAL A 498
ILE A 501
LEU A 516
 None
 1.17A 4yvpB-3ugmA:
undetectable		 4yvpB-3ugmA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		3 / 3 GLY A 593
LEU A 594
HIS A 592
 None
 0.67A 5u63A-3ugmA:
undetectable		 5u63A-3ugmA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		3 / 3 GLY A 593
LEU A 594
HIS A 592
 None
 0.62A 5u63B-3ugmA:
undetectable		 5u63B-3ugmA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 9 ALA A 705
SER A 706
GLY A 710
ALA A 739
GLY A 744
 None
 1.14A 6bklE-3ugmA:
undetectable
6bklF-3ugmA:
undetectable
6bklG-3ugmA:
undetectable
6bklH-3ugmA:
undetectable		 6bklE-3ugmA:
2.43
6bklF-3ugmA:
2.43
6bklG-3ugmA:
2.43
6bklH-3ugmA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 9 SER A 706
GLY A 710
ALA A 739
SER A 740
GLY A 744
 None
 1.17A 6bklE-3ugmA:
undetectable
6bklF-3ugmA:
undetectable
6bklG-3ugmA:
undetectable
6bklH-3ugmA:
undetectable		 6bklE-3ugmA:
2.43
6bklF-3ugmA:
2.43
6bklG-3ugmA:
2.43
6bklH-3ugmA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3ugm TAL EFFECTOR
AVRBS3/PTHA
(Xanthomonas
oryzae) 		5 / 10 VAL A 547
VAL A 581
LEU A 551
GLN A 582
CYH A 555
 None
 1.31A 6czmE-3ugmA:
undetectable
6czmF-3ugmA:
undetectable		 6czmE-3ugmA:
17.69
6czmF-3ugmA:
17.69