SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ugs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ugs UNDECAPRENYL
PYROPHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 6 ARG B 144
ASP B  99
GLY B  98
ASP B 136
 None
 1.25A 5hp1A-3ugsB:
undetectable		 5hp1A-3ugsB:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ugs UNDECAPRENYL
PYROPHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 6 ARG B 144
ASP B  99
GLY B  98
ASP B 136
 None
 1.29A 5hp1C-3ugsB:
undetectable		 5hp1C-3ugsB:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ugs UNDECAPRENYL
PYROPHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		3 / 3 GLY B  33
VAL B 173
MET B  11
 None
None
FFT  B 401 (-4.3A)
 0.47A 5ycpA-3ugsB:
undetectable		 5ycpA-3ugsB:
15.70