SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ugv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 7 LEU A  79
THR A  42
GLY A  76
LEU A  74
 None
 0.89A 1gtiB-3ugvA:
undetectable		 1gtiB-3ugvA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 8 LEU A 124
VAL A 316
GLY A 130
TRP A 113
 None
 0.93A 1jlbA-3ugvA:
undetectable		 1jlbA-3ugvA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 7 LEU A 100
ILE A 103
ALA A  59
PRO A  54
 None
 0.91A 1oniB-3ugvA:
undetectable
1oniC-3ugvA:
undetectable		 1oniB-3ugvA:
16.24
1oniC-3ugvA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		3 / 3 ASP A 330
LEU A 333
HIS A 304
 None
None
MG  A 500 ( 4.9A)
 0.69A 1qknA-3ugvA:
undetectable		 1qknA-3ugvA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 7 TYR A  51
VAL A 309
GLY A 310
THR A 303
 None
 0.88A 2a1mA-3ugvA:
undetectable		 2a1mA-3ugvA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 8 LYS A 136
HIS A 321
GLU A 225
ALA A 198
 None
 0.94A 2bnnA-3ugvA:
undetectable
2bnnB-3ugvA:
undetectable		 2bnnA-3ugvA:
18.27
2bnnB-3ugvA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 ALA A 329
ASP A 330
LEU A  35
MET A 110
LEU A 354
 None
 1.09A 2jfaB-3ugvA:
undetectable		 2jfaB-3ugvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 LEU A 352
ALA A 329
GLN A 326
MET A 110
LEU A  52
 None
 1.37A 2oaxC-3ugvA:
undetectable		 2oaxC-3ugvA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		3 / 3 SER A  91
HIS A  68
ASP A  39
 None
 0.82A 2oxtA-3ugvA:
undetectable		 2oxtA-3ugvA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 4 GLY A 342
GLY A 166
GLY A 164
GLY A 162
 None
 0.53A 3bogC-3ugvA:
undetectable		 3bogC-3ugvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 4 GLY A 342
GLY A 166
GLY A 164
GLY A 162
 None
 0.42A 3bogD-3ugvA:
undetectable		 3bogD-3ugvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		3 / 3 ARG A  26
ASP A 182
ASP A 177
 None
 0.91A 3jb2A-3ugvA:
undetectable		 3jb2A-3ugvA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		3 / 3 ARG A  26
ASP A 182
ASP A 177
 None
 0.94A 3jb3A-3ugvA:
undetectable		 3jb3A-3ugvA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 7 TYR A  55
VAL A 108
ILE A  36
ARG A  89
 None
 1.22A 3ms9B-3ugvA:
undetectable		 3ms9B-3ugvA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 10 ARG A 215
ALA A 212
LEU A 246
LEU A 242
VAL A 231
 None
 1.13A 3o02A-3ugvA:
undetectable
3o02B-3ugvA:
undetectable		 3o02A-3ugvA:
21.48
3o02B-3ugvA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 10 LEU A 266
ALA A 296
GLY A 298
ILE A 299
PHE A 256
 None
 1.47A 3qpsA-3ugvA:
undetectable		 3qpsA-3ugvA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 GLY A 253
PRO A 259
GLY A 258
LEU A 273
MET A 275
 None
None
None
None
MG  A 500 ( 4.9A)
 1.33A 3r24A-3ugvA:
undetectable		 3r24A-3ugvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 LEU A 352
ALA A 329
GLN A 326
MET A 110
LEU A  52
 None
 1.39A 3vhuA-3ugvA:
undetectable		 3vhuA-3ugvA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 6 ALA A 104
LEU A  63
VAL A  64
ASP A  69
 None
 1.02A 4g24A-3ugvA:
undetectable		 4g24A-3ugvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 ILE A  40
ALA A  75
SER A  71
LEU A  74
LEU A  10
 None
 1.33A 4m11C-3ugvA:
undetectable		 4m11C-3ugvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 LEU A 352
ALA A 329
GLN A 326
MET A 110
LEU A  52
 None
 1.28A 4udaA-3ugvA:
undetectable		 4udaA-3ugvA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		3 / 3 ARG A  49
ASP A  39
TRP A 356
 None
 1.19A 4xdqA-3ugvA:
undetectable		 4xdqA-3ugvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 LEU A 352
ALA A 117
GLY A 310
ALA A 311
LEU A 344
 None
 1.09A 5jw1B-3ugvA:
undetectable		 5jw1B-3ugvA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 4 GLU A  53
PRO A  54
ILE A  36
LEU A  35
 None
 1.19A 5m45A-3ugvA:
0.2		 5m45A-3ugvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 4 GLU A  53
PRO A  54
ILE A  36
LEU A  35
 None
 1.21A 5m45D-3ugvA:
0.7		 5m45D-3ugvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 4 GLU A  53
PRO A  54
ILE A  36
LEU A  35
 None
 1.18A 5m45G-3ugvA:
undetectable		 5m45G-3ugvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 4 GLU A  53
PRO A  54
ILE A  36
LEU A  35
 None
 1.23A 5m45J-3ugvA:
undetectable		 5m45J-3ugvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 6 TYR A  51
TYR A 306
ASP A 114
HIS A 312
 None
 1.47A 5ov9A-3ugvA:
undetectable		 5ov9A-3ugvA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 7 TYR A  51
TYR A 306
ASP A 114
HIS A 312
 None
 1.47A 5ov9B-3ugvA:
undetectable		 5ov9B-3ugvA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 ASP A 355
ARG A  49
ILE A  84
ALA A  80
ALA A 119
 None
 1.12A 5vc0A-3ugvA:
undetectable		 5vc0A-3ugvA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 8 VAL A 201
ASP A 202
GLY A 206
LEU A 207
 None
MG  A 500 (-3.1A)
None
None
 0.84A 5w3jB-3ugvA:
2.5		 5w3jB-3ugvA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 8 SER A 140
GLN A 326
TYR A 138
MET A 275
 None
None
None
MG  A 500 ( 4.9A)
 1.34A 5wqpA-3ugvA:
undetectable		 5wqpA-3ugvA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 5 ALA A 105
SER A 106
GLY A 283
TYR A  85
 None
 1.26A 5yodB-3ugvA:
undetectable		 5yodB-3ugvA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		5 / 12 LEU A 124
LEU A 352
GLY A 310
TYR A 337
PRO A 347
 None
 1.10A 6ce2B-3ugvA:
undetectable		 6ce2B-3ugvA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 5 LYS A  87
GLN A  77
GLY A  45
ILE A  40
 None
 1.18A 6debB-3ugvA:
undetectable		 6debB-3ugvA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		3 / 3 TRP A 226
GLU A 229
GLU A 324
 None
 0.95A 6fhwA-3ugvA:
undetectable		 6fhwA-3ugvA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3ugv ENOLASE
(alpha
proteobacterium
BAL199) 		4 / 8 TYR A  55
GLN A 205
ASN A 255
GLU A 229
 None
 1.09A 6hzpA-3ugvA:
undetectable		 6hzpA-3ugvA:
22.51