SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uhj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 SER A 203
GLY A 279
THR A 363
ILE A 359
 None
 0.88A 1gtnD-3uhjA:
undetectable
1gtnE-3uhjA:
undetectable		 1gtnD-3uhjA:
12.46
1gtnE-3uhjA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 116
VAL A 172
GLY A 266
ILE A 149
ILE A 135
 GOL  A 487 (-3.9A)
None
None
None
None
 0.78A 1hxbA-3uhjA:
undetectable		 1hxbA-3uhjA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 LEU A 304
LEU A 379
LEU A 336
GLU A 297
LEU A 333
 None
 1.29A 1ie4A-3uhjA:
undetectable
1ie4C-3uhjA:
undetectable		 1ie4A-3uhjA:
16.45
1ie4C-3uhjA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 GLY A 114
VAL A 113
LEU A  67
LEU A 178
ALA A 136
 None
 1.03A 1pbcA-3uhjA:
undetectable		 1pbcA-3uhjA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 329
GLU A 200
CYH A 230
ALA A 194
ALA A 260
 None
 1.08A 2bm9D-3uhjA:
undetectable		 2bm9D-3uhjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 329
CYH A 230
ASP A 193
ALA A 194
ALA A 260
 None
None
ZN  A 388 (-2.2A)
None
None
 1.02A 2br4A-3uhjA:
undetectable		 2br4A-3uhjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 329
CYH A 230
ASP A 193
ALA A 194
ALA A 260
 None
None
ZN  A 388 (-2.2A)
None
None
 1.10A 2br4C-3uhjA:
undetectable		 2br4C-3uhjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A 266
SER A 196
PHE A 269
GLU A 200
 None
 1.00A 2c8aB-3uhjA:
undetectable		 2c8aB-3uhjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A 266
SER A 196
PHE A 269
GLU A 200
 None
 1.04A 2c8aD-3uhjA:
undetectable		 2c8aD-3uhjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 ILE A 280
ALA A 350
LEU A 377
ILE A 376
ILE A 338
 None
 0.93A 2w9sB-3uhjA:
undetectable		 2w9sB-3uhjA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 HIS A 281
HIS A 278
VAL A 299
HIS A 295
 None
ZN  A 388 (-3.4A)
None
ZN  A 388 ( 3.6A)
 1.03A 2wkoF-3uhjA:
undetectable		 2wkoF-3uhjA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 ARG A  61
GLY A  88
SER A 141
 None
None
GOL  A 487 (-2.6A)
 0.58A 2xctB-3uhjA:
4.0		 2xctB-3uhjA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 THR A 142
ILE A 139
GLY A 116
ALA A 150
VAL A 151
 GOL  A 487 (-3.6A)
None
GOL  A 487 (-3.9A)
None
None
 1.23A 2yvlC-3uhjA:
undetectable		 2yvlC-3uhjA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 SER A 265
GLU A 200
ASP A 193
 None
None
ZN  A 388 (-2.2A)
 0.80A 2zthA-3uhjA:
undetectable		 2zthA-3uhjA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 279
GLY A 283
LEU A 284
LEU A 307
VAL A 349
 None
 1.01A 3av6A-3uhjA:
undetectable		 3av6A-3uhjA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 VAL A  57
GLY A 112
ILE A  41
LEU A  67
THR A 138
 None
 1.16A 3bexC-3uhjA:
undetectable
3bexD-3uhjA:
undetectable		 3bexC-3uhjA:
21.00
3bexD-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.16A 3bexC-3uhjA:
undetectable
3bexD-3uhjA:
undetectable		 3bexC-3uhjA:
21.00
3bexD-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A  57
GLY A 112
ILE A  41
LEU A  67
THR A 138
 None
 1.16A 3bexE-3uhjA:
undetectable
3bexF-3uhjA:
undetectable		 3bexE-3uhjA:
21.00
3bexF-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.15A 3bexE-3uhjA:
undetectable
3bexF-3uhjA:
undetectable		 3bexE-3uhjA:
21.00
3bexF-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 VAL A  57
GLY A 112
ILE A  41
LEU A  67
THR A 138
 None
 1.19A 3bf1A-3uhjA:
undetectable
3bf1B-3uhjA:
undetectable		 3bf1A-3uhjA:
21.00
3bf1B-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.15A 3bf1A-3uhjA:
undetectable
3bf1B-3uhjA:
undetectable		 3bf1A-3uhjA:
21.00
3bf1B-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 VAL A  57
GLY A 112
ILE A  41
LEU A  67
THR A 138
 None
 1.18A 3bf1C-3uhjA:
undetectable
3bf1D-3uhjA:
undetectable		 3bf1C-3uhjA:
21.00
3bf1D-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.13A 3bf1C-3uhjA:
undetectable
3bf1D-3uhjA:
undetectable		 3bf1C-3uhjA:
21.00
3bf1D-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 VAL A  57
GLY A 112
ILE A  41
LEU A  67
THR A 138
 None
 1.17A 3bf1E-3uhjA:
undetectable
3bf1F-3uhjA:
undetectable		 3bf1E-3uhjA:
21.00
3bf1F-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.15A 3bf1E-3uhjA:
undetectable
3bf1F-3uhjA:
undetectable		 3bf1E-3uhjA:
21.00
3bf1F-3uhjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 SER A 265
GLU A 200
ASP A 193
 None
None
ZN  A 388 (-2.2A)
 0.78A 3bwyA-3uhjA:
3.9		 3bwyA-3uhjA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 280
ALA A 350
LEU A 377
ALA A 378
ILE A 338
 None
 0.95A 3dauA-3uhjA:
undetectable		 3dauA-3uhjA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 194
GLY A 190
LEU A 195
GLY A 266
SER A 265
 None
 0.92A 3g2oA-3uhjA:
undetectable		 3g2oA-3uhjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 194
GLY A 190
LEU A 195
GLY A 266
SER A 265
 None
 0.92A 3g2oB-3uhjA:
undetectable		 3g2oB-3uhjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 TYR A 159
ILE A 359
ILE A 360
ILE A 280
 None
 0.82A 3p4wC-3uhjA:
undetectable		 3p4wC-3uhjA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 234
ALA A 241
LEU A 187
ASN A 261
LEU A 264
 None
 1.18A 3p5nA-3uhjA:
undetectable		 3p5nA-3uhjA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 TYR A 153
ASP A 143
ALA A 144
ASP A 193
 None
ZN  A 388 (-3.6A)
None
ZN  A 388 (-2.2A)
 1.14A 3rodD-3uhjA:
undetectable		 3rodD-3uhjA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 HIS A 281
GLY A 302
HIS A 278
ASP A 193
GLY A 296
 None
None
ZN  A 388 (-3.4A)
ZN  A 388 (-2.2A)
None
 1.24A 4bz6C-3uhjA:
3.9		 4bz6C-3uhjA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 LEU A 287
ILE A 376
VAL A 372
GLY A 283
 None
 0.89A 4eq4B-3uhjA:
undetectable		 4eq4B-3uhjA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A  59
GLY A 115
ILE A 135
ALA A 136
ALA A 144
 None
GOL  A 487 ( 3.8A)
None
None
None
 1.03A 4kicB-3uhjA:
undetectable		 4kicB-3uhjA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A  57
GLY A 112
ILE A  41
LEU A  67
THR A 138
 None
 1.24A 4o5fA-3uhjA:
undetectable
4o5fB-3uhjA:
undetectable		 4o5fA-3uhjA:
26.49
4o5fB-3uhjA:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.24A 4o5fA-3uhjA:
undetectable
4o5fB-3uhjA:
undetectable		 4o5fA-3uhjA:
26.49
4o5fB-3uhjA:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 277
LEU A 304
GLY A 192
PHE A 301
ALA A 194
 None
 1.01A 4pclA-3uhjA:
3.5		 4pclA-3uhjA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 280
ALA A 350
LEU A 377
ALA A 378
ILE A 338
 None
 0.89A 4pssA-3uhjA:
undetectable		 4pssA-3uhjA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 280
ALA A 350
LEU A 377
ALA A 378
ILE A 338
 None
 0.83A 4psyA-3uhjA:
undetectable		 4psyA-3uhjA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.28A 4qvlV-3uhjA:
undetectable
4qvlb-3uhjA:
undetectable		 4qvlV-3uhjA:
21.54
4qvlb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.28A 4qvlH-3uhjA:
undetectable
4qvlN-3uhjA:
undetectable		 4qvlH-3uhjA:
21.54
4qvlN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 4qvnV-3uhjA:
undetectable
4qvnb-3uhjA:
undetectable		 4qvnV-3uhjA:
21.54
4qvnb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.25A 4qvpV-3uhjA:
undetectable
4qvpb-3uhjA:
undetectable		 4qvpV-3uhjA:
21.54
4qvpb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.24A 4qvpH-3uhjA:
undetectable
4qvpN-3uhjA:
undetectable		 4qvpH-3uhjA:
21.54
4qvpN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 4qvqV-3uhjA:
undetectable
4qvqb-3uhjA:
undetectable		 4qvqV-3uhjA:
21.54
4qvqb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.27A 4qvqH-3uhjA:
undetectable
4qvqN-3uhjA:
undetectable		 4qvqH-3uhjA:
21.54
4qvqN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 4qvwV-3uhjA:
undetectable
4qvwb-3uhjA:
undetectable		 4qvwV-3uhjA:
21.54
4qvwb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 4qvwH-3uhjA:
undetectable
4qvwN-3uhjA:
undetectable		 4qvwH-3uhjA:
21.54
4qvwN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 4qw1V-3uhjA:
undetectable
4qw1b-3uhjA:
undetectable		 4qw1V-3uhjA:
21.54
4qw1b-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.27A 4qw1H-3uhjA:
undetectable
4qw1N-3uhjA:
undetectable		 4qw1H-3uhjA:
21.54
4qw1N-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.27A 4qwuV-3uhjA:
undetectable
4qwub-3uhjA:
undetectable		 4qwuV-3uhjA:
21.54
4qwub-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.27A 4qwuH-3uhjA:
undetectable
4qwuN-3uhjA:
undetectable		 4qwuH-3uhjA:
21.54
4qwuN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		3 / 3 ARG A  37
TYR A  47
GLU A  40
 None
 0.68A 4zzbE-3uhjA:
undetectable		 4zzbE-3uhjA:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  67
THR A 138
VAL A  57
GLY A 112
ILE A  41
 None
 1.25A 5b8hA-3uhjA:
undetectable
5b8hB-3uhjA:
undetectable		 5b8hA-3uhjA:
30.87
5b8hB-3uhjA:
30.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.33A 5bxnV-3uhjA:
undetectable
5bxnb-3uhjA:
undetectable		 5bxnV-3uhjA:
21.54
5bxnb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.31A 5bxnH-3uhjA:
undetectable
5bxnN-3uhjA:
undetectable		 5bxnH-3uhjA:
21.54
5bxnN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 5cz7H-3uhjA:
undetectable
5cz7N-3uhjA:
undetectable		 5cz7H-3uhjA:
21.54
5cz7N-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 ASP A 143
SER A 147
ASP A 193
GLU A 270
GLU A 200
 ZN  A 388 (-3.6A)
None
ZN  A 388 (-2.2A)
None
None
 1.30A 5iqcD-3uhjA:
1.5		 5iqcD-3uhjA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.27A 5l5zV-3uhjA:
undetectable
5l5zb-3uhjA:
undetectable		 5l5zV-3uhjA:
21.54
5l5zb-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.26A 5l5zH-3uhjA:
undetectable
5l5zN-3uhjA:
undetectable		 5l5zH-3uhjA:
21.54
5l5zN-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.27A 5l66V-3uhjA:
undetectable
5l66b-3uhjA:
undetectable		 5l66V-3uhjA:
21.54
5l66b-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 THR A 363
SER A 203
GLY A 279
ALA A 277
SER A 196
 None
 1.45A 5l66K-3uhjA:
undetectable
5l66L-3uhjA:
undetectable		 5l66K-3uhjA:
18.59
5l66L-3uhjA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 147
THR A 121
GLY A 115
ALA A 144
THR A 142
 None
None
GOL  A 487 ( 3.8A)
None
GOL  A 487 (-3.6A)
 1.28A 5l66H-3uhjA:
undetectable
5l66N-3uhjA:
undetectable		 5l66H-3uhjA:
21.54
5l66N-3uhjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 THR A 363
SER A 203
GLY A 279
ALA A 277
SER A 196
 None
 1.46A 5l66Y-3uhjA:
undetectable
5l66Z-3uhjA:
undetectable		 5l66Y-3uhjA:
18.59
5l66Z-3uhjA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 ALA A 219
THR A 220
GLU A 221
GLY A 268
THR A 197
 None
 1.21A 5lf3H-3uhjA:
undetectable
5lf3I-3uhjA:
undetectable		 5lf3H-3uhjA:
21.20
5lf3I-3uhjA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 ALA A 219
THR A 220
GLU A 221
GLY A 268
THR A 197
 None
 1.21A 5lf3V-3uhjA:
undetectable
5lf3W-3uhjA:
undetectable		 5lf3V-3uhjA:
21.20
5lf3W-3uhjA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 171
TYR A  47
ARG A  99
ALA A 102
ALA A 131
 None
 1.19A 5n5dA-3uhjA:
3.4		 5n5dA-3uhjA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 SER A 203
ALA A 277
ILE A 376
ALA A 375
 None
 0.79A 5te8B-3uhjA:
undetectable		 5te8B-3uhjA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 287
ILE A 346
ALA A 350
ILE A 360
ALA A 276
 None
 1.04A 5vc0A-3uhjA:
undetectable		 5vc0A-3uhjA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 ALA A 300
VAL A 254
ILE A 258
ASN A 261
THR A 262
 None
 1.31A 5y80A-3uhjA:
undetectable		 5y80A-3uhjA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 TYR A  47
ILE A  35
GLU A  40
ARG A  37
 None
 0.96A 5z3jA-3uhjA:
undetectable		 5z3jA-3uhjA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 116
VAL A 172
GLY A 266
ILE A 149
ILE A 135
 GOL  A 487 (-3.9A)
None
None
None
None
 0.82A 6dj1A-3uhjA:
undetectable		 6dj1A-3uhjA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 6 ALA A 182
SER A 141
GLY A 115
THR A 118
ILE A  59
 None
GOL  A 487 (-2.6A)
GOL  A 487 ( 3.8A)
None
None
 1.44A 6f8cA-3uhjA:
undetectable		 6f8cA-3uhjA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3uhj PROBABLE GLYCEROL
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 GLN A 231
LEU A 307
PHE A 199
GLU A 200
LEU A 195
 None
 1.45A 6ftpA-3uhjA:
undetectable
6ftpB-3uhjA:
undetectable		 6ftpA-3uhjA:
11.66
6ftpB-3uhjA:
7.87