SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3uho'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		6 / 12 ILE A  67
ALA A  95
GLY A  96
HIS A 202
ALA A 206
ILE A 207
 None
None
None
None
EDO  A 264 (-3.3A)
None
 1.23A 1bx4A-3uhoA:
2.8		 1bx4A-3uhoA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 SER A  14
VAL A  15
GLY A  12
GLY A 204
LEU A  78
 None
None
None
None
CL  A 263 (-4.2A)
 1.05A 1fduA-3uhoA:
3.1		 1fduA-3uhoA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		4 / 8 VAL A  37
LEU A  13
TYR A  30
HIS A 182
 DGL  A 260 ( 4.8A)
None
None
DGL  A 260 (-4.3A)
 1.04A 3af0A-3uhoA:
undetectable		 3af0A-3uhoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		4 / 6 ILE A 177
THR A 142
PHE A 167
PHE A 194
 None
 1.20A 3elzB-3uhoA:
undetectable		 3elzB-3uhoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 9 ILE A  68
LEU A  66
ILE A  63
ILE A   3
ILE A  29
 None
 0.98A 3zosA-3uhoA:
undetectable		 3zosA-3uhoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 ILE A  93
ASN A  71
TYR A 125
SER A 203
LEU A  19
 None
DGL  A 260 (-4.1A)
None
None
None
 1.11A 4a84A-3uhoA:
undetectable		 4a84A-3uhoA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 THR A 181
PHE A  25
VAL A   5
ALA A  22
VAL A 208
 DGL  A 260 (-3.0A)
None
None
None
None
 1.15A 4df3A-3uhoA:
undetectable		 4df3A-3uhoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 THR A 181
PHE A  25
VAL A   5
ALA A  22
VAL A 208
 DGL  A 260 (-3.0A)
None
None
None
None
 1.12A 4df3B-3uhoA:
2.5		 4df3B-3uhoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 11 ILE A 207
LEU A  66
ASP A   7
GLY A  12
ALA A  73
 None
None
DGL  A 260 (-3.3A)
None
None
 1.11A 4fogD-3uhoA:
undetectable		 4fogD-3uhoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 9 LEU A  13
GLY A  12
GLU A 150
ILE A 243
THR A 240
 None
 1.44A 4x3mA-3uhoA:
undetectable		 4x3mA-3uhoA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 ALA A 241
LEU A  16
LEU A  13
HIS A 227
LEU A 247
 None
 1.20A 4zn7A-3uhoA:
undetectable		 4zn7A-3uhoA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3uho GLUTAMATE RACEMASE
(Campylobacter
jejuni) 		5 / 12 PHE A 167
ILE A 114
LEU A 190
ALA A 162
LEU A 159
 None
 1.19A 5zwrA-3uhoA:
undetectable		 5zwrA-3uhoA:
21.13